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Brazilian red propolis: unreported substances, antioxidant and antimicrobial activities.
J Sci Food Agric 2011; 91(13):2363-70JS

Abstract

BACKGROUND

Chloroform, ethyl acetate and methanol extracts of a sample of red propolis from the state of Alagoas (northeast Brazil) were analyzed by gas chromatography-mass spectrometry and high-performance liquid chromatography-diode array detection-electrospray ionization-mass spectrometry. Antimicrobial and antioxidant activities were also obtained.

RESULTS

The propolis sample contained low content of narigenin-8-C-hexoside, this being the first report of a C-glycoside in propolis. The main constituent found was characterized as 3,4,2',3'-tetrahydroxychalcone. Other important constituents were the chalcone isoliquiritigenin, the isoflavans (3S)-vestitol, (3S)-7-O-methylvestitol, the pterocarpan medicarpin, the phenylpropenes trans-anethol, methyl eugenol, elimicin, methoxyeugenol and cis-asarone, and the triterpenic alcohols lupeol and α- and β- amyrins. The methanol extract exhibited high antioxidant activities by 2,2-diphenyl-1-picrylhydrazyl and β-carotene/linoleic acid assay methods, and antimicrobial activity toward Gram-positive and Gram-negative bacteria.

CONCLUSION

Structures are suggested for new substances never before seen in any kind of propolis. This is the first report of 3,4,2',3'-tetrahydroxychalcone and a flavone C-glycoside in a propolis sample.

Authors+Show Affiliations

Institute of Biosciences, Botany Department, University of São Paulo, São Paulo, SP, Brazil. adnerighi@gmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21590778

Citation

Righi, Adne A., et al. "Brazilian Red Propolis: Unreported Substances, Antioxidant and Antimicrobial Activities." Journal of the Science of Food and Agriculture, vol. 91, no. 13, 2011, pp. 2363-70.
Righi AA, Alves TR, Negri G, et al. Brazilian red propolis: unreported substances, antioxidant and antimicrobial activities. J Sci Food Agric. 2011;91(13):2363-70.
Righi, A. A., Alves, T. R., Negri, G., Marques, L. M., Breyer, H., & Salatino, A. (2011). Brazilian red propolis: unreported substances, antioxidant and antimicrobial activities. Journal of the Science of Food and Agriculture, 91(13), pp. 2363-70. doi:10.1002/jsfa.4468.
Righi AA, et al. Brazilian Red Propolis: Unreported Substances, Antioxidant and Antimicrobial Activities. J Sci Food Agric. 2011;91(13):2363-70. PubMed PMID: 21590778.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Brazilian red propolis: unreported substances, antioxidant and antimicrobial activities. AU - Righi,Adne A, AU - Alves,Thiago R, AU - Negri,Giuseppina, AU - Marques,Lucas M, AU - Breyer,Henrique, AU - Salatino,Antonio, Y1 - 2011/05/17/ PY - 2010/12/21/received PY - 2011/03/18/revised PY - 2011/04/09/accepted PY - 2011/5/19/entrez PY - 2011/5/19/pubmed PY - 2012/1/25/medline SP - 2363 EP - 70 JF - Journal of the science of food and agriculture JO - J. Sci. Food Agric. VL - 91 IS - 13 N2 - BACKGROUND: Chloroform, ethyl acetate and methanol extracts of a sample of red propolis from the state of Alagoas (northeast Brazil) were analyzed by gas chromatography-mass spectrometry and high-performance liquid chromatography-diode array detection-electrospray ionization-mass spectrometry. Antimicrobial and antioxidant activities were also obtained. RESULTS: The propolis sample contained low content of narigenin-8-C-hexoside, this being the first report of a C-glycoside in propolis. The main constituent found was characterized as 3,4,2',3'-tetrahydroxychalcone. Other important constituents were the chalcone isoliquiritigenin, the isoflavans (3S)-vestitol, (3S)-7-O-methylvestitol, the pterocarpan medicarpin, the phenylpropenes trans-anethol, methyl eugenol, elimicin, methoxyeugenol and cis-asarone, and the triterpenic alcohols lupeol and α- and β- amyrins. The methanol extract exhibited high antioxidant activities by 2,2-diphenyl-1-picrylhydrazyl and β-carotene/linoleic acid assay methods, and antimicrobial activity toward Gram-positive and Gram-negative bacteria. CONCLUSION: Structures are suggested for new substances never before seen in any kind of propolis. This is the first report of 3,4,2',3'-tetrahydroxychalcone and a flavone C-glycoside in a propolis sample. SN - 1097-0010 UR - https://www.unboundmedicine.com/medline/citation/21590778/Brazilian_red_propolis:_unreported_substances_antioxidant_and_antimicrobial_activities_ L2 - https://doi.org/10.1002/jsfa.4468 DB - PRIME DP - Unbound Medicine ER -