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Importance of surface coatings and soluble silver in silver nanoparticles toxicity to Daphnia magna.
Nanotoxicology. 2012 Jun; 6(4):361-70.N

Abstract

Silver nanoparticles (AgNPs) are now widely used in antibacterial and personal care products. However, the underlying physicochemical mechanisms leading to the toxicity of AgNPs are still under debate. The present study revealed the different effects of three surface coatings (including lactate, polyvinylpyrrolidone, and sodium dodecylbenzene sulfonate, as AgNPs-L, AgNPs-P and AgNPs-S, respectively) on the acute toxicity of AgNPs to a model freshwater cladoceran Daphnia magna. Significant difference in mortality was observed among these three surface coatings of AgNPs, with the 48-h 50% lethal concentrations (48-h LC50s) of AgNPs-L, AgNPs-P and AgNPs-S being 28.7, 2.0 and 1.1 μg/L, respectively. In contrast, when the daphnids were exposed to soluble Ag released from AgNPs-L and AgNPs-P, the difference in the 48-h LC50s between the two surface coatings (1.1 μg/L and 0.57 μg/L, respectively) decreased significantly. These 48-h LC50s were comparable to that of AgNO₃ (0.88 μg/L), indicating that soluble Ag was the primarily cause of the observed toxicity of AgNPs. Indeed, the surface coatings influenced the dissolution of AgNPs into soluble Ag, resulting in the different toxicities of AgNP to the daphnids. Additionally, the 48-h bioaccumulation of AgNPs in daphnids was also dependent on the characteristics of the nanoparticles, such as particle size and surface coating. Our results point to the need to consider the effects of surface coating on the toxicity of AgNPs in environmental risk assessments.

Authors+Show Affiliations

Division of Life Science, The Hong Kong University of Science and Technology-HKUST, Clear Water Bay, Kowloon, Hong Kong.No affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21591875

Citation

Zhao, Chun-Mei, and Wen-Xiong Wang. "Importance of Surface Coatings and Soluble Silver in Silver Nanoparticles Toxicity to Daphnia Magna." Nanotoxicology, vol. 6, no. 4, 2012, pp. 361-70.
Zhao CM, Wang WX. Importance of surface coatings and soluble silver in silver nanoparticles toxicity to Daphnia magna. Nanotoxicology. 2012;6(4):361-70.
Zhao, C. M., & Wang, W. X. (2012). Importance of surface coatings and soluble silver in silver nanoparticles toxicity to Daphnia magna. Nanotoxicology, 6(4), 361-70. https://doi.org/10.3109/17435390.2011.579632
Zhao CM, Wang WX. Importance of Surface Coatings and Soluble Silver in Silver Nanoparticles Toxicity to Daphnia Magna. Nanotoxicology. 2012;6(4):361-70. PubMed PMID: 21591875.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Importance of surface coatings and soluble silver in silver nanoparticles toxicity to Daphnia magna. AU - Zhao,Chun-Mei, AU - Wang,Wen-Xiong, Y1 - 2011/05/18/ PY - 2011/5/20/entrez PY - 2011/5/20/pubmed PY - 2012/9/25/medline SP - 361 EP - 70 JF - Nanotoxicology JO - Nanotoxicology VL - 6 IS - 4 N2 - Silver nanoparticles (AgNPs) are now widely used in antibacterial and personal care products. However, the underlying physicochemical mechanisms leading to the toxicity of AgNPs are still under debate. The present study revealed the different effects of three surface coatings (including lactate, polyvinylpyrrolidone, and sodium dodecylbenzene sulfonate, as AgNPs-L, AgNPs-P and AgNPs-S, respectively) on the acute toxicity of AgNPs to a model freshwater cladoceran Daphnia magna. Significant difference in mortality was observed among these three surface coatings of AgNPs, with the 48-h 50% lethal concentrations (48-h LC50s) of AgNPs-L, AgNPs-P and AgNPs-S being 28.7, 2.0 and 1.1 μg/L, respectively. In contrast, when the daphnids were exposed to soluble Ag released from AgNPs-L and AgNPs-P, the difference in the 48-h LC50s between the two surface coatings (1.1 μg/L and 0.57 μg/L, respectively) decreased significantly. These 48-h LC50s were comparable to that of AgNO₃ (0.88 μg/L), indicating that soluble Ag was the primarily cause of the observed toxicity of AgNPs. Indeed, the surface coatings influenced the dissolution of AgNPs into soluble Ag, resulting in the different toxicities of AgNP to the daphnids. Additionally, the 48-h bioaccumulation of AgNPs in daphnids was also dependent on the characteristics of the nanoparticles, such as particle size and surface coating. Our results point to the need to consider the effects of surface coating on the toxicity of AgNPs in environmental risk assessments. SN - 1743-5404 UR - https://www.unboundmedicine.com/medline/citation/21591875/Importance_of_surface_coatings_and_soluble_silver_in_silver_nanoparticles_toxicity_to_Daphnia_magna_ L2 - https://www.tandfonline.com/doi/full/10.3109/17435390.2011.579632 DB - PRIME DP - Unbound Medicine ER -