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Evaluation of delirium in elderly: a hospital-based study.
Geriatr Gerontol Int. 2011 Oct; 11(4):467-73.GG

Abstract

AIM

The study aimed to study the prevalence, etiologies, clinical profile and outcome of delirium in hospitalized elderly in medicine wards.

METHODS

Four hundred elderly patients of more than 60years of age admitted with delirium in the emergency and medicine wards of Sir Sunderlal Hospital Varanasi, India, were evaluated and managed. The Hindi version of the Mini-Mental Status Examinations, a vernacular (Hindi) version of the Mini-Mental State Examination, was used for evaluation of cognitive function status of patients and Confusion Assessment Method (CAM), a screening instrument based on the third edition of the Diagnostic and Statistical Manual of Mental Disorders was used for diagnosis of delirium.

RESULTS

A total of 400 hospitalized elderly delirious patients were included in the study aged 61-105years. The mean age of the subjects was 70.87±9.26years and 70.81±8.4years amongst males and females, respectively. The mortality rate was 14.75%. Out of nine CAM features, all the cases had all three essential features, 78.75% had four features, 58.5% had five features, 44.5% had six features and 9.25% had all nine features. There was a high prevalence of hypoactive delirium (65%) as compared to hyperactive (25%) or mixed (10%). Most common etiologies were sepsis followed by metabolic abnormalities. 70% had 2 or more etiologies.

CONCLUSION

Sepsis and metabolic abnormalities were the most common etiologies of delirium in this study. The maximum patients had more than one etiology and this emphasizes the multifactorial nature of delirium and need for thorough evaluation to unravel them. Most of the causes were treatable and have favorable outcome (83% recovered).

Authors+Show Affiliations

Departments of Department of General Medicine, Institute of Medical Sciences (IMS), Banaras Hindu University (BHU), Varanasi, India. vishdoc24@gmail.comNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21592270

Citation

Khurana, Vishal, et al. "Evaluation of Delirium in Elderly: a Hospital-based Study." Geriatrics & Gerontology International, vol. 11, no. 4, 2011, pp. 467-73.
Khurana V, Gambhir IS, Kishore D. Evaluation of delirium in elderly: a hospital-based study. Geriatr Gerontol Int. 2011;11(4):467-73.
Khurana, V., Gambhir, I. S., & Kishore, D. (2011). Evaluation of delirium in elderly: a hospital-based study. Geriatrics & Gerontology International, 11(4), 467-73. https://doi.org/10.1111/j.1447-0594.2011.00710.x
Khurana V, Gambhir IS, Kishore D. Evaluation of Delirium in Elderly: a Hospital-based Study. Geriatr Gerontol Int. 2011;11(4):467-73. PubMed PMID: 21592270.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of delirium in elderly: a hospital-based study. AU - Khurana,Vishal, AU - Gambhir,Indrajeet Singh, AU - Kishore,Dhiraj, Y1 - 2011/05/18/ PY - 2011/5/20/entrez PY - 2011/5/20/pubmed PY - 2012/1/27/medline SP - 467 EP - 73 JF - Geriatrics & gerontology international JO - Geriatr Gerontol Int VL - 11 IS - 4 N2 - AIM: The study aimed to study the prevalence, etiologies, clinical profile and outcome of delirium in hospitalized elderly in medicine wards. METHODS: Four hundred elderly patients of more than 60years of age admitted with delirium in the emergency and medicine wards of Sir Sunderlal Hospital Varanasi, India, were evaluated and managed. The Hindi version of the Mini-Mental Status Examinations, a vernacular (Hindi) version of the Mini-Mental State Examination, was used for evaluation of cognitive function status of patients and Confusion Assessment Method (CAM), a screening instrument based on the third edition of the Diagnostic and Statistical Manual of Mental Disorders was used for diagnosis of delirium. RESULTS: A total of 400 hospitalized elderly delirious patients were included in the study aged 61-105years. The mean age of the subjects was 70.87±9.26years and 70.81±8.4years amongst males and females, respectively. The mortality rate was 14.75%. Out of nine CAM features, all the cases had all three essential features, 78.75% had four features, 58.5% had five features, 44.5% had six features and 9.25% had all nine features. There was a high prevalence of hypoactive delirium (65%) as compared to hyperactive (25%) or mixed (10%). Most common etiologies were sepsis followed by metabolic abnormalities. 70% had 2 or more etiologies. CONCLUSION: Sepsis and metabolic abnormalities were the most common etiologies of delirium in this study. The maximum patients had more than one etiology and this emphasizes the multifactorial nature of delirium and need for thorough evaluation to unravel them. Most of the causes were treatable and have favorable outcome (83% recovered). SN - 1447-0594 UR - https://www.unboundmedicine.com/medline/citation/21592270/Evaluation_of_delirium_in_elderly:_a_hospital_based_study_ L2 - https://doi.org/10.1111/j.1447-0594.2011.00710.x DB - PRIME DP - Unbound Medicine ER -