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Postoperative surveillance and detection of postprandial hypoglycemia after fundoplasty in children.
J Pediatr. 2011 Oct; 159(4):597-601.e1.JPed

Abstract

OBJECTIVE

To evaluate the prevalence of postprandial hypoglycemia (PPH) after fundoplasty after the initiation of a universal postoperative glucose surveillance plan in the neonatal intensive care unit (NICU).

STUDY DESIGN

This was a retrospective chart review of children (newborn to 18 years) who underwent fundoplasty at The Children's Hospital of Philadelphia during the 2-year-period after the launch of a surveillance protocol in the NICU and other units. The rate of screening, frequency of PPH (postprandial blood glucose <60 mg/dL [3.3 mmol/L] on 2 occasions), frequency of postprandial hyperglycemia preceding PPH, timing of PPH presentation, and related symptoms were evaluated.

RESULTS

A total of 285 children were included (n = 64 in the NICU; n = 221 in other units). Of the children screened in all units, 24.0% showed evidence of PPH, compared with 1.3% of unscreened children. Hyperglycemia preceded PPH in 67.7% (21/31) of all screened children. Within the NICU, most children had PPH within 1 week, but only 53.3% exhibited symptoms of dumping syndrome.

CONCLUSIONS

This study supports the use of universal postoperative blood glucose surveillance in identifying PPH in children after fundoplasty. Earlier identification of PPH would lead to earlier treatment and minimize the effects of unidentified hypoglycemic events.

Authors+Show Affiliations

Division of Endocrinology and Diabetes, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21592499

Citation

Calabria, Andrew C., et al. "Postoperative Surveillance and Detection of Postprandial Hypoglycemia After Fundoplasty in Children." The Journal of Pediatrics, vol. 159, no. 4, 2011, pp. 597-601.e1.
Calabria AC, Gallagher PR, Simmons R, et al. Postoperative surveillance and detection of postprandial hypoglycemia after fundoplasty in children. J Pediatr. 2011;159(4):597-601.e1.
Calabria, A. C., Gallagher, P. R., Simmons, R., Blinman, T., & De León, D. D. (2011). Postoperative surveillance and detection of postprandial hypoglycemia after fundoplasty in children. The Journal of Pediatrics, 159(4), 597-e1. https://doi.org/10.1016/j.jpeds.2011.03.049
Calabria AC, et al. Postoperative Surveillance and Detection of Postprandial Hypoglycemia After Fundoplasty in Children. J Pediatr. 2011;159(4):597-601.e1. PubMed PMID: 21592499.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Postoperative surveillance and detection of postprandial hypoglycemia after fundoplasty in children. AU - Calabria,Andrew C, AU - Gallagher,Paul R, AU - Simmons,Rebecca, AU - Blinman,Thane, AU - De León,Diva D, Y1 - 2011/05/17/ PY - 2010/12/14/received PY - 2011/02/11/revised PY - 2011/03/22/accepted PY - 2011/5/20/entrez PY - 2011/5/20/pubmed PY - 2011/12/13/medline SP - 597 EP - 601.e1 JF - The Journal of pediatrics JO - J Pediatr VL - 159 IS - 4 N2 - OBJECTIVE: To evaluate the prevalence of postprandial hypoglycemia (PPH) after fundoplasty after the initiation of a universal postoperative glucose surveillance plan in the neonatal intensive care unit (NICU). STUDY DESIGN: This was a retrospective chart review of children (newborn to 18 years) who underwent fundoplasty at The Children's Hospital of Philadelphia during the 2-year-period after the launch of a surveillance protocol in the NICU and other units. The rate of screening, frequency of PPH (postprandial blood glucose <60 mg/dL [3.3 mmol/L] on 2 occasions), frequency of postprandial hyperglycemia preceding PPH, timing of PPH presentation, and related symptoms were evaluated. RESULTS: A total of 285 children were included (n = 64 in the NICU; n = 221 in other units). Of the children screened in all units, 24.0% showed evidence of PPH, compared with 1.3% of unscreened children. Hyperglycemia preceded PPH in 67.7% (21/31) of all screened children. Within the NICU, most children had PPH within 1 week, but only 53.3% exhibited symptoms of dumping syndrome. CONCLUSIONS: This study supports the use of universal postoperative blood glucose surveillance in identifying PPH in children after fundoplasty. Earlier identification of PPH would lead to earlier treatment and minimize the effects of unidentified hypoglycemic events. SN - 1097-6833 UR - https://www.unboundmedicine.com/medline/citation/21592499/Postoperative_surveillance_and_detection_of_postprandial_hypoglycemia_after_fundoplasty_in_children_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0022-3476(11)00341-6 DB - PRIME DP - Unbound Medicine ER -