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Diagnosis and clinical features of epidermolysis bullosa acquisita.
Dermatol Clin. 2011 Jul; 29(3):485-91, x.DC

Abstract

Epidermolysis bullosa acquisita (EBA) is a rare autoimmune subepidermal blistering disease characterized by immune deposits on anchoring fibrils of cutaneous and mucosal basement membrane zones. It is due to circulating antibodies directed to type VII collagen. Clinical manifestations include a classical form with skin fragility, blisters and scars on trauma-prone surfaces, an inflammatory form, and a cicatricial pemphigoid-like form. Specialized tests available in only certain laboratories are necessary to confirm a diagnosis of EBA, such as immunoelectron microscopy, immunoblotting, or ELISA using recombinant proteins. A frequent association between EBA and Crohn disease has been observed.

Authors+Show Affiliations

Department of Dermatology & Reference Center on Autoimmune Bullous Diseases, University Paris 13, Avicenne Hospital, AP-HP, 125 rue de Stalingrad, 93000 Bobigny, France. frederic.caux@avc.aphp.fr

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

21605816

Citation

Caux, Frédéric. "Diagnosis and Clinical Features of Epidermolysis Bullosa Acquisita." Dermatologic Clinics, vol. 29, no. 3, 2011, pp. 485-91, x.
Caux F. Diagnosis and clinical features of epidermolysis bullosa acquisita. Dermatol Clin. 2011;29(3):485-91, x.
Caux, F. (2011). Diagnosis and clinical features of epidermolysis bullosa acquisita. Dermatologic Clinics, 29(3), 485-91, x. https://doi.org/10.1016/j.det.2011.03.017
Caux F. Diagnosis and Clinical Features of Epidermolysis Bullosa Acquisita. Dermatol Clin. 2011;29(3):485-91, x. PubMed PMID: 21605816.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diagnosis and clinical features of epidermolysis bullosa acquisita. A1 - Caux,Frédéric, PY - 2011/5/25/entrez PY - 2011/5/25/pubmed PY - 2011/9/23/medline SP - 485-91, x JF - Dermatologic clinics JO - Dermatol Clin VL - 29 IS - 3 N2 - Epidermolysis bullosa acquisita (EBA) is a rare autoimmune subepidermal blistering disease characterized by immune deposits on anchoring fibrils of cutaneous and mucosal basement membrane zones. It is due to circulating antibodies directed to type VII collagen. Clinical manifestations include a classical form with skin fragility, blisters and scars on trauma-prone surfaces, an inflammatory form, and a cicatricial pemphigoid-like form. Specialized tests available in only certain laboratories are necessary to confirm a diagnosis of EBA, such as immunoelectron microscopy, immunoblotting, or ELISA using recombinant proteins. A frequent association between EBA and Crohn disease has been observed. SN - 1558-0520 UR - https://www.unboundmedicine.com/medline/citation/21605816/Diagnosis_and_clinical_features_of_epidermolysis_bullosa_acquisita_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0733-8635(11)00073-8 DB - PRIME DP - Unbound Medicine ER -