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Ruthenium-catalyzed oxidative synthesis of 2-pyridones through C-H/N-H bond functionalizations.
Org Lett. 2011 Jun 17; 13(12):3278-81.OL

Abstract

An inexpensive ruthenium catalyst enabled oxidative annulations of alkynes by acrylamides with ample scope, which allowed for the preparation of 2-pyridones employing various electron-rich and electron-deficient acrylamides as well as (di)aryl- and (di)alkyl-substituted alkynes.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Ackermann L
Institut für Organische und Biomolekulare Chemie, Georg-August-Universität, Tammannstrasse 2, 37077 Göttingen, Germany. Lutz.Ackermann@chemie.uni-goettingen.de
Lygin AV
No affiliation info available
Hofmann N
No affiliation info available

MeSH

AlkynesCatalysisChemistry, OrganicMolecular StructureOxidation-ReductionPyridonesRutheniumStereoisomerism

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21612195

Citation

Ackermann, Lutz, et al. "Ruthenium-catalyzed Oxidative Synthesis of 2-pyridones Through C-H/N-H Bond Functionalizations." Organic Letters, vol. 13, no. 12, 2011, pp. 3278-81.
Ackermann L, Lygin AV, Hofmann N. Ruthenium-catalyzed oxidative synthesis of 2-pyridones through C-H/N-H bond functionalizations. Org Lett. 2011;13(12):3278-81.
Ackermann, L., Lygin, A. V., & Hofmann, N. (2011). Ruthenium-catalyzed oxidative synthesis of 2-pyridones through C-H/N-H bond functionalizations. Organic Letters, 13(12), 3278-81. https://doi.org/10.1021/ol201244s
Ackermann L, Lygin AV, Hofmann N. Ruthenium-catalyzed Oxidative Synthesis of 2-pyridones Through C-H/N-H Bond Functionalizations. Org Lett. 2011 Jun 17;13(12):3278-81. PubMed PMID: 21612195.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Ruthenium-catalyzed oxidative synthesis of 2-pyridones through C-H/N-H bond functionalizations. AU - Ackermann,Lutz, AU - Lygin,Alexander V, AU - Hofmann,Nora, Y1 - 2011/05/25/ PY - 2011/5/27/entrez PY - 2011/5/27/pubmed PY - 2011/9/21/medline SP - 3278 EP - 81 JF - Organic letters JO - Org Lett VL - 13 IS - 12 N2 - An inexpensive ruthenium catalyst enabled oxidative annulations of alkynes by acrylamides with ample scope, which allowed for the preparation of 2-pyridones employing various electron-rich and electron-deficient acrylamides as well as (di)aryl- and (di)alkyl-substituted alkynes. SN - 1523-7052 UR - https://www.unboundmedicine.com/medline/citation/21612195/Ruthenium_catalyzed_oxidative_synthesis_of_2_pyridones_through_C_H/N_H_bond_functionalizations_ L2 - https://doi.org/10.1021/ol201244s DB - PRIME DP - Unbound Medicine ER -