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Clinical utility of probiotics in inflammatory bowel disease.
Altern Ther Health Med 2011 Jan-Feb; 17(1):72-9AT

Abstract

Many patients with inflammatory bowel disease (IBD) use probiotics to manage this intestinal condition. Despite widespread use of these natural therapies by patients, health care providers may be unfamiliar with probiotics as a treatment modality. This review describes the rationale for use of probiotics in IBD, the history behind current research directions, and recent controlled clinical studies in which efficacy of probiotics has been explored in patients with IBD. Emphasis is placed upon critical analysis of study designs for investigations that used lactic acid-producing bacteria or Saccharomyces boulardii in management of Crohn's disease or ulcerative colitis. While there is suggestion of benefit when patients with ulcerative colitis use bacterial therapies and when patients with Crohn's disease use S boulardii, small sample sizes and methodological flaws in study designs necessitate that additional investigations be conducted before probiotics can be routinely recommended in clinical practice.

Authors+Show Affiliations

York Hospital, Pennsylvania, USA.No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

21614946

Citation

Cain, Alisha M., and Kelly Dowhower Karpa. "Clinical Utility of Probiotics in Inflammatory Bowel Disease." Alternative Therapies in Health and Medicine, vol. 17, no. 1, 2011, pp. 72-9.
Cain AM, Karpa KD. Clinical utility of probiotics in inflammatory bowel disease. Altern Ther Health Med. 2011;17(1):72-9.
Cain, A. M., & Karpa, K. D. (2011). Clinical utility of probiotics in inflammatory bowel disease. Alternative Therapies in Health and Medicine, 17(1), pp. 72-9.
Cain AM, Karpa KD. Clinical Utility of Probiotics in Inflammatory Bowel Disease. Altern Ther Health Med. 2011;17(1):72-9. PubMed PMID: 21614946.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical utility of probiotics in inflammatory bowel disease. AU - Cain,Alisha M, AU - Karpa,Kelly Dowhower, PY - 2011/5/28/entrez PY - 2011/5/28/pubmed PY - 2011/6/22/medline SP - 72 EP - 9 JF - Alternative therapies in health and medicine JO - Altern Ther Health Med VL - 17 IS - 1 N2 - Many patients with inflammatory bowel disease (IBD) use probiotics to manage this intestinal condition. Despite widespread use of these natural therapies by patients, health care providers may be unfamiliar with probiotics as a treatment modality. This review describes the rationale for use of probiotics in IBD, the history behind current research directions, and recent controlled clinical studies in which efficacy of probiotics has been explored in patients with IBD. Emphasis is placed upon critical analysis of study designs for investigations that used lactic acid-producing bacteria or Saccharomyces boulardii in management of Crohn's disease or ulcerative colitis. While there is suggestion of benefit when patients with ulcerative colitis use bacterial therapies and when patients with Crohn's disease use S boulardii, small sample sizes and methodological flaws in study designs necessitate that additional investigations be conducted before probiotics can be routinely recommended in clinical practice. SN - 1078-6791 UR - https://www.unboundmedicine.com/medline/citation/21614946/Clinical_utility_of_probiotics_in_inflammatory_bowel_disease_ DB - PRIME DP - Unbound Medicine ER -