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Food allergy in adults and children.

Abstract

Food allergy is defined as an adverse health effect arising from a specific immune response that occurs reproducibly on exposure to a given food and is distinct from food intolerance. Clinical manifestations of food allergy are varied and involve many systems including respiratory, cutaneous, and gastrointestinal. The double-blinded placebo-controlled oral food challenge remains the gold standard for the diagnosis of IgE-mediated food allergy. Areas of ongoing research include improved understanding of determinants for the development of tolerance versus sensitization for foods, the role of diagnostic testing for specific epitopes for food allergens, and the use of oral immunotherapy for IgE-mediated food allergy.

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  • Authors+Show Affiliations

    ,

    Department of Otolaryngology-Head and Neck Surgery, Boston University Medical Center, Boston, MA 02118, USA. elizabeth.mahoney@bmc.org

    ,

    Source

    Otolaryngologic clinics of North America 44:3 2011 Jun pg 815-33, xii

    MeSH

    Adult
    Allergens
    Child
    Dermatitis, Atopic
    Diagnosis, Differential
    Food Hypersensitivity
    Humans
    Hypersensitivity, Immediate
    Immune Tolerance

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    21621063

    Citation

    Mahoney, Elizabeth J., et al. "Food Allergy in Adults and Children." Otolaryngologic Clinics of North America, vol. 44, no. 3, 2011, pp. 815-33, xii.
    Mahoney EJ, Veling MC, Mims JW. Food allergy in adults and children. Otolaryngol Clin North Am. 2011;44(3):815-33, xii.
    Mahoney, E. J., Veling, M. C., & Mims, J. W. (2011). Food allergy in adults and children. Otolaryngologic Clinics of North America, 44(3), pp. 815-33, xii. doi:10.1016/j.otc.2011.03.014.
    Mahoney EJ, Veling MC, Mims JW. Food Allergy in Adults and Children. Otolaryngol Clin North Am. 2011;44(3):815-33, xii. PubMed PMID: 21621063.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Food allergy in adults and children. AU - Mahoney,Elizabeth J, AU - Veling,Maria C, AU - Mims,James W, Y1 - 2011/05/04/ PY - 2011/5/31/entrez PY - 2011/5/31/pubmed PY - 2011/9/29/medline SP - 815-33, xii JF - Otolaryngologic clinics of North America JO - Otolaryngol. Clin. North Am. VL - 44 IS - 3 N2 - Food allergy is defined as an adverse health effect arising from a specific immune response that occurs reproducibly on exposure to a given food and is distinct from food intolerance. Clinical manifestations of food allergy are varied and involve many systems including respiratory, cutaneous, and gastrointestinal. The double-blinded placebo-controlled oral food challenge remains the gold standard for the diagnosis of IgE-mediated food allergy. Areas of ongoing research include improved understanding of determinants for the development of tolerance versus sensitization for foods, the role of diagnostic testing for specific epitopes for food allergens, and the use of oral immunotherapy for IgE-mediated food allergy. SN - 1557-8259 UR - https://www.unboundmedicine.com/medline/citation/21621063/Food_allergy_in_adults_and_children_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0030-6665(11)00058-2 DB - PRIME DP - Unbound Medicine ER -