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Prevalence and causes of visual impairment and blindness in an urban Indian population: the Singapore Indian Eye Study.
Ophthalmology. 2011 Sep; 118(9):1798-804.O

Abstract

PURPOSE

To describe the prevalence and causes of visual impairment and blindness in an urban Indian population.

DESIGN

Population-based study.

PARTICIPANTS

Ethnic Indians aged more than 40 years living in Singapore.

METHODS

Participants underwent standardized ophthalmic assessments for visual impairment and blindness, defined using best-corrected visual acuity (BCVA) and presenting visual acuity (PVA), according to US and modified World Health Organization (WHO) definitions.

MAIN OUTCOME MEASURES

Unilateral visual impairment or blindness was defined on the basis of the worse eye, and bilateral visual impairment or blindness was defined on the basis of the better eye. Primary causes of visual impairment were determined.

RESULTS

A total of 3400 eligible individuals (75.6% response rate) participated. On the basis of US definitions, the age-standardized prevalence was 0.4% for bilateral blindness (≤20/200, better eye) and 3.4% for bilateral visual impairment (<20/40 to >20/200, better eye). Another 0.3% of bilateral blindness and 13.4% of bilateral visual impairment were correctable with refraction. Cataract was the principal cause of best-corrected bilateral blindness (60.0%) and bilateral visual impairment (65.7%). Other major causes of blindness and visual impairment included diabetic retinopathy, age-related macular degeneration, glaucoma, corneal opacity, and myopic maculopathy.

CONCLUSIONS

The prevalence of bilateral blindness and visual impairment in Indians living in Singapore is lower than estimates from populations living in India, but similar to estimates obtained from Singapore Malay and Chinese populations. Cataract is the leading cause of blindness and visual impairment. One in 20 cases of bilateral blindness and 1 in 10 cases of bilateral visual impairment are attributable to diabetic retinopathy. These data may have relevance to many ethnic Indian persons living outside India.

Authors+Show Affiliations

Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21621261

Citation

Zheng, Yingfeng, et al. "Prevalence and Causes of Visual Impairment and Blindness in an Urban Indian Population: the Singapore Indian Eye Study." Ophthalmology, vol. 118, no. 9, 2011, pp. 1798-804.
Zheng Y, Lavanya R, Wu R, et al. Prevalence and causes of visual impairment and blindness in an urban Indian population: the Singapore Indian Eye Study. Ophthalmology. 2011;118(9):1798-804.
Zheng, Y., Lavanya, R., Wu, R., Wong, W. L., Wang, J. J., Mitchell, P., Cheung, N., Cajucom-Uy, H., Lamoureux, E., Aung, T., Saw, S. M., & Wong, T. Y. (2011). Prevalence and causes of visual impairment and blindness in an urban Indian population: the Singapore Indian Eye Study. Ophthalmology, 118(9), 1798-804. https://doi.org/10.1016/j.ophtha.2011.02.014
Zheng Y, et al. Prevalence and Causes of Visual Impairment and Blindness in an Urban Indian Population: the Singapore Indian Eye Study. Ophthalmology. 2011;118(9):1798-804. PubMed PMID: 21621261.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence and causes of visual impairment and blindness in an urban Indian population: the Singapore Indian Eye Study. AU - Zheng,Yingfeng, AU - Lavanya,Raghavan, AU - Wu,Renyi, AU - Wong,Wan-Ling, AU - Wang,Jie Jin, AU - Mitchell,Paul, AU - Cheung,Ning, AU - Cajucom-Uy,Howard, AU - Lamoureux,Ecosse, AU - Aung,Tin, AU - Saw,Seang-Mei, AU - Wong,Tien Y, Y1 - 2011/05/31/ PY - 2010/11/01/received PY - 2011/02/04/revised PY - 2011/02/04/accepted PY - 2011/5/31/entrez PY - 2011/5/31/pubmed PY - 2011/10/25/medline SP - 1798 EP - 804 JF - Ophthalmology JO - Ophthalmology VL - 118 IS - 9 N2 - PURPOSE: To describe the prevalence and causes of visual impairment and blindness in an urban Indian population. DESIGN: Population-based study. PARTICIPANTS: Ethnic Indians aged more than 40 years living in Singapore. METHODS: Participants underwent standardized ophthalmic assessments for visual impairment and blindness, defined using best-corrected visual acuity (BCVA) and presenting visual acuity (PVA), according to US and modified World Health Organization (WHO) definitions. MAIN OUTCOME MEASURES: Unilateral visual impairment or blindness was defined on the basis of the worse eye, and bilateral visual impairment or blindness was defined on the basis of the better eye. Primary causes of visual impairment were determined. RESULTS: A total of 3400 eligible individuals (75.6% response rate) participated. On the basis of US definitions, the age-standardized prevalence was 0.4% for bilateral blindness (≤20/200, better eye) and 3.4% for bilateral visual impairment (<20/40 to >20/200, better eye). Another 0.3% of bilateral blindness and 13.4% of bilateral visual impairment were correctable with refraction. Cataract was the principal cause of best-corrected bilateral blindness (60.0%) and bilateral visual impairment (65.7%). Other major causes of blindness and visual impairment included diabetic retinopathy, age-related macular degeneration, glaucoma, corneal opacity, and myopic maculopathy. CONCLUSIONS: The prevalence of bilateral blindness and visual impairment in Indians living in Singapore is lower than estimates from populations living in India, but similar to estimates obtained from Singapore Malay and Chinese populations. Cataract is the leading cause of blindness and visual impairment. One in 20 cases of bilateral blindness and 1 in 10 cases of bilateral visual impairment are attributable to diabetic retinopathy. These data may have relevance to many ethnic Indian persons living outside India. SN - 1549-4713 UR - https://www.unboundmedicine.com/medline/citation/21621261/Prevalence_and_causes_of_visual_impairment_and_blindness_in_an_urban_Indian_population:_the_Singapore_Indian_Eye_Study_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0161-6420(11)00173-4 DB - PRIME DP - Unbound Medicine ER -