Tags

Type your tag names separated by a space and hit enter

What, how, and how much should patients with burns be fed?

Abstract

The hypermetabolic response to severe burn injury is characterized by hyperdynamic circulation and profound metabolic, physiologic, catabolic, and immune system derangements. Failure to satisfy overwhelming energy and protein requirements after, and during, severe burn injury results in multiorgan dysfunction, increased susceptibility to infection, and death. Attenuation of the hypermetabolic response by various pharmacologic modalities is emerging as an essential component of the management of patients with severe burn injury. This review focuses on the more recent advances in therapeutic strategies to attenuate the hypermetabolic response and its postburn-associated insulin resistance.

Links

  • PMC Free PDF
  • PMC Free Full Text
  • Publisher Full Text
  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Department of Surgery, Shriners Hospital for Children and University of Texas Medical Branch, 815 Market Street, Galveston, TX 77550, USA.

    , ,

    Source

    MeSH

    Animals
    Blood Glucose
    Burns
    Catecholamines
    Enteral Nutrition
    Humans
    Hypoglycemic Agents
    Insulin Resistance
    Lipolysis
    Liver
    Metformin
    Multiple Organ Failure
    Muscle, Skeletal
    Nutritional Support
    Parenteral Nutrition, Total
    Wound Healing

    Pub Type(s)

    Journal Article
    Research Support, N.I.H., Extramural
    Research Support, Non-U.S. Gov't
    Review

    Language

    eng

    PubMed ID

    21621699

    Citation

    Williams, Felicia N., et al. "What, How, and How Much Should Patients With Burns Be Fed?" The Surgical Clinics of North America, vol. 91, no. 3, 2011, pp. 609-29.
    Williams FN, Branski LK, Jeschke MG, et al. What, how, and how much should patients with burns be fed? Surg Clin North Am. 2011;91(3):609-29.
    Williams, F. N., Branski, L. K., Jeschke, M. G., & Herndon, D. N. (2011). What, how, and how much should patients with burns be fed? The Surgical Clinics of North America, 91(3), pp. 609-29. doi:10.1016/j.suc.2011.03.002.
    Williams FN, et al. What, How, and How Much Should Patients With Burns Be Fed. Surg Clin North Am. 2011;91(3):609-29. PubMed PMID: 21621699.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - What, how, and how much should patients with burns be fed? AU - Williams,Felicia N, AU - Branski,Ludwik K, AU - Jeschke,Marc G, AU - Herndon,David N, PY - 2011/5/31/entrez PY - 2011/5/31/pubmed PY - 2011/8/13/medline SP - 609 EP - 29 JF - The Surgical clinics of North America JO - Surg. Clin. North Am. VL - 91 IS - 3 N2 - The hypermetabolic response to severe burn injury is characterized by hyperdynamic circulation and profound metabolic, physiologic, catabolic, and immune system derangements. Failure to satisfy overwhelming energy and protein requirements after, and during, severe burn injury results in multiorgan dysfunction, increased susceptibility to infection, and death. Attenuation of the hypermetabolic response by various pharmacologic modalities is emerging as an essential component of the management of patients with severe burn injury. This review focuses on the more recent advances in therapeutic strategies to attenuate the hypermetabolic response and its postburn-associated insulin resistance. SN - 1558-3171 UR - https://www.unboundmedicine.com/medline/citation/21621699/full_citation L2 - https://linkinghub.elsevier.com/retrieve/pii/S0039-6109(11)00031-4 DB - PRIME DP - Unbound Medicine ER -