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[Opioid analgesics in patients with chronic renal failure: principles for use and current guidelines].
G Ital Nefrol. 2011 May-Jun; 28(3):269-77.GI

Abstract

The treatment of pain in patients with impaired renal function may be problematic, especially when opioid drugs need to be used. In the presence of renal failure, significant changes occur in the metabolism and pharmacokinetics of these drugs, which can lead to adverse reactions due to the accumulation of parental compounds and active metabolites. This paper presents and discusses the available evidence concerning the optimal use of the most frequently employed opioid analgesics to treat pain in patients with renal impairment.

Authors+Show Affiliations

Unita' Operativa di Ematologia, Ospedale S. Eugenio, Roma, Italy.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

ita

PubMed ID

21626495

Citation

Niscola, Pasquale, et al. "[Opioid Analgesics in Patients With Chronic Renal Failure: Principles for Use and Current Guidelines]." Giornale Italiano Di Nefrologia : Organo Ufficiale Della Societa Italiana Di Nefrologia, vol. 28, no. 3, 2011, pp. 269-77.
Niscola P, Giovannini M, Vischini G, et al. [Opioid analgesics in patients with chronic renal failure: principles for use and current guidelines]. G Ital Nefrol. 2011;28(3):269-77.
Niscola, P., Giovannini, M., Vischini, G., Scaramucci, L., Ferrannini, M., Tendas, A., Cupelli, L., Bondanini, F., Di Daniele, N., & Palumbo, R. (2011). [Opioid analgesics in patients with chronic renal failure: principles for use and current guidelines]. Giornale Italiano Di Nefrologia : Organo Ufficiale Della Societa Italiana Di Nefrologia, 28(3), 269-77.
Niscola P, et al. [Opioid Analgesics in Patients With Chronic Renal Failure: Principles for Use and Current Guidelines]. G Ital Nefrol. 2011 May-Jun;28(3):269-77. PubMed PMID: 21626495.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Opioid analgesics in patients with chronic renal failure: principles for use and current guidelines]. AU - Niscola,Pasquale, AU - Giovannini,Marco, AU - Vischini,Gisella, AU - Scaramucci,Laura, AU - Ferrannini,Michele, AU - Tendas,Andrea, AU - Cupelli,Luca, AU - Bondanini,Francesco, AU - Di Daniele,Nicola, AU - Palumbo,Roberto, PY - 2011/6/1/entrez PY - 2011/6/1/pubmed PY - 2011/8/4/medline SP - 269 EP - 77 JF - Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia JO - G Ital Nefrol VL - 28 IS - 3 N2 - The treatment of pain in patients with impaired renal function may be problematic, especially when opioid drugs need to be used. In the presence of renal failure, significant changes occur in the metabolism and pharmacokinetics of these drugs, which can lead to adverse reactions due to the accumulation of parental compounds and active metabolites. This paper presents and discusses the available evidence concerning the optimal use of the most frequently employed opioid analgesics to treat pain in patients with renal impairment. SN - 0393-5590 UR - https://www.unboundmedicine.com/medline/citation/21626495/[Opioid_analgesics_in_patients_with_chronic_renal_failure:_principles_for_use_and_current_guidelines]_ L2 - https://medlineplus.gov/kidneyfailure.html DB - PRIME DP - Unbound Medicine ER -