Tags

Type your tag names separated by a space and hit enter

Effect of simultaneous consumption of milk and coffee on chlorogenic acids' bioavailability in humans.
J Agric Food Chem. 2011 Jul 27; 59(14):7925-31.JA

Abstract

Different studies have shown that milk may interact with polyphenols and affect their bioavailability in humans. The present study investigated the effect of the simultaneous consumption of coffee and milk on the urinary excretion of chlorogenic acids (CGA) and metabolites. Subjects were submitted to consumption of water, instant coffee (609 mmol of CGA) dissolved in water, and instant coffee dissolved in whole milk. Urine was collected for 24 h after consumption of each treatment for analysis of CGA and metabolites by HPLC/LC-MS. The amount of CGA and metabolites recovered after consumption of combined coffee-milk (40% ± 27%) was consistently lower in all subjects compared to that of coffee alone (68% ± 20%). Concluding, the simultaneous consumption of milk and coffee may impair the bioavailability of coffee CGA in humans.

Authors+Show Affiliations

Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.No affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21627318

Citation

Duarte, Giselle S., and Adriana Farah. "Effect of Simultaneous Consumption of Milk and Coffee On Chlorogenic Acids' Bioavailability in Humans." Journal of Agricultural and Food Chemistry, vol. 59, no. 14, 2011, pp. 7925-31.
Duarte GS, Farah A. Effect of simultaneous consumption of milk and coffee on chlorogenic acids' bioavailability in humans. J Agric Food Chem. 2011;59(14):7925-31.
Duarte, G. S., & Farah, A. (2011). Effect of simultaneous consumption of milk and coffee on chlorogenic acids' bioavailability in humans. Journal of Agricultural and Food Chemistry, 59(14), 7925-31. https://doi.org/10.1021/jf201906p
Duarte GS, Farah A. Effect of Simultaneous Consumption of Milk and Coffee On Chlorogenic Acids' Bioavailability in Humans. J Agric Food Chem. 2011 Jul 27;59(14):7925-31. PubMed PMID: 21627318.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of simultaneous consumption of milk and coffee on chlorogenic acids' bioavailability in humans. AU - Duarte,Giselle S, AU - Farah,Adriana, Y1 - 2011/06/15/ PY - 2011/6/2/entrez PY - 2011/6/2/pubmed PY - 2011/11/11/medline SP - 7925 EP - 31 JF - Journal of agricultural and food chemistry JO - J Agric Food Chem VL - 59 IS - 14 N2 - Different studies have shown that milk may interact with polyphenols and affect their bioavailability in humans. The present study investigated the effect of the simultaneous consumption of coffee and milk on the urinary excretion of chlorogenic acids (CGA) and metabolites. Subjects were submitted to consumption of water, instant coffee (609 mmol of CGA) dissolved in water, and instant coffee dissolved in whole milk. Urine was collected for 24 h after consumption of each treatment for analysis of CGA and metabolites by HPLC/LC-MS. The amount of CGA and metabolites recovered after consumption of combined coffee-milk (40% ± 27%) was consistently lower in all subjects compared to that of coffee alone (68% ± 20%). Concluding, the simultaneous consumption of milk and coffee may impair the bioavailability of coffee CGA in humans. SN - 1520-5118 UR - https://www.unboundmedicine.com/medline/citation/21627318/Effect_of_simultaneous_consumption_of_milk_and_coffee_on_chlorogenic_acids'_bioavailability_in_humans_ L2 - https://doi.org/10.1021/jf201906p DB - PRIME DP - Unbound Medicine ER -