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Evaluation of self-treatment of mild-to-moderate facial acne with a blue light treatment system.

Abstract

INTRODUCTION

This study evaluated the efficacy and tolerability of treating mild-to-moderate facial acne using a new, hand-held, light-emitting diode blue light device in conjunction with a foam cleanser containing 5% glycolic acid and 2% salicylic acid plus a skin rebuilding serum containing 1.25% salicylic acid, 0.5% niacinamide, 0.08% liposomal-based azelaic acid and superoxide dismutase.

METHODS

Volunteers with mild-to-moderate facial inflammatory acne used the blue light device twice daily for eight weeks, plus the cleanser before treatments and the serum after each evening treatment.

RESULTS

Among 33 subjects aged 25-45 years old, 28 completed. In a 3 cm x 5 cm target area receiving a daily dose of ~29 J/cm2, treatment was associated with significant reductions from baseline in the inflammatory lesion count from week 1 onward (P≤ .01) and in the non-inflammatory lesion count from week 4 onward (P≤ .05). The number of flares was significantly reduced from baseline from week 2 onward (P≤ .05), and flare severity and flare redness were significantly reduced from baseline from week 4 onward (P≤ .01 and P≤ .05, respectively). At week 8, more than 90 percent of subjects reported improvements in their skin's overall appearance, clarity, radiance, tone, texture and smoothness. In addition, 82 percent were satisfied, very satisfied, or extremely satisfied with the blue light treatment system and 86 percent agreed the treatment system was much gentler than traditional acne treatments.

CONCLUSION

The blue light treatment system offers effective, rapid, convenient and well tolerated treatment of inflammatory and non-inflammatory acne lesions. The majority of subjects consider it much gentler than traditional acne treatments and it facilitates effective treatment without the need for antibiotic exposure. The blue light treatment system and blue light therapy alone are attractive treatment options for acne vulgaris, both as alternatives to traditional acne treatments and as adjunctive treatments to complement existing therapies.

Links

Authors+Show Affiliations

,

Department of Dermatology, University of Missouri Healthcare, 1 Hospital Drive, Columbia, MO 65212, USA. wheelandr@health.missouri.edu

Source

Journal of drugs in dermatology : JDD 10:6 2011 Jun pg 596-602

MeSH

Acne Vulgaris
Adult
Combined Modality Therapy
Dermatologic Agents
Dicarboxylic Acids
Drug Combinations
Female
Glycolates
Humans
Inflammation
Male
Middle Aged
Niacinamide
Patient Satisfaction
Phototherapy
Salicylic Acid
Severity of Illness Index
Superoxide Dismutase
Treatment Outcome

Pub Type(s)

Clinical Trial
Journal Article

Language

eng

PubMed ID

21637900

Citation

TY - JOUR T1 - Evaluation of self-treatment of mild-to-moderate facial acne with a blue light treatment system. AU - Wheeland,Ronald G, AU - Dhawan,Sunil, PY - 2011/6/4/entrez PY - 2011/6/4/pubmed PY - 2011/10/4/medline SP - 596 EP - 602 JF - Journal of drugs in dermatology : JDD JO - J Drugs Dermatol VL - 10 IS - 6 N2 - INTRODUCTION: This study evaluated the efficacy and tolerability of treating mild-to-moderate facial acne using a new, hand-held, light-emitting diode blue light device in conjunction with a foam cleanser containing 5% glycolic acid and 2% salicylic acid plus a skin rebuilding serum containing 1.25% salicylic acid, 0.5% niacinamide, 0.08% liposomal-based azelaic acid and superoxide dismutase. METHODS: Volunteers with mild-to-moderate facial inflammatory acne used the blue light device twice daily for eight weeks, plus the cleanser before treatments and the serum after each evening treatment. RESULTS: Among 33 subjects aged 25-45 years old, 28 completed. In a 3 cm x 5 cm target area receiving a daily dose of ~29 J/cm2, treatment was associated with significant reductions from baseline in the inflammatory lesion count from week 1 onward (P≤ .01) and in the non-inflammatory lesion count from week 4 onward (P≤ .05). The number of flares was significantly reduced from baseline from week 2 onward (P≤ .05), and flare severity and flare redness were significantly reduced from baseline from week 4 onward (P≤ .01 and P≤ .05, respectively). At week 8, more than 90 percent of subjects reported improvements in their skin's overall appearance, clarity, radiance, tone, texture and smoothness. In addition, 82 percent were satisfied, very satisfied, or extremely satisfied with the blue light treatment system and 86 percent agreed the treatment system was much gentler than traditional acne treatments. CONCLUSION: The blue light treatment system offers effective, rapid, convenient and well tolerated treatment of inflammatory and non-inflammatory acne lesions. The majority of subjects consider it much gentler than traditional acne treatments and it facilitates effective treatment without the need for antibiotic exposure. The blue light treatment system and blue light therapy alone are attractive treatment options for acne vulgaris, both as alternatives to traditional acne treatments and as adjunctive treatments to complement existing therapies. SN - 1545-9616 UR - https://www.unboundmedicine.com/medline/citation/21637900/abstract/Evaluation_of_Self_Treatment_of_Mild_to_Moderate_Facial_Acne_with_a_Blue_Light_Treatment_System_ L2 - https://medlineplus.gov/acne.html ER -