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Simultaneous diagnosis of acute lymphoblastic leukemia and peripheral neuroblastic tumor in a child.
J Pediatr Hematol Oncol 2012; 34(1):72-5JP

Abstract

We report the case of a 3-year-old girl with a mediastinal mass, severe anemia, leukocytosis and neutropenia, in whom, after initial suspicion of metastatic neuroblastoma, a final diagnosis of concurrent ganglioneuroblastoma and acute lymphoblastic leukemia was made. The mediastinal tumor was surgically excised and the child subsequently underwent chemotherapy for acute lymphoblastic leukemia. The patient remains in complete remission from both diseases 4 years after the diagnosis and 24 months after completion of all treatment. The simultaneous occurrence of 2 different neoplasms in a child is very infrequent, and no comparable cases are reported in the literature.

Authors+Show Affiliations

Pediatric Hematology and Oncology Unit, G. Di Cristina Children's Hospital, A.R.N.A.S. Ospedale Civico, Palermo, Italy. oncoematoped@ospedalecivicopa.orgNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

21646915

Citation

D'angelo, Paolo, et al. "Simultaneous Diagnosis of Acute Lymphoblastic Leukemia and Peripheral Neuroblastic Tumor in a Child." Journal of Pediatric Hematology/oncology, vol. 34, no. 1, 2012, pp. 72-5.
D'angelo P, Grigoli A, Sementa AR, et al. Simultaneous diagnosis of acute lymphoblastic leukemia and peripheral neuroblastic tumor in a child. J Pediatr Hematol Oncol. 2012;34(1):72-5.
D'angelo, P., Grigoli, A., Sementa, A. R., Tropia, S., Alaggio, R., & Aricò, M. (2012). Simultaneous diagnosis of acute lymphoblastic leukemia and peripheral neuroblastic tumor in a child. Journal of Pediatric Hematology/oncology, 34(1), pp. 72-5. doi:10.1097/MPH.0b013e31820db67b.
D'angelo P, et al. Simultaneous Diagnosis of Acute Lymphoblastic Leukemia and Peripheral Neuroblastic Tumor in a Child. J Pediatr Hematol Oncol. 2012;34(1):72-5. PubMed PMID: 21646915.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Simultaneous diagnosis of acute lymphoblastic leukemia and peripheral neuroblastic tumor in a child. AU - D'angelo,Paolo, AU - Grigoli,Antonella, AU - Sementa,Angela Rita, AU - Tropia,Serena, AU - Alaggio,Rita, AU - Aricò,Maurizio, PY - 2011/6/8/entrez PY - 2011/6/8/pubmed PY - 2012/2/22/medline SP - 72 EP - 5 JF - Journal of pediatric hematology/oncology JO - J. Pediatr. Hematol. Oncol. VL - 34 IS - 1 N2 - We report the case of a 3-year-old girl with a mediastinal mass, severe anemia, leukocytosis and neutropenia, in whom, after initial suspicion of metastatic neuroblastoma, a final diagnosis of concurrent ganglioneuroblastoma and acute lymphoblastic leukemia was made. The mediastinal tumor was surgically excised and the child subsequently underwent chemotherapy for acute lymphoblastic leukemia. The patient remains in complete remission from both diseases 4 years after the diagnosis and 24 months after completion of all treatment. The simultaneous occurrence of 2 different neoplasms in a child is very infrequent, and no comparable cases are reported in the literature. SN - 1536-3678 UR - https://www.unboundmedicine.com/medline/citation/21646915/Simultaneous_diagnosis_of_acute_lymphoblastic_leukemia_and_peripheral_neuroblastic_tumor_in_a_child_ L2 - http://Insights.ovid.com/pubmed?pmid=21646915 DB - PRIME DP - Unbound Medicine ER -