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Plasma selenium, zinc, copper and lipid levels in postmenopausal Turkish women and their relation with osteoporosis.
Biol Trace Elem Res. 2011 Dec; 144(1-3):407-17.BT

Abstract

It has been shown that the trace elements and lipids play role in the growth, development and maintenance of bones. We aimed to investigate serum selenium (Se), zinc (Zn), copper (Cu) and lipid (total cholesterol, triglyceride (TG), high density lipoprotein-cholesterol, low-density lipoprotein-cholesterol) levels in postmenopausal women with osteoporosis, osteopenia and in healthy controls, and to determine the relationship between Se, Zn, Cu and lipid parameters and bone mineral density (BMD). The study included 107 postmenopausal women; 35 healthy (group 1), 37 osteopenic (group 2) and 35 osteoporotic (group 3). The women in all three groups were carefully matched for body mass index (BMI). Serum concentrations of Se, Zn and Cu were measured by atomic absorption spectrophotometry. Plasma Se, Cu, Zn and lipid levels were similar in all groups (p > 0.05). When we combined the women in each of the three groups, and considered them as one group (n = 107) we found a positive correlation between BMI and lumbar vertebra BMD, femur neck BMD, femur total BMD; a positive correlation between TG and femur neck BMD, femur total BMD; a positive correlation between Zn and lumbar vertebra BMD (total T score) (p < 0.05). There was no correlation between Se, Cu, Zn, P and lipid parameters (p > 0.05). Although BMI has a positive effect on BMD, trace elements and lipids, except Zn and TG, did not directly and correlatively influence BMD. Further studies are needed to clarify the role and relationship of trace elements and lipid parameters in postmenopausal osteoporosis.

Authors+Show Affiliations

Department of Obstetrics and Gynecology, Kahramanmaras Sutcu Imam University Medical Faculty, Kahramanmaras, Turkey. drdenizarikan@hotmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21656042

Citation

Arikan, Deniz Cemgil, et al. "Plasma Selenium, Zinc, Copper and Lipid Levels in Postmenopausal Turkish Women and Their Relation With Osteoporosis." Biological Trace Element Research, vol. 144, no. 1-3, 2011, pp. 407-17.
Arikan DC, Coskun A, Ozer A, et al. Plasma selenium, zinc, copper and lipid levels in postmenopausal Turkish women and their relation with osteoporosis. Biol Trace Elem Res. 2011;144(1-3):407-17.
Arikan, D. C., Coskun, A., Ozer, A., Kilinc, M., Atalay, F., & Arikan, T. (2011). Plasma selenium, zinc, copper and lipid levels in postmenopausal Turkish women and their relation with osteoporosis. Biological Trace Element Research, 144(1-3), 407-17. https://doi.org/10.1007/s12011-011-9109-7
Arikan DC, et al. Plasma Selenium, Zinc, Copper and Lipid Levels in Postmenopausal Turkish Women and Their Relation With Osteoporosis. Biol Trace Elem Res. 2011;144(1-3):407-17. PubMed PMID: 21656042.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Plasma selenium, zinc, copper and lipid levels in postmenopausal Turkish women and their relation with osteoporosis. AU - Arikan,Deniz Cemgil, AU - Coskun,Ayhan, AU - Ozer,Ali, AU - Kilinc,Metin, AU - Atalay,Filiz, AU - Arikan,Tugba, Y1 - 2011/06/08/ PY - 2011/05/25/received PY - 2011/06/01/accepted PY - 2011/6/10/entrez PY - 2011/6/10/pubmed PY - 2012/4/28/medline SP - 407 EP - 17 JF - Biological trace element research JO - Biol Trace Elem Res VL - 144 IS - 1-3 N2 - It has been shown that the trace elements and lipids play role in the growth, development and maintenance of bones. We aimed to investigate serum selenium (Se), zinc (Zn), copper (Cu) and lipid (total cholesterol, triglyceride (TG), high density lipoprotein-cholesterol, low-density lipoprotein-cholesterol) levels in postmenopausal women with osteoporosis, osteopenia and in healthy controls, and to determine the relationship between Se, Zn, Cu and lipid parameters and bone mineral density (BMD). The study included 107 postmenopausal women; 35 healthy (group 1), 37 osteopenic (group 2) and 35 osteoporotic (group 3). The women in all three groups were carefully matched for body mass index (BMI). Serum concentrations of Se, Zn and Cu were measured by atomic absorption spectrophotometry. Plasma Se, Cu, Zn and lipid levels were similar in all groups (p > 0.05). When we combined the women in each of the three groups, and considered them as one group (n = 107) we found a positive correlation between BMI and lumbar vertebra BMD, femur neck BMD, femur total BMD; a positive correlation between TG and femur neck BMD, femur total BMD; a positive correlation between Zn and lumbar vertebra BMD (total T score) (p < 0.05). There was no correlation between Se, Cu, Zn, P and lipid parameters (p > 0.05). Although BMI has a positive effect on BMD, trace elements and lipids, except Zn and TG, did not directly and correlatively influence BMD. Further studies are needed to clarify the role and relationship of trace elements and lipid parameters in postmenopausal osteoporosis. SN - 1559-0720 UR - https://www.unboundmedicine.com/medline/citation/21656042/Plasma_selenium_zinc_copper_and_lipid_levels_in_postmenopausal_Turkish_women_and_their_relation_with_osteoporosis_ L2 - https://dx.doi.org/10.1007/s12011-011-9109-7 DB - PRIME DP - Unbound Medicine ER -