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Selective arterial stimulation of secretin in localization of gastrinomas.
Surg Gynecol Obstet. 1990 Sep; 171(3):196-200.SG

Abstract

In two patients with malignant gastrinoma and the Zollinger-Ellison syndrome, we were able to use selective arterial stimulation with secretin as a technique to localize the lesions accurately, allowing resection. The technique of selected arterial secretin stimulation is one of measuring variations in gastrin levels in both the hepatic vein and a peripheral artery at specified times after injection of secretin into a specific artery. When the criteria for localization have been met, one can plot the presence of the gastrinoma within the blood supply of the injected artery and, using angiograms, thus accurately localize the lesion. This method promises to be a valuable additional tumor-localizing procedure, particularly when gastrinomas are extrapancreatic.

Authors+Show Affiliations

Department of Radiology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania 19107.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

2166970

Citation

Rosato, F E., et al. "Selective Arterial Stimulation of Secretin in Localization of Gastrinomas." Surgery, Gynecology & Obstetrics, vol. 171, no. 3, 1990, pp. 196-200.
Rosato FE, Bonn J, Shapiro M, et al. Selective arterial stimulation of secretin in localization of gastrinomas. Surg Gynecol Obstet. 1990;171(3):196-200.
Rosato, F. E., Bonn, J., Shapiro, M., BarBot, D. J., Furnary, A. M., & Gardiner, G. A. (1990). Selective arterial stimulation of secretin in localization of gastrinomas. Surgery, Gynecology & Obstetrics, 171(3), 196-200.
Rosato FE, et al. Selective Arterial Stimulation of Secretin in Localization of Gastrinomas. Surg Gynecol Obstet. 1990;171(3):196-200. PubMed PMID: 2166970.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Selective arterial stimulation of secretin in localization of gastrinomas. AU - Rosato,F E, AU - Bonn,J, AU - Shapiro,M, AU - BarBot,D J, AU - Furnary,A M, AU - Gardiner,G A, PY - 1990/9/1/pubmed PY - 1990/9/1/medline PY - 1990/9/1/entrez SP - 196 EP - 200 JF - Surgery, gynecology & obstetrics JO - Surg Gynecol Obstet VL - 171 IS - 3 N2 - In two patients with malignant gastrinoma and the Zollinger-Ellison syndrome, we were able to use selective arterial stimulation with secretin as a technique to localize the lesions accurately, allowing resection. The technique of selected arterial secretin stimulation is one of measuring variations in gastrin levels in both the hepatic vein and a peripheral artery at specified times after injection of secretin into a specific artery. When the criteria for localization have been met, one can plot the presence of the gastrinoma within the blood supply of the injected artery and, using angiograms, thus accurately localize the lesion. This method promises to be a valuable additional tumor-localizing procedure, particularly when gastrinomas are extrapancreatic. SN - 0039-6087 UR - https://www.unboundmedicine.com/medline/citation/2166970/Selective_arterial_stimulation_of_secretin_in_localization_of_gastrinomas_ L2 - https://medlineplus.gov/pancreaticcancer.html DB - PRIME DP - Unbound Medicine ER -