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[A study of traditional Chinese medicine syndromes correlated to neurologic function or to coagulation function in patients with acute cerebral infarction].
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2011 Jun; 23(6):329-32.ZW

Abstract

OBJECTIVE

To investigate the correlations between traditional Chinese medicine (TCM) syndrome elements and neurologic function and between them and coagulation function in patients with acute cerebral infarction (ACI).

METHODS

Two hundred and twenty-three patients with ACI were enrolled. The syndromes of this disease were scored according to Stroke Diagnostic Criteria for Differentiation of Syndromes. Neurologic function deficit score (NDS) was scored according to stroke scale of the National Institutes of Health (NIHSS). The prothrombin time (PT), activated partial thromboplastin time (APTT) and fibrinogen (FIB) contents were detected. The correlations between TCM syndrome elements and NDS and between them and coagulation function were investigated.

RESULTS

Two hundred and twenty-three patients with ACI were divided into six syndromes: wind syndrome (n=147, 65.92%), fire syndrome (n=100, 44.84%), tan syndrome (n=123, 55.16%), blood stasis syndrome (n=78, 34.98%), deficiency of qi syndrome (n=31, 13.90%), and yin deficiency causing hyperactivity of yang syndrome (n=25, 11.21%). The wind, tan and fire syndromes were the main syndrome elements related to ACI. The scores of wind, fire, tan and deficiency of qi syndromes were positively related to NDS (r₁=0.207, P₁=0.002; r₂=0.284, P₂=0.000; r₃=0.245, P₃=0.000; r₄=0.152, P₄=0.023). The score of deficiency of qi syndrome was negatively correlated with PT (r=-0.170, P=0.011); and the scores of tan, blood stasis, and deficiency of qi syndromes were negatively correlated with APTT (r₁=-0.182, P₁=0.006; r₂=-0.148, P₂=0.027; r₃=-0.211, P₃=0.001).Other syndromes were not correlated to NDS or coagulation factors.

CONCLUSION

The neurologic function deficiency due to ACI is more likely influenced by wind, tan, and fire syndromes; deficiency of qi syndrome also has some effects. The syndromes of tan, blood stasis, and deficiency of qi are closely correlated with coagulation function, and their scores may reflect the clotting function in patients with ACI.

Authors+Show Affiliations

Department of Traditional Chinese Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China. lj7357@vip.sina.comNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

21672378

Citation

Li, Jing, et al. "[A Study of Traditional Chinese Medicine Syndromes Correlated to Neurologic Function or to Coagulation Function in Patients With Acute Cerebral Infarction]." Zhongguo Wei Zhong Bing Ji Jiu Yi Xue = Chinese Critical Care Medicine = Zhongguo Weizhongbing Jijiuyixue, vol. 23, no. 6, 2011, pp. 329-32.
Li J, Cao R, Zhu HX, et al. [A study of traditional Chinese medicine syndromes correlated to neurologic function or to coagulation function in patients with acute cerebral infarction]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2011;23(6):329-32.
Li, J., Cao, R., Zhu, H. X., & Hu, W. Z. (2011). [A study of traditional Chinese medicine syndromes correlated to neurologic function or to coagulation function in patients with acute cerebral infarction]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue = Chinese Critical Care Medicine = Zhongguo Weizhongbing Jijiuyixue, 23(6), 329-32.
Li J, et al. [A Study of Traditional Chinese Medicine Syndromes Correlated to Neurologic Function or to Coagulation Function in Patients With Acute Cerebral Infarction]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2011;23(6):329-32. PubMed PMID: 21672378.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [A study of traditional Chinese medicine syndromes correlated to neurologic function or to coagulation function in patients with acute cerebral infarction]. AU - Li,Jing, AU - Cao,Rui, AU - Zhu,Hong-xun, AU - Hu,Wen-zhong, PY - 2011/6/16/entrez PY - 2011/6/16/pubmed PY - 2012/1/31/medline SP - 329 EP - 32 JF - Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue JO - Zhongguo Wei Zhong Bing Ji Jiu Yi Xue VL - 23 IS - 6 N2 - OBJECTIVE: To investigate the correlations between traditional Chinese medicine (TCM) syndrome elements and neurologic function and between them and coagulation function in patients with acute cerebral infarction (ACI). METHODS: Two hundred and twenty-three patients with ACI were enrolled. The syndromes of this disease were scored according to Stroke Diagnostic Criteria for Differentiation of Syndromes. Neurologic function deficit score (NDS) was scored according to stroke scale of the National Institutes of Health (NIHSS). The prothrombin time (PT), activated partial thromboplastin time (APTT) and fibrinogen (FIB) contents were detected. The correlations between TCM syndrome elements and NDS and between them and coagulation function were investigated. RESULTS: Two hundred and twenty-three patients with ACI were divided into six syndromes: wind syndrome (n=147, 65.92%), fire syndrome (n=100, 44.84%), tan syndrome (n=123, 55.16%), blood stasis syndrome (n=78, 34.98%), deficiency of qi syndrome (n=31, 13.90%), and yin deficiency causing hyperactivity of yang syndrome (n=25, 11.21%). The wind, tan and fire syndromes were the main syndrome elements related to ACI. The scores of wind, fire, tan and deficiency of qi syndromes were positively related to NDS (r₁=0.207, P₁=0.002; r₂=0.284, P₂=0.000; r₃=0.245, P₃=0.000; r₄=0.152, P₄=0.023). The score of deficiency of qi syndrome was negatively correlated with PT (r=-0.170, P=0.011); and the scores of tan, blood stasis, and deficiency of qi syndromes were negatively correlated with APTT (r₁=-0.182, P₁=0.006; r₂=-0.148, P₂=0.027; r₃=-0.211, P₃=0.001).Other syndromes were not correlated to NDS or coagulation factors. CONCLUSION: The neurologic function deficiency due to ACI is more likely influenced by wind, tan, and fire syndromes; deficiency of qi syndrome also has some effects. The syndromes of tan, blood stasis, and deficiency of qi are closely correlated with coagulation function, and their scores may reflect the clotting function in patients with ACI. SN - 1003-0603 UR - https://www.unboundmedicine.com/medline/citation/21672378/[A_study_of_traditional_Chinese_medicine_syndromes_correlated_to_neurologic_function_or_to_coagulation_function_in_patients_with_acute_cerebral_infarction]_ DB - PRIME DP - Unbound Medicine ER -