Tags

Type your tag names separated by a space and hit enter

Calcium, vitamin D and cardiovascular disease.
Kidney Blood Press Res. 2011; 34(6):404-17.KB

Abstract

The relationship between calcium and cardiovascular diseases (CVD) has been explored for a long time. Studies exploring the effect of calcium intake or calcium supplementation on cardiovascular risk suggest that systolic blood pressure increases under low calcium intake and decreases with calcium supplementation. A lower calcium intake has been associated with an increased risk of stroke. However, the impact of calcium supplementation on stroke risk remains unclear. Calcium supplementation may increase the risk of myocardial infarction. The relationship between vitamin D and CVD has been explored more recently. Negative correlations between vitamin D levels and the risk of hypertension, myocardial infarction, and stroke have been reported in several observational studies. The effect of vitamin D supplementation on blood pressure is still unclear and no effect of vitamin D supplementation on coronary heart disease or stroke has been clearly demonstrated. There is a lack of randomized clinical trials primarily addressing the effect of these parameters on CVD. Therefore, the real impact of calcium and vitamin D on cardiovascular outcomes remains to be documented by appropriate experimental data.

Authors+Show Affiliations

Unit of Population Epidemiology, Division of Primary Care Medicine, Department of Community Medicine, Primary Care and Emergency Medicine, Geneva University Hospitals, Geneva, Switzerland. idris.guessous@chuv.chNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

21677437

Citation

Guessous, Idris, et al. "Calcium, Vitamin D and Cardiovascular Disease." Kidney & Blood Pressure Research, vol. 34, no. 6, 2011, pp. 404-17.
Guessous I, Bochud M, Bonny O, et al. Calcium, vitamin D and cardiovascular disease. Kidney Blood Press Res. 2011;34(6):404-17.
Guessous, I., Bochud, M., Bonny, O., & Burnier, M. (2011). Calcium, vitamin D and cardiovascular disease. Kidney & Blood Pressure Research, 34(6), 404-17. https://doi.org/10.1159/000328332
Guessous I, et al. Calcium, Vitamin D and Cardiovascular Disease. Kidney Blood Press Res. 2011;34(6):404-17. PubMed PMID: 21677437.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Calcium, vitamin D and cardiovascular disease. AU - Guessous,Idris, AU - Bochud,Murielle, AU - Bonny,Olivier, AU - Burnier,Michel, Y1 - 2011/06/11/ PY - 2011/6/17/entrez PY - 2011/6/17/pubmed PY - 2012/8/17/medline SP - 404 EP - 17 JF - Kidney & blood pressure research JO - Kidney Blood Press. Res. VL - 34 IS - 6 N2 - The relationship between calcium and cardiovascular diseases (CVD) has been explored for a long time. Studies exploring the effect of calcium intake or calcium supplementation on cardiovascular risk suggest that systolic blood pressure increases under low calcium intake and decreases with calcium supplementation. A lower calcium intake has been associated with an increased risk of stroke. However, the impact of calcium supplementation on stroke risk remains unclear. Calcium supplementation may increase the risk of myocardial infarction. The relationship between vitamin D and CVD has been explored more recently. Negative correlations between vitamin D levels and the risk of hypertension, myocardial infarction, and stroke have been reported in several observational studies. The effect of vitamin D supplementation on blood pressure is still unclear and no effect of vitamin D supplementation on coronary heart disease or stroke has been clearly demonstrated. There is a lack of randomized clinical trials primarily addressing the effect of these parameters on CVD. Therefore, the real impact of calcium and vitamin D on cardiovascular outcomes remains to be documented by appropriate experimental data. SN - 1423-0143 UR - https://www.unboundmedicine.com/medline/citation/21677437/Calcium_vitamin_D_and_cardiovascular_disease_ L2 - https://www.karger.com?DOI=10.1159/000328332 DB - PRIME DP - Unbound Medicine ER -