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5-year recurrence rates of Mohs micrographic surgery for aggressive and recurrent facial basal cell carcinoma.
Acta Derm Venereol. 2011 Oct; 91(6):689-93.AD

Abstract

Mohs micrographic surgery allows for complete microscopic examination of the surgical margin when treating aggressive and recurrent facial basal cell carcinomas. This leads to the highest cure rates and maximal preservation of healthy tissue. The 5-year recurrence rates of 587 aggressive and/or recurrent facial basal cell carcinomas treated during 1993 to 2003 at our centre were studied retrospectively. The resulting 5-year recurrence rates using Kaplan-Meier survival analysis were 2.1% for primary (previously untreated) tumours, 5.2% for recurrent basal cell carcinomas and 3.3% overall. In total, 87.9% of the tumours required at least two stages of Mohs micrographic surgery. The surgical defect's size after complete excision was, on average, approximately twice the size of the defect after excision of the clinically visible tumour with a 2-3 mm margin. Mohs micro-graphic surgery is underused in Scandinavia despite being the treatment of choice for aggressive and recurrent facial basal cell carcinomas.

Authors+Show Affiliations

Department of Dermatology and Venereology, Sahlgrenska University Hospital, Institute of Clinical Sciences at the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. john.paoli@vgregion.seNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21681360

Citation

Paoli, John, et al. "5-year Recurrence Rates of Mohs Micrographic Surgery for Aggressive and Recurrent Facial Basal Cell Carcinoma." Acta Dermato-venereologica, vol. 91, no. 6, 2011, pp. 689-93.
Paoli J, Daryoni S, Wennberg AM, et al. 5-year recurrence rates of Mohs micrographic surgery for aggressive and recurrent facial basal cell carcinoma. Acta Derm Venereol. 2011;91(6):689-93.
Paoli, J., Daryoni, S., Wennberg, A. M., Mölne, L., Gillstedt, M., Miocic, M., & Stenquist, B. (2011). 5-year recurrence rates of Mohs micrographic surgery for aggressive and recurrent facial basal cell carcinoma. Acta Dermato-venereologica, 91(6), 689-93. https://doi.org/10.2340/00015555-1134
Paoli J, et al. 5-year Recurrence Rates of Mohs Micrographic Surgery for Aggressive and Recurrent Facial Basal Cell Carcinoma. Acta Derm Venereol. 2011;91(6):689-93. PubMed PMID: 21681360.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - 5-year recurrence rates of Mohs micrographic surgery for aggressive and recurrent facial basal cell carcinoma. AU - Paoli,John, AU - Daryoni,Samuel, AU - Wennberg,Ann-Marie, AU - Mölne,Lena, AU - Gillstedt,Martin, AU - Miocic,Marinko, AU - Stenquist,Bo, PY - 2011/6/18/entrez PY - 2011/6/18/pubmed PY - 2012/3/6/medline SP - 689 EP - 93 JF - Acta dermato-venereologica JO - Acta Derm Venereol VL - 91 IS - 6 N2 - Mohs micrographic surgery allows for complete microscopic examination of the surgical margin when treating aggressive and recurrent facial basal cell carcinomas. This leads to the highest cure rates and maximal preservation of healthy tissue. The 5-year recurrence rates of 587 aggressive and/or recurrent facial basal cell carcinomas treated during 1993 to 2003 at our centre were studied retrospectively. The resulting 5-year recurrence rates using Kaplan-Meier survival analysis were 2.1% for primary (previously untreated) tumours, 5.2% for recurrent basal cell carcinomas and 3.3% overall. In total, 87.9% of the tumours required at least two stages of Mohs micrographic surgery. The surgical defect's size after complete excision was, on average, approximately twice the size of the defect after excision of the clinically visible tumour with a 2-3 mm margin. Mohs micro-graphic surgery is underused in Scandinavia despite being the treatment of choice for aggressive and recurrent facial basal cell carcinomas. SN - 1651-2057 UR - https://www.unboundmedicine.com/medline/citation/21681360/5_year_recurrence_rates_of_Mohs_micrographic_surgery_for_aggressive_and_recurrent_facial_basal_cell_carcinoma_ L2 - https://www.medicaljournals.se/acta/content/abstract/10.2340/00015555-1134 DB - PRIME DP - Unbound Medicine ER -