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Thyrotropin-and prolactin--secreting pituitary tumor dissociated hormonal response to bromocriptine.
Zhonghua Yi Xue Za Zhi (Taipei). 1990 Mar; 45(3):191-5.ZY

Abstract

A 41-year-old male with recurrent hyperthyroidism resulting from pituitary tumor was studied. Because of recurrent hyperthyroidism, he had been treated with propylthiouracil for four years and had been operated. At the time of high serum thyroid hormone (T4: 20 micrograms/dl; T3:502 ng/dl), there was also elevated basal serum TSH level (55 microU/ml) which could not be suppressed by exogenous thyroid hormone administration. In addition, the serum TSH showed blunt response to intravenous TRH infusion. An elevated serum prolactin level was also observed (111 ng/ml). After bromocriptine administration (2.5 mg daily), the suppressibility of serum TSH level was found better than that of prolactin level. The existence of a TSH- and PRL-secreting pituitary tumor in this patient exhibited a dissociated hormonal response to low doses of dopaminergic agents.

Authors+Show Affiliations

Department of Medicine, Veterans General Hospital-Taipei, R.O.C.No affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

2168264

Citation

Jap, T S., et al. "Thyrotropin-and Prolactin--secreting Pituitary Tumor Dissociated Hormonal Response to Bromocriptine." Zhonghua Yi Xue Za Zhi = Chinese Medical Journal; Free China Ed, vol. 45, no. 3, 1990, pp. 191-5.
Jap TS, Kwok CF, Ho LT. Thyrotropin-and prolactin--secreting pituitary tumor dissociated hormonal response to bromocriptine. Zhonghua Yi Xue Za Zhi (Taipei). 1990;45(3):191-5.
Jap, T. S., Kwok, C. F., & Ho, L. T. (1990). Thyrotropin-and prolactin--secreting pituitary tumor dissociated hormonal response to bromocriptine. Zhonghua Yi Xue Za Zhi = Chinese Medical Journal; Free China Ed, 45(3), 191-5.
Jap TS, Kwok CF, Ho LT. Thyrotropin-and Prolactin--secreting Pituitary Tumor Dissociated Hormonal Response to Bromocriptine. Zhonghua Yi Xue Za Zhi (Taipei). 1990;45(3):191-5. PubMed PMID: 2168264.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Thyrotropin-and prolactin--secreting pituitary tumor dissociated hormonal response to bromocriptine. AU - Jap,T S, AU - Kwok,C F, AU - Ho,L T, PY - 1990/3/1/pubmed PY - 1990/3/1/medline PY - 1990/3/1/entrez SP - 191 EP - 5 JF - Zhonghua yi xue za zhi = Chinese medical journal; Free China ed JO - Zhonghua Yi Xue Za Zhi (Taipei) VL - 45 IS - 3 N2 - A 41-year-old male with recurrent hyperthyroidism resulting from pituitary tumor was studied. Because of recurrent hyperthyroidism, he had been treated with propylthiouracil for four years and had been operated. At the time of high serum thyroid hormone (T4: 20 micrograms/dl; T3:502 ng/dl), there was also elevated basal serum TSH level (55 microU/ml) which could not be suppressed by exogenous thyroid hormone administration. In addition, the serum TSH showed blunt response to intravenous TRH infusion. An elevated serum prolactin level was also observed (111 ng/ml). After bromocriptine administration (2.5 mg daily), the suppressibility of serum TSH level was found better than that of prolactin level. The existence of a TSH- and PRL-secreting pituitary tumor in this patient exhibited a dissociated hormonal response to low doses of dopaminergic agents. SN - 0578-1337 UR - https://www.unboundmedicine.com/medline/citation/2168264/Thyrotropin_and_prolactin__secreting_pituitary_tumor_dissociated_hormonal_response_to_bromocriptine_ L2 - https://medlineplus.gov/pituitarytumors.html DB - PRIME DP - Unbound Medicine ER -
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