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The technologies used for developing orally disintegrating tablets: a review.
Acta Pharm. 2011 Jun; 61(2):117-39.AP

Abstract

Orally disintegrating tablets (ODTs), also known as fast melts, quick melts, fast disintegrating and orodispersible systems, have the unique property of disintegrating in the mouth in seconds without chewing and the need of water and are thus assumed to improve patient compliance. Conventional methods like direct compression, wet granulation, moulding, spray-drying, freeze-drying and sublimation were used to prepare ODTs. New advanced technologies like Orasolv®, Durasolv®, Wowtab®, Flashtab®, Zydis®, Flashdose®, Oraquick®, Lyoc®, Advatab®, Frosta®, Quick-Disc® and Nanomelt® have been introduced by some pharmaceutical companies for the production of ODTs. The main objective of this review is to give a comprehensive insight into conventional and recent technologies used for the preparation of ODTs.

Authors+Show Affiliations

S. S. D. J. College of Pharmacy, Neminagar, Chandwad, Dist-Nasik, India.No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

21684842

Citation

Badgujar, Bhatu P., and Atish S. Mundada. "The Technologies Used for Developing Orally Disintegrating Tablets: a Review." Acta Pharmaceutica (Zagreb, Croatia), vol. 61, no. 2, 2011, pp. 117-39.
Badgujar BP, Mundada AS. The technologies used for developing orally disintegrating tablets: a review. Acta Pharm. 2011;61(2):117-39.
Badgujar, B. P., & Mundada, A. S. (2011). The technologies used for developing orally disintegrating tablets: a review. Acta Pharmaceutica (Zagreb, Croatia), 61(2), 117-39. https://doi.org/10.2478/v10007-011-0020-8
Badgujar BP, Mundada AS. The Technologies Used for Developing Orally Disintegrating Tablets: a Review. Acta Pharm. 2011;61(2):117-39. PubMed PMID: 21684842.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The technologies used for developing orally disintegrating tablets: a review. AU - Badgujar,Bhatu P, AU - Mundada,Atish S, PY - 2011/6/21/entrez PY - 2011/6/21/pubmed PY - 2011/10/15/medline SP - 117 EP - 39 JF - Acta pharmaceutica (Zagreb, Croatia) JO - Acta Pharm VL - 61 IS - 2 N2 - Orally disintegrating tablets (ODTs), also known as fast melts, quick melts, fast disintegrating and orodispersible systems, have the unique property of disintegrating in the mouth in seconds without chewing and the need of water and are thus assumed to improve patient compliance. Conventional methods like direct compression, wet granulation, moulding, spray-drying, freeze-drying and sublimation were used to prepare ODTs. New advanced technologies like Orasolv®, Durasolv®, Wowtab®, Flashtab®, Zydis®, Flashdose®, Oraquick®, Lyoc®, Advatab®, Frosta®, Quick-Disc® and Nanomelt® have been introduced by some pharmaceutical companies for the production of ODTs. The main objective of this review is to give a comprehensive insight into conventional and recent technologies used for the preparation of ODTs. SN - 1846-9558 UR - https://www.unboundmedicine.com/medline/citation/21684842/The_technologies_used_for_developing_orally_disintegrating_tablets:_a_review_ L2 - https://www.degruyter.com/doi/10.2478/v10007-011-0020-8 DB - PRIME DP - Unbound Medicine ER -