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Peripheral Lewy body pathology in Parkinson's disease and incidental Lewy body disease: four cases.
J Neurol Sci. 2011 Nov 15; 310(1-2):100-6.JN

Abstract

The accumulation of Lewy pathology (LP) within autonomic nervous system tissues has received increased attention recently as a possible induction site for Lewy neurodegeneration and a possible source of biopsy material for biomarkers of early Parkinson's disease (PD). Here, we describe LP accumulation within various tissues involving peripheral autonomic nervous system neurons in three PD cases and one case of incidental Lewy body disease. Findings highlight the value of examining pathology within functional neuroanatomical systems and particularly the importance of Lewy neurites (LNs) in the pathophysiology of PD.

Authors+Show Affiliations

Clinical Neuroanatomy (Center for Clinical Research, Department of Neurology), University of Ulm, 89081 Ulm, Germany. kelly.del-tredici@uni-ulm.deNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21689832

Citation

Del Tredici, Kelly, and John E. Duda. "Peripheral Lewy Body Pathology in Parkinson's Disease and Incidental Lewy Body Disease: Four Cases." Journal of the Neurological Sciences, vol. 310, no. 1-2, 2011, pp. 100-6.
Del Tredici K, Duda JE. Peripheral Lewy body pathology in Parkinson's disease and incidental Lewy body disease: four cases. J Neurol Sci. 2011;310(1-2):100-6.
Del Tredici, K., & Duda, J. E. (2011). Peripheral Lewy body pathology in Parkinson's disease and incidental Lewy body disease: four cases. Journal of the Neurological Sciences, 310(1-2), 100-6. https://doi.org/10.1016/j.jns.2011.06.003
Del Tredici K, Duda JE. Peripheral Lewy Body Pathology in Parkinson's Disease and Incidental Lewy Body Disease: Four Cases. J Neurol Sci. 2011 Nov 15;310(1-2):100-6. PubMed PMID: 21689832.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Peripheral Lewy body pathology in Parkinson's disease and incidental Lewy body disease: four cases. AU - Del Tredici,Kelly, AU - Duda,John E, PY - 2011/03/29/received PY - 2011/05/27/revised PY - 2011/06/01/accepted PY - 2011/6/22/entrez PY - 2011/6/22/pubmed PY - 2012/2/18/medline SP - 100 EP - 6 JF - Journal of the neurological sciences JO - J Neurol Sci VL - 310 IS - 1-2 N2 - The accumulation of Lewy pathology (LP) within autonomic nervous system tissues has received increased attention recently as a possible induction site for Lewy neurodegeneration and a possible source of biopsy material for biomarkers of early Parkinson's disease (PD). Here, we describe LP accumulation within various tissues involving peripheral autonomic nervous system neurons in three PD cases and one case of incidental Lewy body disease. Findings highlight the value of examining pathology within functional neuroanatomical systems and particularly the importance of Lewy neurites (LNs) in the pathophysiology of PD. SN - 1878-5883 UR - https://www.unboundmedicine.com/medline/citation/21689832/Peripheral_Lewy_body_pathology_in_Parkinson's_disease_and_incidental_Lewy_body_disease:_four_cases_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0022-510X(11)00313-3 DB - PRIME DP - Unbound Medicine ER -