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Viruses with more than 1,000 genes: Mamavirus, a new Acanthamoeba polyphaga mimivirus strain, and reannotation of Mimivirus genes.
Genome Biol Evol. 2011; 3:737-42.GB

Abstract

The genome sequence of the Mamavirus, a new Acanthamoeba polyphaga mimivirus strain, is reported. With 1,191,693 nt in length and 1,023 predicted protein-coding genes, the Mamavirus has the largest genome among the known viruses. The genomes of the Mamavirus and the previously described Mimivirus are highly similar in both the protein-coding genes and the intergenic regions. However, the Mamavirus contains an extra 5'-terminal segment that encompasses primarily disrupted duplicates of genes present elsewhere in the genome. The Mamavirus also has several unique genes including a small regulatory polyA polymerase subunit that is shared with poxviruses. Detailed analysis of the protein sequences of the two Mimiviruses led to a substantial amendment of the functional annotation of the viral genomes.

Authors+Show Affiliations

Unité de Recherche sur les Maladies Infectieuses et Tropicales Émergentes (URMITE), Centre National de la Recherche Scientifique UMR IRD 6236, Faculté de Médecine, Université de la Méditerranée, Marseille, France.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Intramural

Language

eng

PubMed ID

21705471

Citation

Colson, Philippe, et al. "Viruses With More Than 1,000 Genes: Mamavirus, a New Acanthamoeba Polyphaga Mimivirus Strain, and Reannotation of Mimivirus Genes." Genome Biology and Evolution, vol. 3, 2011, pp. 737-42.
Colson P, Yutin N, Shabalina SA, et al. Viruses with more than 1,000 genes: Mamavirus, a new Acanthamoeba polyphaga mimivirus strain, and reannotation of Mimivirus genes. Genome Biol Evol. 2011;3:737-42.
Colson, P., Yutin, N., Shabalina, S. A., Robert, C., Fournous, G., La Scola, B., Raoult, D., & Koonin, E. V. (2011). Viruses with more than 1,000 genes: Mamavirus, a new Acanthamoeba polyphaga mimivirus strain, and reannotation of Mimivirus genes. Genome Biology and Evolution, 3, 737-42. https://doi.org/10.1093/gbe/evr048
Colson P, et al. Viruses With More Than 1,000 Genes: Mamavirus, a New Acanthamoeba Polyphaga Mimivirus Strain, and Reannotation of Mimivirus Genes. Genome Biol Evol. 2011;3:737-42. PubMed PMID: 21705471.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Viruses with more than 1,000 genes: Mamavirus, a new Acanthamoeba polyphaga mimivirus strain, and reannotation of Mimivirus genes. AU - Colson,Philippe, AU - Yutin,Natalya, AU - Shabalina,Svetlana A, AU - Robert,Catherine, AU - Fournous,Ghislain, AU - La Scola,Bernard, AU - Raoult,Didier, AU - Koonin,Eugene V, Y1 - 2011/06/24/ PY - 2011/6/28/entrez PY - 2011/6/28/pubmed PY - 2012/2/4/medline SP - 737 EP - 42 JF - Genome biology and evolution JO - Genome Biol Evol VL - 3 N2 - The genome sequence of the Mamavirus, a new Acanthamoeba polyphaga mimivirus strain, is reported. With 1,191,693 nt in length and 1,023 predicted protein-coding genes, the Mamavirus has the largest genome among the known viruses. The genomes of the Mamavirus and the previously described Mimivirus are highly similar in both the protein-coding genes and the intergenic regions. However, the Mamavirus contains an extra 5'-terminal segment that encompasses primarily disrupted duplicates of genes present elsewhere in the genome. The Mamavirus also has several unique genes including a small regulatory polyA polymerase subunit that is shared with poxviruses. Detailed analysis of the protein sequences of the two Mimiviruses led to a substantial amendment of the functional annotation of the viral genomes. SN - 1759-6653 UR - https://www.unboundmedicine.com/medline/citation/21705471/Viruses_with_more_than_1000_genes:_Mamavirus_a_new_Acanthamoeba_polyphaga_mimivirus_strain_and_reannotation_of_Mimivirus_genes_ L2 - https://academic.oup.com/gbe/article-lookup/doi/10.1093/gbe/evr048 DB - PRIME DP - Unbound Medicine ER -