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[Visceral leishmaniasis. Personal observation and review of epidemiology, clinical aspects and therapy].
Klin Padiatr. 1990 Sep-Oct; 202(5):347-51.KP

Abstract

A 5 year old German girl contracted visceral leishmaniasis during a vacation in Spain, either 32 or 20 month prior to the manifestation of disease. She presented with fever, hepatosplenomegaly and pancytopenia. A bone marrow aspirate proved the diagnosis. Therapy with a pentavalent antimony drug brought about immediate improvement. Visceral leishmaniasis has to be suspected in individuals with fever, hepatosplenomegaly and pancytopenia who have resided in endemic areas (Mediterranean countries, India, East Africa, South America) during the previous years. If untreated, visceral leishmaniasis runs a fatal course. Therefore, early diagnosis by morphological and serological means and specific therapy with pentavalent antimony drugs are mandatory.

Authors+Show Affiliations

Dickerhoff R
Universitäts-Kinderklinik, Abteilung Hämatologie/Onkologie.
Müller A
No affiliation info available
Bode U
No affiliation info available

MeSH

AnimalsAntimony Sodium GluconateBone MarrowChild, PreschoolFemaleHepatomegalyHumansLeishmania donovaniLeishmaniasis, VisceralPancytopeniaSplenomegaly

Pub Type(s)

Case Reports
English Abstract
Journal Article
Review

Language

ger

PubMed ID

2170739

Citation

Dickerhoff, R, et al. "[Visceral Leishmaniasis. Personal Observation and Review of Epidemiology, Clinical Aspects and Therapy]." Klinische Padiatrie, vol. 202, no. 5, 1990, pp. 347-51.
Dickerhoff R, Müller A, Bode U. [Visceral leishmaniasis. Personal observation and review of epidemiology, clinical aspects and therapy]. Klin Padiatr. 1990;202(5):347-51.
Dickerhoff, R., Müller, A., & Bode, U. (1990). [Visceral leishmaniasis. Personal observation and review of epidemiology, clinical aspects and therapy]. Klinische Padiatrie, 202(5), 347-51.
Dickerhoff R, Müller A, Bode U. [Visceral Leishmaniasis. Personal Observation and Review of Epidemiology, Clinical Aspects and Therapy]. Klin Padiatr. 1990 Sep-Oct;202(5):347-51. PubMed PMID: 2170739.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Visceral leishmaniasis. Personal observation and review of epidemiology, clinical aspects and therapy]. AU - Dickerhoff,R, AU - Müller,A, AU - Bode,U, PY - 1990/9/1/pubmed PY - 1990/9/1/medline PY - 1990/9/1/entrez SP - 347 EP - 51 JF - Klinische Padiatrie JO - Klin Padiatr VL - 202 IS - 5 N2 - A 5 year old German girl contracted visceral leishmaniasis during a vacation in Spain, either 32 or 20 month prior to the manifestation of disease. She presented with fever, hepatosplenomegaly and pancytopenia. A bone marrow aspirate proved the diagnosis. Therapy with a pentavalent antimony drug brought about immediate improvement. Visceral leishmaniasis has to be suspected in individuals with fever, hepatosplenomegaly and pancytopenia who have resided in endemic areas (Mediterranean countries, India, East Africa, South America) during the previous years. If untreated, visceral leishmaniasis runs a fatal course. Therefore, early diagnosis by morphological and serological means and specific therapy with pentavalent antimony drugs are mandatory. SN - 0300-8630 UR - https://www.unboundmedicine.com/medline/citation/2170739/[Visceral_leishmaniasis__Personal_observation_and_review_of_epidemiology_clinical_aspects_and_therapy]_ DB - PRIME DP - Unbound Medicine ER -