Tags

Type your tag names separated by a space and hit enter

Postprandial lipid responses to an alpha-linolenic acid-rich oil, olive oil and butter in women: a randomized crossover trial.
Lipids Health Dis. 2011 Jun 28; 10:106.LH

Abstract

BACKGROUND

Postprandial lipaemia varies with gender and the composition of dietary fat due to the partitioning of fatty acids between beta-oxidation and incorporation into triacylglycerols (TAGs). Increasing evidence highlights the importance of postprandial measurements to evaluate atherogenic risk. Postprandial effects of alpha-linolenic acid (ALA) in women are poorly characterized. We therefore studied the postprandial lipid response of women to an ALA-rich oil in comparison with olive oil and butter, and characterized the fatty acid composition of total lipids, TAGs, and non-esterified fatty acids (NEFAs) in plasma.

METHODS

A randomized crossover design (n = 19) was used to compare the postprandial effects of 3 meals containing 35 g fat. Blood samples were collected at regular intervals for 7 h. Statistical analysis was carried out with ANOVA (significant difference = P < 0.05).

RESULTS

No significant difference was seen in incremental area under the curve (iAUC) plasma-TAG between the meals. ALA and oleic acid levels were significantly increased in plasma after ALA-rich oil and olive oil meals, respectively. Palmitic acid was significantly increased in plasma-TAG after the butter meal. The ratios of 18:2 n-6 to18:3 n-3 in plasma-TAGs, three and seven hours after the ALA-rich oil meal, were 1.5 and 2.4, respectively. The corresponding values after the olive oil meal were: 13.8 and 16.9; and after the butter meal: 9.0 and 11.6.

CONCLUSIONS

The postprandial p-TAG and NEFA response in healthy pre-menopausal women was not significantly different after the intake of an ALA-rich oil, olive oil and butter. The ALA-rich oil significantly affected different plasma lipid fractions and improved the ratio of n-6 to n-3 fatty acids several hours postprandially.

Authors+Show Affiliations

1Department of Biotechnology, Lund University, P.O. Box 124, SE-22100 Lund, Sweden.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21711508

Citation

Svensson, Julia, et al. "Postprandial Lipid Responses to an Alpha-linolenic Acid-rich Oil, Olive Oil and Butter in Women: a Randomized Crossover Trial." Lipids in Health and Disease, vol. 10, 2011, p. 106.
Svensson J, Rosenquist A, Ohlsson L. Postprandial lipid responses to an alpha-linolenic acid-rich oil, olive oil and butter in women: a randomized crossover trial. Lipids Health Dis. 2011;10:106.
Svensson, J., Rosenquist, A., & Ohlsson, L. (2011). Postprandial lipid responses to an alpha-linolenic acid-rich oil, olive oil and butter in women: a randomized crossover trial. Lipids in Health and Disease, 10, 106. https://doi.org/10.1186/1476-511X-10-106
Svensson J, Rosenquist A, Ohlsson L. Postprandial Lipid Responses to an Alpha-linolenic Acid-rich Oil, Olive Oil and Butter in Women: a Randomized Crossover Trial. Lipids Health Dis. 2011 Jun 28;10:106. PubMed PMID: 21711508.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Postprandial lipid responses to an alpha-linolenic acid-rich oil, olive oil and butter in women: a randomized crossover trial. AU - Svensson,Julia, AU - Rosenquist,Anna, AU - Ohlsson,Lena, Y1 - 2011/06/28/ PY - 2011/05/13/received PY - 2011/06/28/accepted PY - 2011/6/30/entrez PY - 2011/6/30/pubmed PY - 2011/12/13/medline SP - 106 EP - 106 JF - Lipids in health and disease JO - Lipids Health Dis VL - 10 N2 - BACKGROUND: Postprandial lipaemia varies with gender and the composition of dietary fat due to the partitioning of fatty acids between beta-oxidation and incorporation into triacylglycerols (TAGs). Increasing evidence highlights the importance of postprandial measurements to evaluate atherogenic risk. Postprandial effects of alpha-linolenic acid (ALA) in women are poorly characterized. We therefore studied the postprandial lipid response of women to an ALA-rich oil in comparison with olive oil and butter, and characterized the fatty acid composition of total lipids, TAGs, and non-esterified fatty acids (NEFAs) in plasma. METHODS: A randomized crossover design (n = 19) was used to compare the postprandial effects of 3 meals containing 35 g fat. Blood samples were collected at regular intervals for 7 h. Statistical analysis was carried out with ANOVA (significant difference = P < 0.05). RESULTS: No significant difference was seen in incremental area under the curve (iAUC) plasma-TAG between the meals. ALA and oleic acid levels were significantly increased in plasma after ALA-rich oil and olive oil meals, respectively. Palmitic acid was significantly increased in plasma-TAG after the butter meal. The ratios of 18:2 n-6 to18:3 n-3 in plasma-TAGs, three and seven hours after the ALA-rich oil meal, were 1.5 and 2.4, respectively. The corresponding values after the olive oil meal were: 13.8 and 16.9; and after the butter meal: 9.0 and 11.6. CONCLUSIONS: The postprandial p-TAG and NEFA response in healthy pre-menopausal women was not significantly different after the intake of an ALA-rich oil, olive oil and butter. The ALA-rich oil significantly affected different plasma lipid fractions and improved the ratio of n-6 to n-3 fatty acids several hours postprandially. SN - 1476-511X UR - https://www.unboundmedicine.com/medline/citation/21711508/Postprandial_lipid_responses_to_an_alpha_linolenic_acid_rich_oil_olive_oil_and_butter_in_women:_a_randomized_crossover_trial_ L2 - https://lipidworld.biomedcentral.com/articles/10.1186/1476-511X-10-106 DB - PRIME DP - Unbound Medicine ER -