Tags

Type your tag names separated by a space and hit enter

Clinicopathological characteristics of mucinous and non-mucinous adenocarcinoma in the colon and rectum in Rajavithi Hospital, Thailand.
J Med Assoc Thai. 2011 Mar; 94 Suppl 2:S41-5.JM

Abstract

BACKGROUND

The clinicopathological characteristics of colorectal mucinous adenocarcinoma (MA) are still controversial. Most of the reports suggested that MA were associated with worse clinicopathological behavior and poorer prognosis than non-mucinous adenocarcinoma (NMA) while the others showed no difference.

OBJECTIVE

To compare clinicopathological characteristics and tumor recurrence of MA patients with those in NMA patients.

MATERIAL AND METHOD

During the period of 2000 to 2009 in Rajavithi Hospital, a total of 427 colorectal adenocarcinoma patient records consisting of 407 NMA and 20 MA were included in this study. Mean age, tumor location, TNM staging at diagnosis, T-stage, N-stage, preoperative CEA level and recurrent rate of MA patients were compared with those of NMA patients.

RESULTS

The distribution of MA patients for gender, mean age, tumor location, TNM stage and preoperative CEA level were similar to those of NMA patients (all p > 0.05). Only the tumor recurrence in MA was significantly more common than that in NMA (p = 0.020, OR = 3.28 (1.14-9.43)), whereas the TNM stage was not significantly different from NMA (p = 0.530). The metastatic site and pattern of metastasis also showed no statistical significance (p = 0.125).

CONCLUSION

The prognosis of MA is poorer than NMA. This may be associated with mucinous histological type itself.

Authors+Show Affiliations

Department of Surgery, Rajavithi Hospital, College of Medicine, Rangsit University, Bangkok, Thailand. paiboon_jiva@yahoo.co.thNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

21717877

Citation

Jivapaisarnpong, Paiboon, and Kanya Boonthongtho. "Clinicopathological Characteristics of Mucinous and Non-mucinous Adenocarcinoma in the Colon and Rectum in Rajavithi Hospital, Thailand." Journal of the Medical Association of Thailand = Chotmaihet Thangphaet, vol. 94 Suppl 2, 2011, pp. S41-5.
Jivapaisarnpong P, Boonthongtho K. Clinicopathological characteristics of mucinous and non-mucinous adenocarcinoma in the colon and rectum in Rajavithi Hospital, Thailand. J Med Assoc Thai. 2011;94 Suppl 2:S41-5.
Jivapaisarnpong, P., & Boonthongtho, K. (2011). Clinicopathological characteristics of mucinous and non-mucinous adenocarcinoma in the colon and rectum in Rajavithi Hospital, Thailand. Journal of the Medical Association of Thailand = Chotmaihet Thangphaet, 94 Suppl 2, S41-5.
Jivapaisarnpong P, Boonthongtho K. Clinicopathological Characteristics of Mucinous and Non-mucinous Adenocarcinoma in the Colon and Rectum in Rajavithi Hospital, Thailand. J Med Assoc Thai. 2011;94 Suppl 2:S41-5. PubMed PMID: 21717877.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinicopathological characteristics of mucinous and non-mucinous adenocarcinoma in the colon and rectum in Rajavithi Hospital, Thailand. AU - Jivapaisarnpong,Paiboon, AU - Boonthongtho,Kanya, PY - 2011/7/2/entrez PY - 2011/7/2/pubmed PY - 2011/7/20/medline SP - S41 EP - 5 JF - Journal of the Medical Association of Thailand = Chotmaihet thangphaet JO - J Med Assoc Thai VL - 94 Suppl 2 N2 - BACKGROUND: The clinicopathological characteristics of colorectal mucinous adenocarcinoma (MA) are still controversial. Most of the reports suggested that MA were associated with worse clinicopathological behavior and poorer prognosis than non-mucinous adenocarcinoma (NMA) while the others showed no difference. OBJECTIVE: To compare clinicopathological characteristics and tumor recurrence of MA patients with those in NMA patients. MATERIAL AND METHOD: During the period of 2000 to 2009 in Rajavithi Hospital, a total of 427 colorectal adenocarcinoma patient records consisting of 407 NMA and 20 MA were included in this study. Mean age, tumor location, TNM staging at diagnosis, T-stage, N-stage, preoperative CEA level and recurrent rate of MA patients were compared with those of NMA patients. RESULTS: The distribution of MA patients for gender, mean age, tumor location, TNM stage and preoperative CEA level were similar to those of NMA patients (all p > 0.05). Only the tumor recurrence in MA was significantly more common than that in NMA (p = 0.020, OR = 3.28 (1.14-9.43)), whereas the TNM stage was not significantly different from NMA (p = 0.530). The metastatic site and pattern of metastasis also showed no statistical significance (p = 0.125). CONCLUSION: The prognosis of MA is poorer than NMA. This may be associated with mucinous histological type itself. SN - 0125-2208 UR - https://www.unboundmedicine.com/medline/citation/21717877/Clinicopathological_characteristics_of_mucinous_and_non_mucinous_adenocarcinoma_in_the_colon_and_rectum_in_Rajavithi_Hospital_Thailand_ DB - PRIME DP - Unbound Medicine ER -