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Prevalence and effect on health-related quality of life of overactive bladder in older americans: results from the epidemiology of lower urinary tract symptoms study.
J Am Geriatr Soc. 2011 Aug; 59(8):1465-70.JA

Abstract

OBJECTIVE

To evaluate the prevalence and effect of overactive bladder (OAB) on healthcare-seeking behavior, mental health, and generic and condition-specific health-related quality of life (HRQL) in older adults.

DESIGN

Secondary analysis of the U.S. sample of the Epidemiology of Lower Urinary Tract Symptoms (EpiLUTS) study-a population-based, cross-sectional, Internet-based survey.

SETTING

Community.

PARTICIPANTS

Two thousand four hundred eighty-five men and 2,877 women aged 65 and older.

MEASUREMENTS

Prevalence and effect on HRQL of urinary symptoms, including OAB. OAB was defined as the presence of urinary urgency and/or urinary urgency incontinence. Descriptive analyses and subgroup comparisons were conducted to evaluate the prevalence of OAB in men and women aged 65 and older and the effect of OAB on various aspects of HRQL.

RESULTS

The survey response rate was 46.9% of men and 61.0% of women. Prevalence rates of OAB at least "sometimes" were 40.4% in men and 46.9% in women. OAB was associated with significant impairments across all domains of patient-reported outcomes, including general HRQL (Medical Outcomes Study 12-item Short-Form Survey), ratings of anxiety and depression (Hospital Anxiety and Depression Scale), and urinary condition-specific outcomes (Overactive Bladder Questionnaire Short Form and Patient Perception of Bladder Condition) (P<.001).

CONCLUSION

OAB is common in older adults in the United States and is associated with substantial impairment in mental health and HRQL, but rates of treatment seeking behavior are low. Older patients should be assessed for OAB.

Links

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Authors+Show Affiliations

Sexton CC
United BioSource Corporation, Bethesda, Maryland, USA. Chris.Sexton@unitedbiosource.com
Coyne KS
No affiliation info available
Thompson C
No affiliation info available
Bavendam T
No affiliation info available
Chen CI
No affiliation info available
Markland A
No affiliation info available

MeSH

AgedCross-Sectional StudiesFemaleHealth SurveysHumansInternetMaleNocturiaQuality of LifeUnited StatesUrinary Bladder, OveractiveUrinary Incontinence, Urge

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21718275

Clinical Trial Links

BOTOX® at the Time of Prolapse Surgery for OAB

Citation

Sexton, Chris C., et al. "Prevalence and Effect On Health-related Quality of Life of Overactive Bladder in Older Americans: Results From the Epidemiology of Lower Urinary Tract Symptoms Study." Journal of the American Geriatrics Society, vol. 59, no. 8, 2011, pp. 1465-70.
Sexton CC, Coyne KS, Thompson C, et al. Prevalence and effect on health-related quality of life of overactive bladder in older americans: results from the epidemiology of lower urinary tract symptoms study. J Am Geriatr Soc. 2011;59(8):1465-70.
Sexton, C. C., Coyne, K. S., Thompson, C., Bavendam, T., Chen, C. I., & Markland, A. (2011). Prevalence and effect on health-related quality of life of overactive bladder in older americans: results from the epidemiology of lower urinary tract symptoms study. Journal of the American Geriatrics Society, 59(8), 1465-70. https://doi.org/10.1111/j.1532-5415.2011.03492.x
Sexton CC, et al. Prevalence and Effect On Health-related Quality of Life of Overactive Bladder in Older Americans: Results From the Epidemiology of Lower Urinary Tract Symptoms Study. J Am Geriatr Soc. 2011;59(8):1465-70. PubMed PMID: 21718275.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence and effect on health-related quality of life of overactive bladder in older americans: results from the epidemiology of lower urinary tract symptoms study. AU - Sexton,Chris C, AU - Coyne,Karin S, AU - Thompson,Christine, AU - Bavendam,Tamara, AU - Chen,Chieh-I, AU - Markland,Alayne, Y1 - 2011/06/30/ PY - 2011/7/2/entrez PY - 2011/7/2/pubmed PY - 2011/10/25/medline SP - 1465 EP - 70 JF - Journal of the American Geriatrics Society JO - J Am Geriatr Soc VL - 59 IS - 8 N2 - OBJECTIVE: To evaluate the prevalence and effect of overactive bladder (OAB) on healthcare-seeking behavior, mental health, and generic and condition-specific health-related quality of life (HRQL) in older adults. DESIGN: Secondary analysis of the U.S. sample of the Epidemiology of Lower Urinary Tract Symptoms (EpiLUTS) study-a population-based, cross-sectional, Internet-based survey. SETTING: Community. PARTICIPANTS: Two thousand four hundred eighty-five men and 2,877 women aged 65 and older. MEASUREMENTS: Prevalence and effect on HRQL of urinary symptoms, including OAB. OAB was defined as the presence of urinary urgency and/or urinary urgency incontinence. Descriptive analyses and subgroup comparisons were conducted to evaluate the prevalence of OAB in men and women aged 65 and older and the effect of OAB on various aspects of HRQL. RESULTS: The survey response rate was 46.9% of men and 61.0% of women. Prevalence rates of OAB at least "sometimes" were 40.4% in men and 46.9% in women. OAB was associated with significant impairments across all domains of patient-reported outcomes, including general HRQL (Medical Outcomes Study 12-item Short-Form Survey), ratings of anxiety and depression (Hospital Anxiety and Depression Scale), and urinary condition-specific outcomes (Overactive Bladder Questionnaire Short Form and Patient Perception of Bladder Condition) (P<.001). CONCLUSION: OAB is common in older adults in the United States and is associated with substantial impairment in mental health and HRQL, but rates of treatment seeking behavior are low. Older patients should be assessed for OAB. SN - 1532-5415 UR - https://www.unboundmedicine.com/medline/citation/21718275/Prevalence_and_effect_on_health_related_quality_of_life_of_overactive_bladder_in_older_americans:_results_from_the_epidemiology_of_lower_urinary_tract_symptoms_study_ L2 - https://doi.org/10.1111/j.1532-5415.2011.03492.x DB - PRIME DP - Unbound Medicine ER -