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Plant lipid transfer protein allergens: no cross-reactivity between those from foods and olive and Parietaria pollen.
Int Arch Allergy Immunol 2011; 156(3):291-6IA

Abstract

BACKGROUND

Cross-reactivity among plant food allergens belonging to the nonspecific lipid transfer protein (LTP) family is well known. In contrast, the relationship among these allergens and their putative homologs from olive (Ole e 7) and Parietaria (Par j 1) pollen has not been clarified.

METHODS

Sera with specific IgE to LTP allergens were obtained from peach-, mustard- and olive pollen-allergic patients. Purified LTP allergens from foods (peach, apple, mustard and wheat) and pollens (olive, mugwort and Parietaria) were tested by ELISA and ELISA-inhibition assays.

RESULTS

Plant food LTP-allergic patients showed a significantly higher number of sera (89-100 vs. 33-64%) with specific IgE and mean specific IgE levels (0.30-1.56 vs. 0.21-0.34 OD units) to the 4 food LTP allergens tested than to olive Ole e 7 and Parietaria Par j 1 pollen. ELISA-inhibition assays indicated cross-inhibition between food LTP allergens but no cross-reactivity between these allergens and Ole e 7 and Par j 1, or, even more, between the LTP allergens from olive and Parietaria pollen.

CONCLUSIONS

LTP allergens from olive and Parietaria pollen cross-react neither with allergenic LTPs from plant foods nor between themselves. Therefore, both pollens do not seem to be related with the LTP syndrome.

Authors+Show Affiliations

Unidad de Bioquímica, Departamento de Biotecnología, E.T.S. Ingenieros Agrónomos, UPM, Madrid, España.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21720174

Citation

Tordesillas, Leticia, et al. "Plant Lipid Transfer Protein Allergens: No Cross-reactivity Between Those From Foods and Olive and Parietaria Pollen." International Archives of Allergy and Immunology, vol. 156, no. 3, 2011, pp. 291-6.
Tordesillas L, Sirvent S, Díaz-Perales A, et al. Plant lipid transfer protein allergens: no cross-reactivity between those from foods and olive and Parietaria pollen. Int Arch Allergy Immunol. 2011;156(3):291-6.
Tordesillas, L., Sirvent, S., Díaz-Perales, A., Villalba, M., Cuesta-Herranz, J., Rodríguez, R., & Salcedo, G. (2011). Plant lipid transfer protein allergens: no cross-reactivity between those from foods and olive and Parietaria pollen. International Archives of Allergy and Immunology, 156(3), pp. 291-6. doi:10.1159/000323503.
Tordesillas L, et al. Plant Lipid Transfer Protein Allergens: No Cross-reactivity Between Those From Foods and Olive and Parietaria Pollen. Int Arch Allergy Immunol. 2011;156(3):291-6. PubMed PMID: 21720174.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Plant lipid transfer protein allergens: no cross-reactivity between those from foods and olive and Parietaria pollen. AU - Tordesillas,Leticia, AU - Sirvent,Sofía, AU - Díaz-Perales,Araceli, AU - Villalba,Mayte, AU - Cuesta-Herranz,Javier, AU - Rodríguez,Rosalía, AU - Salcedo,Gabriel, Y1 - 2011/06/29/ PY - 2010/08/10/received PY - 2010/12/06/accepted PY - 2011/7/2/entrez PY - 2011/7/2/pubmed PY - 2011/12/13/medline SP - 291 EP - 6 JF - International archives of allergy and immunology JO - Int. Arch. Allergy Immunol. VL - 156 IS - 3 N2 - BACKGROUND: Cross-reactivity among plant food allergens belonging to the nonspecific lipid transfer protein (LTP) family is well known. In contrast, the relationship among these allergens and their putative homologs from olive (Ole e 7) and Parietaria (Par j 1) pollen has not been clarified. METHODS: Sera with specific IgE to LTP allergens were obtained from peach-, mustard- and olive pollen-allergic patients. Purified LTP allergens from foods (peach, apple, mustard and wheat) and pollens (olive, mugwort and Parietaria) were tested by ELISA and ELISA-inhibition assays. RESULTS: Plant food LTP-allergic patients showed a significantly higher number of sera (89-100 vs. 33-64%) with specific IgE and mean specific IgE levels (0.30-1.56 vs. 0.21-0.34 OD units) to the 4 food LTP allergens tested than to olive Ole e 7 and Parietaria Par j 1 pollen. ELISA-inhibition assays indicated cross-inhibition between food LTP allergens but no cross-reactivity between these allergens and Ole e 7 and Par j 1, or, even more, between the LTP allergens from olive and Parietaria pollen. CONCLUSIONS: LTP allergens from olive and Parietaria pollen cross-react neither with allergenic LTPs from plant foods nor between themselves. Therefore, both pollens do not seem to be related with the LTP syndrome. SN - 1423-0097 UR - https://www.unboundmedicine.com/medline/citation/21720174/Plant_lipid_transfer_protein_allergens:_no_cross_reactivity_between_those_from_foods_and_olive_and_Parietaria_pollen_ L2 - https://www.karger.com?DOI=10.1159/000323503 DB - PRIME DP - Unbound Medicine ER -