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Oral ulcers and necrotizing gingivitis in relation to HIV-associated neutropenia: a review and an illustrative case.
AIDS Res Hum Retroviruses. 2012 Apr; 28(4):346-51.AR

Abstract

An unusual case of necrotizing gingivitis and neutropenic oral ulcers in an HIV-seropositive patient is presented. In spite of a very low CD4(+) T cell count and severe neutropenia, the necrotizing gingivitis responded favorably to standard periodontal treatment, and the oral ulcers healed after administration of granulocyte colony-stimulating factor (G-CSF). Nonspecific oral ulcers in HIV-seropositive subjects with neutropenia should be regarded as neutropenic ulcers. The term nonspecific ulcers should be restricted to those ulcers with nonspecific histopathological features in patients without neutropenia or a nutritional deficiency such as iron, folic acid, and vitamin B.

Authors+Show Affiliations

Department of Periodontology and Oral Medicine, University of Limpopo, Pretoria, South Africa. lfeller@ul.ac.zaNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

21728927

Citation

Feller, Liviu, et al. "Oral Ulcers and Necrotizing Gingivitis in Relation to HIV-associated Neutropenia: a Review and an Illustrative Case." AIDS Research and Human Retroviruses, vol. 28, no. 4, 2012, pp. 346-51.
Feller L, Khammissa RA, Wood NH, et al. Oral ulcers and necrotizing gingivitis in relation to HIV-associated neutropenia: a review and an illustrative case. AIDS Res Hum Retroviruses. 2012;28(4):346-51.
Feller, L., Khammissa, R. A., Wood, N. H., Meyerov, R., Pantanowitz, L., & Lemmer, J. (2012). Oral ulcers and necrotizing gingivitis in relation to HIV-associated neutropenia: a review and an illustrative case. AIDS Research and Human Retroviruses, 28(4), 346-51. https://doi.org/10.1089/AID.2011.0141
Feller L, et al. Oral Ulcers and Necrotizing Gingivitis in Relation to HIV-associated Neutropenia: a Review and an Illustrative Case. AIDS Res Hum Retroviruses. 2012;28(4):346-51. PubMed PMID: 21728927.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Oral ulcers and necrotizing gingivitis in relation to HIV-associated neutropenia: a review and an illustrative case. AU - Feller,Liviu, AU - Khammissa,Razia A G, AU - Wood,Neil H, AU - Meyerov,Robin, AU - Pantanowitz,Liron, AU - Lemmer,Johan, Y1 - 2011/08/05/ PY - 2011/7/7/entrez PY - 2011/7/7/pubmed PY - 2012/7/17/medline SP - 346 EP - 51 JF - AIDS research and human retroviruses JO - AIDS Res Hum Retroviruses VL - 28 IS - 4 N2 - An unusual case of necrotizing gingivitis and neutropenic oral ulcers in an HIV-seropositive patient is presented. In spite of a very low CD4(+) T cell count and severe neutropenia, the necrotizing gingivitis responded favorably to standard periodontal treatment, and the oral ulcers healed after administration of granulocyte colony-stimulating factor (G-CSF). Nonspecific oral ulcers in HIV-seropositive subjects with neutropenia should be regarded as neutropenic ulcers. The term nonspecific ulcers should be restricted to those ulcers with nonspecific histopathological features in patients without neutropenia or a nutritional deficiency such as iron, folic acid, and vitamin B. SN - 1931-8405 UR - https://www.unboundmedicine.com/medline/citation/21728927/Oral_ulcers_and_necrotizing_gingivitis_in_relation_to_HIV_associated_neutropenia:_a_review_and_an_illustrative_case_ L2 - https://www.liebertpub.com/doi/10.1089/AID.2011.0141?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -