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Alertness can be improved by an interaction between orienting attention and alerting attention in schizophrenia.
Behav Brain Funct 2011; 7:24BB

Abstract

BACKGROUND

Attention is impaired in schizophrenia. Early attention components include orienting and alerting, as well as executive control networks. Previous studies have shown mainly executive control deficits, while few of them found orienting and alerting abnormalities. Here we explore the different attentive networks, their modulation and interactions in patients with schizophrenia.

METHODS

Twenty-one schizophrenic patients (DSMIV), compared to 21 controls, performed a modified version of the Attention Network Task, in which an orienting paradigm (with valid, invalid and no cues) was combined with a flanker task (congruent/incongruent) and an alerting signal (tone/no tone), to assess orienting, executive control and alerting networks independently.

RESULTS

Patients showed an abnormal alerting effect and slower overall reaction time compared to controls. Moreover, there was an interaction between orienting and alerting: patients are helped more than controls by the alerting signal in a valid orientation to solve the incongruent condition.

CONCLUSION

These results suggest that patients with schizophrenia have altered alerting abilities. However, the orienting and alerting cues interact to improve their attention performance in the resolution of conflict, creating possibilities for cognitive remediation strategies.

Authors+Show Affiliations

INSERM, Physiopathologie des Maladies Psychiatriques, U894-7; Centre de Psychiatrie et Neurosciences Paris, France. i.amado@ch-sainte-anne.frNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21729299

Citation

Amado, Isabelle, et al. "Alertness Can Be Improved By an Interaction Between Orienting Attention and Alerting Attention in Schizophrenia." Behavioral and Brain Functions : BBF, vol. 7, 2011, p. 24.
Amado I, Lupiañez J, Chirio M, et al. Alertness can be improved by an interaction between orienting attention and alerting attention in schizophrenia. Behav Brain Funct. 2011;7:24.
Amado, I., Lupiañez, J., Chirio, M., Landgraf, S., Willard, D., Olié, J. P., & Krebs, M. O. (2011). Alertness can be improved by an interaction between orienting attention and alerting attention in schizophrenia. Behavioral and Brain Functions : BBF, 7, p. 24. doi:10.1186/1744-9081-7-24.
Amado I, et al. Alertness Can Be Improved By an Interaction Between Orienting Attention and Alerting Attention in Schizophrenia. Behav Brain Funct. 2011 Jul 5;7:24. PubMed PMID: 21729299.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Alertness can be improved by an interaction between orienting attention and alerting attention in schizophrenia. AU - Amado,Isabelle, AU - Lupiañez,Juan, AU - Chirio,Marion, AU - Landgraf,Steffen, AU - Willard,Dominique, AU - Olié,J P Jean-Pierre, AU - Krebs,Marie Odile, Y1 - 2011/07/05/ PY - 2010/11/21/received PY - 2011/07/05/accepted PY - 2011/7/7/entrez PY - 2011/7/7/pubmed PY - 2012/5/26/medline SP - 24 EP - 24 JF - Behavioral and brain functions : BBF JO - Behav Brain Funct VL - 7 N2 - BACKGROUND: Attention is impaired in schizophrenia. Early attention components include orienting and alerting, as well as executive control networks. Previous studies have shown mainly executive control deficits, while few of them found orienting and alerting abnormalities. Here we explore the different attentive networks, their modulation and interactions in patients with schizophrenia. METHODS: Twenty-one schizophrenic patients (DSMIV), compared to 21 controls, performed a modified version of the Attention Network Task, in which an orienting paradigm (with valid, invalid and no cues) was combined with a flanker task (congruent/incongruent) and an alerting signal (tone/no tone), to assess orienting, executive control and alerting networks independently. RESULTS: Patients showed an abnormal alerting effect and slower overall reaction time compared to controls. Moreover, there was an interaction between orienting and alerting: patients are helped more than controls by the alerting signal in a valid orientation to solve the incongruent condition. CONCLUSION: These results suggest that patients with schizophrenia have altered alerting abilities. However, the orienting and alerting cues interact to improve their attention performance in the resolution of conflict, creating possibilities for cognitive remediation strategies. SN - 1744-9081 UR - https://www.unboundmedicine.com/medline/citation/21729299/Alertness_can_be_improved_by_an_interaction_between_orienting_attention_and_alerting_attention_in_schizophrenia_ L2 - https://behavioralandbrainfunctions.biomedcentral.com/articles/10.1186/1744-9081-7-24 DB - PRIME DP - Unbound Medicine ER -