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The confusion about dietary fatty acids recommendations for CHD prevention.
Br J Nutr 2011; 106(5):627-32BJ

Abstract

A recent meta-analysis of prospective cohort studies has not found an association between dietary saturated fat intake and CHD incidence. This funnelled the discussion about the importance of the recommendation to lower the intake of saturated fat for the prevention of CHD. At the same time a document of the European Food Safety Authority has suggested that specific quantitative recommendations are not needed for individual fatty acids but that more general statements can suffice. In this review, we discuss methodological aspects of the absence of association between SFA intake and CHD incidence in prospective cohort studies. We also summarise the results of the controlled dietary experiments on blood lipids and on CHD incidence in which saturated fat was replaced by either cis-unsaturated fat or carbohydrates. Finally, we propose a nutritionally adequate diet with an optimal fatty acid composition for the prevention of CHD in the context of dietary patterns. Such diets are characterised by a low intake of saturated fat, and as low as possible intake of trans-fat and fulfil the requirements for the intake of n-6 and n-3 fatty acids. No recommendation is needed for the intake of cis-MUFA.

Authors+Show Affiliations

Division of Human Nutrition, Wageningen University, PO Box 8129, 6700 EV Wageningen, the Netherlands. daan.kromhout@wur.nlNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21733329

Citation

Kromhout, Daan, et al. "The Confusion About Dietary Fatty Acids Recommendations for CHD Prevention." The British Journal of Nutrition, vol. 106, no. 5, 2011, pp. 627-32.
Kromhout D, Geleijnse JM, Menotti A, et al. The confusion about dietary fatty acids recommendations for CHD prevention. Br J Nutr. 2011;106(5):627-32.
Kromhout, D., Geleijnse, J. M., Menotti, A., & Jacobs, D. R. (2011). The confusion about dietary fatty acids recommendations for CHD prevention. The British Journal of Nutrition, 106(5), pp. 627-32. doi:10.1017/S0007114511002236.
Kromhout D, et al. The Confusion About Dietary Fatty Acids Recommendations for CHD Prevention. Br J Nutr. 2011;106(5):627-32. PubMed PMID: 21733329.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The confusion about dietary fatty acids recommendations for CHD prevention. AU - Kromhout,Daan, AU - Geleijnse,Johanna M, AU - Menotti,Alessandro, AU - Jacobs,David R,Jr Y1 - 2011/06/27/ PY - 2011/7/8/entrez PY - 2011/7/8/pubmed PY - 2011/10/14/medline SP - 627 EP - 32 JF - The British journal of nutrition JO - Br. J. Nutr. VL - 106 IS - 5 N2 - A recent meta-analysis of prospective cohort studies has not found an association between dietary saturated fat intake and CHD incidence. This funnelled the discussion about the importance of the recommendation to lower the intake of saturated fat for the prevention of CHD. At the same time a document of the European Food Safety Authority has suggested that specific quantitative recommendations are not needed for individual fatty acids but that more general statements can suffice. In this review, we discuss methodological aspects of the absence of association between SFA intake and CHD incidence in prospective cohort studies. We also summarise the results of the controlled dietary experiments on blood lipids and on CHD incidence in which saturated fat was replaced by either cis-unsaturated fat or carbohydrates. Finally, we propose a nutritionally adequate diet with an optimal fatty acid composition for the prevention of CHD in the context of dietary patterns. Such diets are characterised by a low intake of saturated fat, and as low as possible intake of trans-fat and fulfil the requirements for the intake of n-6 and n-3 fatty acids. No recommendation is needed for the intake of cis-MUFA. SN - 1475-2662 UR - https://www.unboundmedicine.com/medline/citation/21733329/The_confusion_about_dietary_fatty_acids_recommendations_for_CHD_prevention_ L2 - https://www.cambridge.org/core/product/identifier/S0007114511002236/type/journal_article DB - PRIME DP - Unbound Medicine ER -