Tags

Type your tag names separated by a space and hit enter

[Preliminary study on genotypic diversity of Streptococcus mutans in Xinjiang Uygur preschool children].
Zhonghua Kou Qiang Yi Xue Za Zhi. 2011 May; 46(5):267-71.ZK

Abstract

OBJECTIVE

To investigate the relationship between genotypic diversity of Streptococcus mutans (Sm) and deciduous teeth caries in Xinjiang Uygur autonomous region.

METHODS

Isolates of Sm were obtained from 17 caries-free and 17 caries-active Uygur preschool children aged from 3 to 5 years. A total of 143 isolates were subcultured, biochemically characterised and identified by polymerase chain reaction (PCR) as Sm and Streptococcus sobrinus (Ss). Then the Sm isolates were genotyped by arbitrarily primed-PCR (AP-PCR).

RESULTS

A total of 81 Sm isolates from caries-active subjects and 62 isolates from caries-free subjects were identified by PCR and forty distinct genotypes identified from 143 clinical isolates. In seventeen caries-active group, 9 children had only 1 genotype, 5 children had 2 genotypes, 3 children had 3 genotypes. In seventeen caries-free group, 14 children had only 1 genotype, 3 children had more than 2 genotypes. The Spearman correlation test showed a strong association between genotypic diversity and caries experience (r = 0.342, P < 0.05).

CONCLUSIONS

Isolates of Sm in caries-active Uygur preschool children show apparent more genetic diversity than those in caries-free children. The genotypes of isolates might be related to differences in caries susceptibility.

Authors+Show Affiliations

Department of Cariology Endodontology and Operative Dentistry, Xinjiang Medical University, Urümqi 830054, China.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

chi

PubMed ID

21733377

Citation

Lin, Jing, et al. "[Preliminary Study On Genotypic Diversity of Streptococcus Mutans in Xinjiang Uygur Preschool Children]." Zhonghua Kou Qiang Yi Xue Za Zhi = Zhonghua Kouqiang Yixue Zazhi = Chinese Journal of Stomatology, vol. 46, no. 5, 2011, pp. 267-71.
Lin J, Zhao J, Nurbiye M, et al. [Preliminary study on genotypic diversity of Streptococcus mutans in Xinjiang Uygur preschool children]. Zhonghua Kou Qiang Yi Xue Za Zhi. 2011;46(5):267-71.
Lin, J., Zhao, J., Nurbiye, M., & Li, X. S. (2011). [Preliminary study on genotypic diversity of Streptococcus mutans in Xinjiang Uygur preschool children]. Zhonghua Kou Qiang Yi Xue Za Zhi = Zhonghua Kouqiang Yixue Zazhi = Chinese Journal of Stomatology, 46(5), 267-71.
Lin J, et al. [Preliminary Study On Genotypic Diversity of Streptococcus Mutans in Xinjiang Uygur Preschool Children]. Zhonghua Kou Qiang Yi Xue Za Zhi. 2011;46(5):267-71. PubMed PMID: 21733377.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Preliminary study on genotypic diversity of Streptococcus mutans in Xinjiang Uygur preschool children]. AU - Lin,Jing, AU - Zhao,Jin, AU - Nurbiye,Munammetemin, AU - Li,Xin-shang, PY - 2011/7/8/entrez PY - 2011/7/8/pubmed PY - 2014/9/23/medline SP - 267 EP - 71 JF - Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology JO - Zhonghua Kou Qiang Yi Xue Za Zhi VL - 46 IS - 5 N2 - OBJECTIVE: To investigate the relationship between genotypic diversity of Streptococcus mutans (Sm) and deciduous teeth caries in Xinjiang Uygur autonomous region. METHODS: Isolates of Sm were obtained from 17 caries-free and 17 caries-active Uygur preschool children aged from 3 to 5 years. A total of 143 isolates were subcultured, biochemically characterised and identified by polymerase chain reaction (PCR) as Sm and Streptococcus sobrinus (Ss). Then the Sm isolates were genotyped by arbitrarily primed-PCR (AP-PCR). RESULTS: A total of 81 Sm isolates from caries-active subjects and 62 isolates from caries-free subjects were identified by PCR and forty distinct genotypes identified from 143 clinical isolates. In seventeen caries-active group, 9 children had only 1 genotype, 5 children had 2 genotypes, 3 children had 3 genotypes. In seventeen caries-free group, 14 children had only 1 genotype, 3 children had more than 2 genotypes. The Spearman correlation test showed a strong association between genotypic diversity and caries experience (r = 0.342, P < 0.05). CONCLUSIONS: Isolates of Sm in caries-active Uygur preschool children show apparent more genetic diversity than those in caries-free children. The genotypes of isolates might be related to differences in caries susceptibility. SN - 1002-0098 UR - https://www.unboundmedicine.com/medline/citation/21733377/[Preliminary_study_on_genotypic_diversity_of_Streptococcus_mutans_in_Xinjiang_Uygur_preschool_children]_ L2 - http://journal.yiigle.com/LinkIn.do?linkin_type=pubmed&amp;issn=1002-0098&amp;year=2011&amp;vol=46&amp;issue=5&amp;fpage=267 DB - PRIME DP - Unbound Medicine ER -