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Differential relationship between metabolic syndrome score and severity of coronary atherosclerosis as assessed by angiography in a non-diabetic and diabetic Korean population.
J Korean Med Sci. 2011 Jul; 26(7):900-5.JK

Abstract

Whether the metabolic syndrome (MetS) has prognostic value for coronary artery disease (CAD) beyond its individual components is controversial. We compared the relationship between the number of MetS components and CAD severity as assessed by angiography in non-diabetic and diabetic subjects. We consecutively enrolled 527 patients who underwent their first coronary angiography. Patients were divided into four groups according to the number of MetS components: 0/1, 2, 3, and 4/5. A coronary atherosclerosis score was used to quantify the extent of atherosclerotic involvement. The relationship between the MetS score and angiographic CAD severity or clinical presentation was compared between non-diabetic and diabetic subjects. Individuals with the MetS (n = 327) had a higher prevalence of CAD (60% vs 32%, P < 0.001), multi-vessel disease (34% vs 16%, P < 0.001), and acute coronary syndromes (49% vs 26%, P < 0.001) than those without the MetS. In the non-diabetic group, atherosclerosis score increased with the MetS score (1.0 ± 2.1, 2.0 ± 2.9, 2.8 ± 2.9, and 3.6 ± 3.9, P < 0.001) whereas there was no significant difference in the diabetic group (0.5 ± 1.0, 5.2 ± 4.7, 4.2 ± 2.9, and 4.4 ± 3.5, P = 0.102). The MetS score is related to CAD severity in non-diabetic patients but the association between the MetS score and angiographic CAD severity may be obscured in the presence of diabetes.

Authors+Show Affiliations

Department of Medicine, Sunlin Hospital, Pohang, Korea.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21738343

Citation

Yoon, Shin-Eui, et al. "Differential Relationship Between Metabolic Syndrome Score and Severity of Coronary Atherosclerosis as Assessed By Angiography in a Non-diabetic and Diabetic Korean Population." Journal of Korean Medical Science, vol. 26, no. 7, 2011, pp. 900-5.
Yoon SE, Ahn SG, Kim JY, et al. Differential relationship between metabolic syndrome score and severity of coronary atherosclerosis as assessed by angiography in a non-diabetic and diabetic Korean population. J Korean Med Sci. 2011;26(7):900-5.
Yoon, S. E., Ahn, S. G., Kim, J. Y., Park, J. S., Shin, J. H., Tahk, S. J., Lee, S. K., Kim, T. J., & Han, N. (2011). Differential relationship between metabolic syndrome score and severity of coronary atherosclerosis as assessed by angiography in a non-diabetic and diabetic Korean population. Journal of Korean Medical Science, 26(7), 900-5. https://doi.org/10.3346/jkms.2011.26.7.900
Yoon SE, et al. Differential Relationship Between Metabolic Syndrome Score and Severity of Coronary Atherosclerosis as Assessed By Angiography in a Non-diabetic and Diabetic Korean Population. J Korean Med Sci. 2011;26(7):900-5. PubMed PMID: 21738343.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Differential relationship between metabolic syndrome score and severity of coronary atherosclerosis as assessed by angiography in a non-diabetic and diabetic Korean population. AU - Yoon,Shin-Eui, AU - Ahn,Sung Gyun, AU - Kim,Jang-Young, AU - Park,Jin-Sun, AU - Shin,Joon-Han, AU - Tahk,Seung-Jea, AU - Lee,Su-Kyeong, AU - Kim,Tae-Jin, AU - Han,Na, Y1 - 2011/06/20/ PY - 2011/03/02/received PY - 2011/04/21/accepted PY - 2011/7/9/entrez PY - 2011/7/9/pubmed PY - 2011/10/28/medline KW - Coronary Angiography KW - Coronary Atherosclerosis KW - Metabolic Syndrome SP - 900 EP - 5 JF - Journal of Korean medical science JO - J Korean Med Sci VL - 26 IS - 7 N2 - Whether the metabolic syndrome (MetS) has prognostic value for coronary artery disease (CAD) beyond its individual components is controversial. We compared the relationship between the number of MetS components and CAD severity as assessed by angiography in non-diabetic and diabetic subjects. We consecutively enrolled 527 patients who underwent their first coronary angiography. Patients were divided into four groups according to the number of MetS components: 0/1, 2, 3, and 4/5. A coronary atherosclerosis score was used to quantify the extent of atherosclerotic involvement. The relationship between the MetS score and angiographic CAD severity or clinical presentation was compared between non-diabetic and diabetic subjects. Individuals with the MetS (n = 327) had a higher prevalence of CAD (60% vs 32%, P < 0.001), multi-vessel disease (34% vs 16%, P < 0.001), and acute coronary syndromes (49% vs 26%, P < 0.001) than those without the MetS. In the non-diabetic group, atherosclerosis score increased with the MetS score (1.0 ± 2.1, 2.0 ± 2.9, 2.8 ± 2.9, and 3.6 ± 3.9, P < 0.001) whereas there was no significant difference in the diabetic group (0.5 ± 1.0, 5.2 ± 4.7, 4.2 ± 2.9, and 4.4 ± 3.5, P = 0.102). The MetS score is related to CAD severity in non-diabetic patients but the association between the MetS score and angiographic CAD severity may be obscured in the presence of diabetes. SN - 1598-6357 UR - https://www.unboundmedicine.com/medline/citation/21738343/Differential_relationship_between_metabolic_syndrome_score_and_severity_of_coronary_atherosclerosis_as_assessed_by_angiography_in_a_non_diabetic_and_diabetic_Korean_population_ L2 - https://jkms.org/DOIx.php?id=10.3346/jkms.2011.26.7.900 DB - PRIME DP - Unbound Medicine ER -