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Management of recurrent pterygium with intraoperative mitomycin C and conjunctival autograft with fibrin glue.
Am J Ophthalmol. 2011 Nov; 152(5):730-2.AJ

Abstract

PURPOSE

To evaluate the safety and efficacy of using fibrin glue in cases of recurrent pterygium treated with pterygium excision and conjunctival autograft combined with mitomycin C.

DESIGN

Retrospective, interventional case series.

METHODS

The charts of 28 patients with recurrent pterygium who had undergone pterygium excision and conjunctival autograft using fibrin glue to secure the graft combined with intraoperative mitomycin C at a corneal service in a university teaching hospital were reviewed. Inclusion criteria were recurrent pterygium that had undergone at least 1 previous surgical excision and patients who had completed a regular postoperative follow-up of at least 12 months. Outcome measures included mean best-corrected visual acuity (BCVA) and intraoperative and postoperative complications.

RESULTS

The mean age of the cohort was 49.7 years. There were no intraoperative complications. Early postoperative total graft dehiscence developed in 1 eye that underwent repositioning with glue and sutures. One eye had mild graft dehiscence and required no surgical intervention. One eye had a conjunctival cyst on the graft that did not require intervention. No significant change was observed in BCVA. At a mean follow-up of 26.5 months, there was 1 case of recurrence.

CONCLUSIONS

Pterygium excision and conjunctival autograft using fibrin glue to secure the graft combined with intraoperative mitomycin C seems to be a safe and effective surgical option for treating recurrent pterygium. However, a larger cohort with longer follow-up may be required to assess the recurrence rate of this method.

Authors+Show Affiliations

Department of Ophthalmology, Toronto Western Hospital, University of Toronto, Toronto, Canada. raneen_sh_mash@hotmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21742307

Citation

Shehadeh-Mashor, Raneen, et al. "Management of Recurrent Pterygium With Intraoperative Mitomycin C and Conjunctival Autograft With Fibrin Glue." American Journal of Ophthalmology, vol. 152, no. 5, 2011, pp. 730-2.
Shehadeh-Mashor R, Srinivasan S, Boimer C, et al. Management of recurrent pterygium with intraoperative mitomycin C and conjunctival autograft with fibrin glue. Am J Ophthalmol. 2011;152(5):730-2.
Shehadeh-Mashor, R., Srinivasan, S., Boimer, C., Lee, K., Tomkins, O., & Slomovic, A. R. (2011). Management of recurrent pterygium with intraoperative mitomycin C and conjunctival autograft with fibrin glue. American Journal of Ophthalmology, 152(5), 730-2. https://doi.org/10.1016/j.ajo.2011.04.034
Shehadeh-Mashor R, et al. Management of Recurrent Pterygium With Intraoperative Mitomycin C and Conjunctival Autograft With Fibrin Glue. Am J Ophthalmol. 2011;152(5):730-2. PubMed PMID: 21742307.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Management of recurrent pterygium with intraoperative mitomycin C and conjunctival autograft with fibrin glue. AU - Shehadeh-Mashor,Raneen, AU - Srinivasan,Sathish, AU - Boimer,Corey, AU - Lee,Kenneth, AU - Tomkins,Oren, AU - Slomovic,Allan R, Y1 - 2011/07/13/ PY - 2011/02/03/received PY - 2011/04/27/revised PY - 2011/04/29/accepted PY - 2011/7/12/entrez PY - 2011/7/12/pubmed PY - 2011/12/15/medline SP - 730 EP - 2 JF - American journal of ophthalmology JO - Am J Ophthalmol VL - 152 IS - 5 N2 - PURPOSE: To evaluate the safety and efficacy of using fibrin glue in cases of recurrent pterygium treated with pterygium excision and conjunctival autograft combined with mitomycin C. DESIGN: Retrospective, interventional case series. METHODS: The charts of 28 patients with recurrent pterygium who had undergone pterygium excision and conjunctival autograft using fibrin glue to secure the graft combined with intraoperative mitomycin C at a corneal service in a university teaching hospital were reviewed. Inclusion criteria were recurrent pterygium that had undergone at least 1 previous surgical excision and patients who had completed a regular postoperative follow-up of at least 12 months. Outcome measures included mean best-corrected visual acuity (BCVA) and intraoperative and postoperative complications. RESULTS: The mean age of the cohort was 49.7 years. There were no intraoperative complications. Early postoperative total graft dehiscence developed in 1 eye that underwent repositioning with glue and sutures. One eye had mild graft dehiscence and required no surgical intervention. One eye had a conjunctival cyst on the graft that did not require intervention. No significant change was observed in BCVA. At a mean follow-up of 26.5 months, there was 1 case of recurrence. CONCLUSIONS: Pterygium excision and conjunctival autograft using fibrin glue to secure the graft combined with intraoperative mitomycin C seems to be a safe and effective surgical option for treating recurrent pterygium. However, a larger cohort with longer follow-up may be required to assess the recurrence rate of this method. SN - 1879-1891 UR - https://www.unboundmedicine.com/medline/citation/21742307/Management_of_recurrent_pterygium_with_intraoperative_mitomycin_C_and_conjunctival_autograft_with_fibrin_glue_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0002-9394(11)00374-6 DB - PRIME DP - Unbound Medicine ER -