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Isoiridomyrmecin rich essential oil from Nepeta erecta Benth. and its antioxidant activity.
Nat Prod Res. 2012; 26(1):29-35.NP

Abstract

The essential oil composition of the aerial parts of Nepeta erecta Benth. (Family: Lamiaceae) from Uttarakhand, India was analysed by capillary gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). A total of 34 constituents were identified representing 94.6% of the oil composition. Oxygenated monoterpenes (74.0%) constituted the major proportion of the oil, dominated by isoiridomyrmecin (70.6%) as a single major constituent. Other significant constituents were caryophyllene oxide (9.6%), β-Bourbonene (2.0%), humulene epoxide II (1.7%) and linalool (1.0%). The in vitro antioxidant activity (AOA) was assessed using β-Carotene bleaching assay, reducing power, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging and inhibition of lipid peroxidation methods. The oil was found to exhibit AOA by inhibiting β-Carotene bleaching (54.6 ± 2.52%) and by scavenging DPPH free radical (IC(50) = 0.74 ± 0.12 mg mL(-1)). The AOA of the essential oil of N. erecta and its major compound isoiridomyrmecin has not been reported so far.

Authors+Show Affiliations

Department of Chemistry, Kumaun University, Uttarakhand, India.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21756190

Citation

Bisht, Dinesh S., et al. "Isoiridomyrmecin Rich Essential Oil From Nepeta Erecta Benth. and Its Antioxidant Activity." Natural Product Research, vol. 26, no. 1, 2012, pp. 29-35.
Bisht DS, Joshi SC, Padalia RC, et al. Isoiridomyrmecin rich essential oil from Nepeta erecta Benth. and its antioxidant activity. Nat Prod Res. 2012;26(1):29-35.
Bisht, D. S., Joshi, S. C., Padalia, R. C., & Mathela, C. S. (2012). Isoiridomyrmecin rich essential oil from Nepeta erecta Benth. and its antioxidant activity. Natural Product Research, 26(1), 29-35. https://doi.org/10.1080/14786419.2010.531393
Bisht DS, et al. Isoiridomyrmecin Rich Essential Oil From Nepeta Erecta Benth. and Its Antioxidant Activity. Nat Prod Res. 2012;26(1):29-35. PubMed PMID: 21756190.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Isoiridomyrmecin rich essential oil from Nepeta erecta Benth. and its antioxidant activity. AU - Bisht,Dinesh S, AU - Joshi,Subhash C, AU - Padalia,Rajendra C, AU - Mathela,Chandra S, Y1 - 2011/07/15/ PY - 2011/7/16/entrez PY - 2011/7/16/pubmed PY - 2012/4/10/medline SP - 29 EP - 35 JF - Natural product research JO - Nat Prod Res VL - 26 IS - 1 N2 - The essential oil composition of the aerial parts of Nepeta erecta Benth. (Family: Lamiaceae) from Uttarakhand, India was analysed by capillary gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). A total of 34 constituents were identified representing 94.6% of the oil composition. Oxygenated monoterpenes (74.0%) constituted the major proportion of the oil, dominated by isoiridomyrmecin (70.6%) as a single major constituent. Other significant constituents were caryophyllene oxide (9.6%), β-Bourbonene (2.0%), humulene epoxide II (1.7%) and linalool (1.0%). The in vitro antioxidant activity (AOA) was assessed using β-Carotene bleaching assay, reducing power, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging and inhibition of lipid peroxidation methods. The oil was found to exhibit AOA by inhibiting β-Carotene bleaching (54.6 ± 2.52%) and by scavenging DPPH free radical (IC(50) = 0.74 ± 0.12 mg mL(-1)). The AOA of the essential oil of N. erecta and its major compound isoiridomyrmecin has not been reported so far. SN - 1478-6427 UR - https://www.unboundmedicine.com/medline/citation/21756190/Isoiridomyrmecin_rich_essential_oil_from_Nepeta_erecta_Benth__and_its_antioxidant_activity_ DB - PRIME DP - Unbound Medicine ER -