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Coal dust exposure and mortality from ischemic heart disease among a cohort of U.S. coal miners.
Am J Ind Med 2011; 54(10):727-33AJ

Abstract

BACKGROUND

Particulate exposure from air pollution increases the risk of ischemic heart disease (IHD) mortality. Although coal miners are highly exposed to coal dust particulate, studies of IHD mortality risk among coal miners have had inconsistent results. Previous studies may have been biased by the healthy worker effect.

METHODS

We examined the dose-response relationship between cumulative coal dust exposure, coal rank, and IHD mortality among a cohort of underground coal miners who participated in the National Study of Coal Workers' Pneumoconiosis.

RESULTS

After adjusting for age, smoking, and body mass index, risk of IHD mortality increased at higher levels of coal dust exposure. Mortality risk was also associated with coal rank region.

CONCLUSION

There was an increased risk of mortality from IHD associated with cumulative exposure to coal dust, and with coal rank. The effect of coal rank may be due differences in the composition of coal mine dust particulate. The association of risk of IHD mortality with cumulative particulate exposure is consistent with air pollution studies.

Authors+Show Affiliations

Office of Mine Safety and Health Research, National Institute for Occupational Safety and Health, Pittsburgh, Pennsylvania, USA. dlanden@cdc.govNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21761428

Citation

Landen, Deborah D., et al. "Coal Dust Exposure and Mortality From Ischemic Heart Disease Among a Cohort of U.S. Coal Miners." American Journal of Industrial Medicine, vol. 54, no. 10, 2011, pp. 727-33.
Landen DD, Wassell JT, McWilliams L, et al. Coal dust exposure and mortality from ischemic heart disease among a cohort of U.S. coal miners. Am J Ind Med. 2011;54(10):727-33.
Landen, D. D., Wassell, J. T., McWilliams, L., & Patel, A. (2011). Coal dust exposure and mortality from ischemic heart disease among a cohort of U.S. coal miners. American Journal of Industrial Medicine, 54(10), pp. 727-33. doi:10.1002/ajim.20986.
Landen DD, et al. Coal Dust Exposure and Mortality From Ischemic Heart Disease Among a Cohort of U.S. Coal Miners. Am J Ind Med. 2011;54(10):727-33. PubMed PMID: 21761428.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Coal dust exposure and mortality from ischemic heart disease among a cohort of U.S. coal miners. AU - Landen,Deborah D, AU - Wassell,James T, AU - McWilliams,Linda, AU - Patel,Ami, Y1 - 2011/07/14/ PY - 2011/06/11/accepted PY - 2011/7/16/entrez PY - 2011/7/16/pubmed PY - 2012/1/12/medline SP - 727 EP - 33 JF - American journal of industrial medicine JO - Am. J. Ind. Med. VL - 54 IS - 10 N2 - BACKGROUND: Particulate exposure from air pollution increases the risk of ischemic heart disease (IHD) mortality. Although coal miners are highly exposed to coal dust particulate, studies of IHD mortality risk among coal miners have had inconsistent results. Previous studies may have been biased by the healthy worker effect. METHODS: We examined the dose-response relationship between cumulative coal dust exposure, coal rank, and IHD mortality among a cohort of underground coal miners who participated in the National Study of Coal Workers' Pneumoconiosis. RESULTS: After adjusting for age, smoking, and body mass index, risk of IHD mortality increased at higher levels of coal dust exposure. Mortality risk was also associated with coal rank region. CONCLUSION: There was an increased risk of mortality from IHD associated with cumulative exposure to coal dust, and with coal rank. The effect of coal rank may be due differences in the composition of coal mine dust particulate. The association of risk of IHD mortality with cumulative particulate exposure is consistent with air pollution studies. SN - 1097-0274 UR - https://www.unboundmedicine.com/medline/citation/21761428/Coal_dust_exposure_and_mortality_from_ischemic_heart_disease_among_a_cohort_of_U_S__coal_miners_ L2 - https://doi.org/10.1002/ajim.20986 DB - PRIME DP - Unbound Medicine ER -