Tags

Type your tag names separated by a space and hit enter

An ultrasensitive hydrogen peroxide biosensor based on electrocatalytic synergy of graphene-gold nanocomposite, CdTe-CdS core-shell quantum dots and gold nanoparticles.
Anal Chim Acta. 2011 Sep 02; 701(1):75-80.AC

Abstract

We first reported an ultrasensitive hydrogen peroxide biosensor in this work. The biosensor was fabricated by coating graphene-gold nanocomposite (G-AuNP), CdTe-CdS core-shell quantum dots (CdTe-CdS), gold nanoparticles (AuNPs) and horseradish peroxidase (HRP) in sequence on the surface of gold electrode (GE). Cyclic voltammetry and differential pulse voltammetry were used to investigate electrochemical performances of the biosensor. Since promising electrocatalytic synergy of G-AuNP, CdTe-CdS and AuNPs towards hydrogen peroxide was achieved, the biosensor displayed a high sensitivity, low detection limit (S/N=3) (3.2×10(-11) M), wide calibration range (from 1×10(-10) M to 1.2×10(-8) M) and good long-term stability (20 weeks). Moreover, the effects of omitting G-AuNP, CdTe-CdS and AuNP were also examined. It was found that sensitivity of the biosensor is more 11-fold better if G-AuNP, CdTe-CdS and AuNPs are used. This could be ascribed to improvement of the conductivity between graphene nanosheets in the G-AuNP due to introduction of the AuNPs, ultrafast charge transfer from CdTe-CdS to the graphene sheets and AuNP due to unique electrochemical properties of the CdTe-CdS, and good biocompatibility of the AuNPs for horseradish peroxidase. The biosensor is of best sensitivity in all hydrogen peroxide biosensors based on graphene and its composites up to now.

Authors+Show Affiliations

School of Chemical and Material Engineering, Jiangnan University, Wuxi, PR China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Evaluation Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21763811

Citation

Gu, Zhiguo, et al. "An Ultrasensitive Hydrogen Peroxide Biosensor Based On Electrocatalytic Synergy of Graphene-gold Nanocomposite, CdTe-CdS Core-shell Quantum Dots and Gold Nanoparticles." Analytica Chimica Acta, vol. 701, no. 1, 2011, pp. 75-80.
Gu Z, Yang S, Li Z, et al. An ultrasensitive hydrogen peroxide biosensor based on electrocatalytic synergy of graphene-gold nanocomposite, CdTe-CdS core-shell quantum dots and gold nanoparticles. Anal Chim Acta. 2011;701(1):75-80.
Gu, Z., Yang, S., Li, Z., Sun, X., Wang, G., Fang, Y., & Liu, J. (2011). An ultrasensitive hydrogen peroxide biosensor based on electrocatalytic synergy of graphene-gold nanocomposite, CdTe-CdS core-shell quantum dots and gold nanoparticles. Analytica Chimica Acta, 701(1), 75-80. https://doi.org/10.1016/j.aca.2011.06.015
Gu Z, et al. An Ultrasensitive Hydrogen Peroxide Biosensor Based On Electrocatalytic Synergy of Graphene-gold Nanocomposite, CdTe-CdS Core-shell Quantum Dots and Gold Nanoparticles. Anal Chim Acta. 2011 Sep 2;701(1):75-80. PubMed PMID: 21763811.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - An ultrasensitive hydrogen peroxide biosensor based on electrocatalytic synergy of graphene-gold nanocomposite, CdTe-CdS core-shell quantum dots and gold nanoparticles. AU - Gu,Zhiguo, AU - Yang,Shuping, AU - Li,Zaijun, AU - Sun,Xiulan, AU - Wang,Guangli, AU - Fang,Yinjun, AU - Liu,Junkang, Y1 - 2011/07/04/ PY - 2011/04/21/received PY - 2011/06/08/revised PY - 2011/06/09/accepted PY - 2011/7/19/entrez PY - 2011/7/19/pubmed PY - 2011/11/2/medline SP - 75 EP - 80 JF - Analytica chimica acta JO - Anal Chim Acta VL - 701 IS - 1 N2 - We first reported an ultrasensitive hydrogen peroxide biosensor in this work. The biosensor was fabricated by coating graphene-gold nanocomposite (G-AuNP), CdTe-CdS core-shell quantum dots (CdTe-CdS), gold nanoparticles (AuNPs) and horseradish peroxidase (HRP) in sequence on the surface of gold electrode (GE). Cyclic voltammetry and differential pulse voltammetry were used to investigate electrochemical performances of the biosensor. Since promising electrocatalytic synergy of G-AuNP, CdTe-CdS and AuNPs towards hydrogen peroxide was achieved, the biosensor displayed a high sensitivity, low detection limit (S/N=3) (3.2×10(-11) M), wide calibration range (from 1×10(-10) M to 1.2×10(-8) M) and good long-term stability (20 weeks). Moreover, the effects of omitting G-AuNP, CdTe-CdS and AuNP were also examined. It was found that sensitivity of the biosensor is more 11-fold better if G-AuNP, CdTe-CdS and AuNPs are used. This could be ascribed to improvement of the conductivity between graphene nanosheets in the G-AuNP due to introduction of the AuNPs, ultrafast charge transfer from CdTe-CdS to the graphene sheets and AuNP due to unique electrochemical properties of the CdTe-CdS, and good biocompatibility of the AuNPs for horseradish peroxidase. The biosensor is of best sensitivity in all hydrogen peroxide biosensors based on graphene and its composites up to now. SN - 1873-4324 UR - https://www.unboundmedicine.com/medline/citation/21763811/An_ultrasensitive_hydrogen_peroxide_biosensor_based_on_electrocatalytic_synergy_of_graphene_gold_nanocomposite_CdTe_CdS_core_shell_quantum_dots_and_gold_nanoparticles_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0003-2670(11)00784-7 DB - PRIME DP - Unbound Medicine ER -