Tags

Type your tag names separated by a space and hit enter

Factors predictive of breast cancer in open biopsy in cases with atypical ductal hyperplasia diagnosed by ultrasound-guided core needle biopsy.
Eur J Surg Oncol. 2011 Sep; 37(9):758-64.EJ

Abstract

AIMS

The purpose of the study was to explore factors predictive of breast cancer as diagnosed by excision biopsy in cases with a diagnosis of atypical ductal hyperplasia (ADH) on ultrasound-guided core needle biopsy (CNB).

PATIENTS AND METHODS

We carried out diagnosis of breast lesions by ultrasound-guided CNB in a single hospital in Taiwan from November 2003 to October 2009. Patients who were diagnosed with ADH and subsequently underwent excision biopsy were included in this study (n = 124).

RESULTS

Fifty-six of the 124 patients who were included (45.2%) had cancer, and the remaining 68 had benign lesions. By multivariate analysis of all clinical characteristics and on the basis of the imaging features in these cases, older patient age (≥50 y/o, OR: 3.910, p = 0.005), larger tumour size (≥15 mm, OR: 3.398, p = 0.013), and the presence of architectural distortion by mammography (OR: 10.7, p = 0.036) were found likely to be associated with breast cancer.

CONCLUSIONS

Open biopsy is necessary in patients who were diagnosed with ADH on CNB. Older patients (≥50 y/o), with a larger tumour size (≥15 mm) and an abnormal mammography are especially likely to have breast cancer.

Authors+Show Affiliations

General Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, 325, Sec 2, Chen-Kung Rd, Neihu, Taipei 114, Taiwan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21764539

Citation

Hong, Z-J, et al. "Factors Predictive of Breast Cancer in Open Biopsy in Cases With Atypical Ductal Hyperplasia Diagnosed By Ultrasound-guided Core Needle Biopsy." European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, vol. 37, no. 9, 2011, pp. 758-64.
Hong ZJ, Chu CH, Fan HL, et al. Factors predictive of breast cancer in open biopsy in cases with atypical ductal hyperplasia diagnosed by ultrasound-guided core needle biopsy. Eur J Surg Oncol. 2011;37(9):758-64.
Hong, Z. J., Chu, C. H., Fan, H. L., Hsu, H. M., Chen, C. J., Chan, D. C., & Yu, J. C. (2011). Factors predictive of breast cancer in open biopsy in cases with atypical ductal hyperplasia diagnosed by ultrasound-guided core needle biopsy. European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 37(9), 758-64. https://doi.org/10.1016/j.ejso.2011.06.014
Hong ZJ, et al. Factors Predictive of Breast Cancer in Open Biopsy in Cases With Atypical Ductal Hyperplasia Diagnosed By Ultrasound-guided Core Needle Biopsy. Eur J Surg Oncol. 2011;37(9):758-64. PubMed PMID: 21764539.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Factors predictive of breast cancer in open biopsy in cases with atypical ductal hyperplasia diagnosed by ultrasound-guided core needle biopsy. AU - Hong,Z-J, AU - Chu,C-H, AU - Fan,H-L, AU - Hsu,H-M, AU - Chen,C-J, AU - Chan,D-C, AU - Yu,J-C, Y1 - 2011/07/20/ PY - 2011/03/10/received PY - 2011/06/19/revised PY - 2011/06/27/accepted PY - 2011/7/19/entrez PY - 2011/7/19/pubmed PY - 2011/10/18/medline SP - 758 EP - 64 JF - European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology JO - Eur J Surg Oncol VL - 37 IS - 9 N2 - AIMS: The purpose of the study was to explore factors predictive of breast cancer as diagnosed by excision biopsy in cases with a diagnosis of atypical ductal hyperplasia (ADH) on ultrasound-guided core needle biopsy (CNB). PATIENTS AND METHODS: We carried out diagnosis of breast lesions by ultrasound-guided CNB in a single hospital in Taiwan from November 2003 to October 2009. Patients who were diagnosed with ADH and subsequently underwent excision biopsy were included in this study (n = 124). RESULTS: Fifty-six of the 124 patients who were included (45.2%) had cancer, and the remaining 68 had benign lesions. By multivariate analysis of all clinical characteristics and on the basis of the imaging features in these cases, older patient age (≥50 y/o, OR: 3.910, p = 0.005), larger tumour size (≥15 mm, OR: 3.398, p = 0.013), and the presence of architectural distortion by mammography (OR: 10.7, p = 0.036) were found likely to be associated with breast cancer. CONCLUSIONS: Open biopsy is necessary in patients who were diagnosed with ADH on CNB. Older patients (≥50 y/o), with a larger tumour size (≥15 mm) and an abnormal mammography are especially likely to have breast cancer. SN - 1532-2157 UR - https://www.unboundmedicine.com/medline/citation/21764539/Factors_predictive_of_breast_cancer_in_open_biopsy_in_cases_with_atypical_ductal_hyperplasia_diagnosed_by_ultrasound_guided_core_needle_biopsy_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0748-7983(11)00351-9 DB - PRIME DP - Unbound Medicine ER -