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Use of allergen components begins a new era in pediatric allergology.
Pediatr Allergy Immunol 2011; 22(5):454-61PA

Abstract

Molecular allergology is a breakthrough science that enables the quantification of IgE and IgG antibodies against individual allergen protein components at a molecular level. The diagnosis of IgE-mediated allergic disorder among children is based on clinical history and sensitization demonstrated through an allergy test. Identifying whether the sensitization is primary (species specific) or a result of cross-reactivity to proteins with similar protein structures helps the clinician to judge the risk of allergic reaction. This is possible today because allergen component tests are now available for clinicians to use in everyday practice. This article focuses on clinical utility through the prediction of cross-reactivity or primary sensitization, estimation of the risk of reaction to heated food and the risk of severe clinical symptoms.

Authors+Show Affiliations

Department of Pediatrics, Sahlgrenska Academy, Göteborg University, Göteborg and Phadia AB, Uppsala, Sweden. magnus@borres.seNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

21771081

Citation

Borres, Magnus P., et al. "Use of Allergen Components Begins a New Era in Pediatric Allergology." Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology, vol. 22, no. 5, 2011, pp. 454-61.
Borres MP, Ebisawa M, Eigenmann PA. Use of allergen components begins a new era in pediatric allergology. Pediatr Allergy Immunol. 2011;22(5):454-61.
Borres, M. P., Ebisawa, M., & Eigenmann, P. A. (2011). Use of allergen components begins a new era in pediatric allergology. Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology, 22(5), pp. 454-61. doi:10.1111/j.1399-3038.2011.01197.x.
Borres MP, Ebisawa M, Eigenmann PA. Use of Allergen Components Begins a New Era in Pediatric Allergology. Pediatr Allergy Immunol. 2011;22(5):454-61. PubMed PMID: 21771081.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Use of allergen components begins a new era in pediatric allergology. AU - Borres,Magnus P, AU - Ebisawa,Motohiro, AU - Eigenmann,Philippe A, PY - 2011/7/21/entrez PY - 2011/7/21/pubmed PY - 2011/12/13/medline SP - 454 EP - 61 JF - Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology JO - Pediatr Allergy Immunol VL - 22 IS - 5 N2 - Molecular allergology is a breakthrough science that enables the quantification of IgE and IgG antibodies against individual allergen protein components at a molecular level. The diagnosis of IgE-mediated allergic disorder among children is based on clinical history and sensitization demonstrated through an allergy test. Identifying whether the sensitization is primary (species specific) or a result of cross-reactivity to proteins with similar protein structures helps the clinician to judge the risk of allergic reaction. This is possible today because allergen component tests are now available for clinicians to use in everyday practice. This article focuses on clinical utility through the prediction of cross-reactivity or primary sensitization, estimation of the risk of reaction to heated food and the risk of severe clinical symptoms. SN - 1399-3038 UR - https://www.unboundmedicine.com/medline/citation/21771081/Use_of_allergen_components_begins_a_new_era_in_pediatric_allergology_ L2 - https://doi.org/10.1111/j.1399-3038.2011.01197.x DB - PRIME DP - Unbound Medicine ER -