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Evaluation of Andrographis paniculata Burm.f. (Family:Acanthaceae) extracts against Culex quinquefasciatus (Say.) and Aedes aegypti (Linn.) (Diptera:Culicidae).
Asian Pac J Trop Med. 2011 Mar; 4(3):176-81.AP

Abstract

OBJECTIVE

To investigate the larvicidal and ovicidal efficacy of different extracts of Andrographis paniculata (A. paniculata) against Culex quinquefasciatus (Cx. quinquefasciatus) Say and Aedes aegypti (Ae. aegypti) L. (Diptera: Culicidae).

METHODS

Larvicidal efficacy of the crude leaf extracts of A. paniculata with five different solvents like benzene, hexane, ethyl acetate, methanol and chloroform was tested against the early third instar larvae of Cx. quinquefasciatus and Ae. aegypti. The ovicidal activity was determined against two mosquito species to various concentrations ranging from 50-300 ppm under the laboratory conditions.

RESULTS

The benzene, hexane, ethyl acetate, methanol and chloroform leaf extract of A. paniculata was found to be more effective against Cx. quinquefasciatus than Ae. aegypti. The LC(50) values were 112.19, 137.48, 118.67, 102.05, 91.20 ppm and 119.58, 146.34, 124.24, 110.12, 99.54 ppm respectively. Among five tested solvent, methanol and ethyl acetate crude extract was found to be most effective for ovicidal activity against two mosquito species. The extract of methanol and ethyl acetate exerted 100% mortality at 200 ppm against Cx. quinquefasciatus and at 250 ppm against Ae. aegypti.

CONCLUSIONS

From the results it can be concluded the crude extract of A. paniculata was a potential for controlling Cx. quinquefasciatus and Ae. aegypti mosquitoes.

Authors+Show Affiliations

Division of Vector Biology and Phytochemistry, Department of Zoology, Annamalai University, Annamalainagar-608 002, Tamil Nadu, India. drgovind1979@rediffmail.com

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21771448

Citation

Govindarajan, Marimuthu. "Evaluation of Andrographis Paniculata Burm.f. (Family:Acanthaceae) Extracts Against Culex Quinquefasciatus (Say.) and Aedes Aegypti (Linn.) (Diptera:Culicidae)." Asian Pacific Journal of Tropical Medicine, vol. 4, no. 3, 2011, pp. 176-81.
Govindarajan M. Evaluation of Andrographis paniculata Burm.f. (Family:Acanthaceae) extracts against Culex quinquefasciatus (Say.) and Aedes aegypti (Linn.) (Diptera:Culicidae). Asian Pac J Trop Med. 2011;4(3):176-81.
Govindarajan, M. (2011). Evaluation of Andrographis paniculata Burm.f. (Family:Acanthaceae) extracts against Culex quinquefasciatus (Say.) and Aedes aegypti (Linn.) (Diptera:Culicidae). Asian Pacific Journal of Tropical Medicine, 4(3), 176-81. https://doi.org/10.1016/S1995-7645(11)60064-3
Govindarajan M. Evaluation of Andrographis Paniculata Burm.f. (Family:Acanthaceae) Extracts Against Culex Quinquefasciatus (Say.) and Aedes Aegypti (Linn.) (Diptera:Culicidae). Asian Pac J Trop Med. 2011;4(3):176-81. PubMed PMID: 21771448.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of Andrographis paniculata Burm.f. (Family:Acanthaceae) extracts against Culex quinquefasciatus (Say.) and Aedes aegypti (Linn.) (Diptera:Culicidae). A1 - Govindarajan,Marimuthu, Y1 - 2011/04/12/ PY - 2010/12/02/received PY - 2010/12/27/revised PY - 2011/02/15/accepted PY - 2011/7/21/entrez PY - 2011/7/21/pubmed PY - 2012/1/24/medline SP - 176 EP - 81 JF - Asian Pacific journal of tropical medicine JO - Asian Pac J Trop Med VL - 4 IS - 3 N2 - OBJECTIVE: To investigate the larvicidal and ovicidal efficacy of different extracts of Andrographis paniculata (A. paniculata) against Culex quinquefasciatus (Cx. quinquefasciatus) Say and Aedes aegypti (Ae. aegypti) L. (Diptera: Culicidae). METHODS: Larvicidal efficacy of the crude leaf extracts of A. paniculata with five different solvents like benzene, hexane, ethyl acetate, methanol and chloroform was tested against the early third instar larvae of Cx. quinquefasciatus and Ae. aegypti. The ovicidal activity was determined against two mosquito species to various concentrations ranging from 50-300 ppm under the laboratory conditions. RESULTS: The benzene, hexane, ethyl acetate, methanol and chloroform leaf extract of A. paniculata was found to be more effective against Cx. quinquefasciatus than Ae. aegypti. The LC(50) values were 112.19, 137.48, 118.67, 102.05, 91.20 ppm and 119.58, 146.34, 124.24, 110.12, 99.54 ppm respectively. Among five tested solvent, methanol and ethyl acetate crude extract was found to be most effective for ovicidal activity against two mosquito species. The extract of methanol and ethyl acetate exerted 100% mortality at 200 ppm against Cx. quinquefasciatus and at 250 ppm against Ae. aegypti. CONCLUSIONS: From the results it can be concluded the crude extract of A. paniculata was a potential for controlling Cx. quinquefasciatus and Ae. aegypti mosquitoes. SN - 2352-4146 UR - https://www.unboundmedicine.com/medline/citation/21771448/Evaluation_of_Andrographis_paniculata_Burm_f___Family:Acanthaceae__extracts_against_Culex_quinquefasciatus__Say___and_Aedes_aegypti__Linn____Diptera:Culicidae__ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1995-7645(11)60064-3 DB - PRIME DP - Unbound Medicine ER -