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Pathologic mandibular fracture as the presenting manifestation of multiple myeloma.
J Craniofac Surg. 2011 Jul; 22(4):1312-5.JC

Abstract

The authors report on the management of a patient who presented with a pathologic mandibular fracture as the initial presenting sign of multiple myeloma. The patient underwent surgical resection of the mandibular area involved by the pathologic fracture and osteolytic lesion. Then, he was prescribed combined thalidomide, melphalan, and prednisone for systemic treatment. The patient tolerated his treatment well and is currently being followed up on outpatient basis. The treatment of a mandibular pathologic fracture associated with a solitary multiple myeloma lesion should include a segmental resection of the mandibular bone that is involved by the lesion. An appropriate reconstruction can be immediately performed or delayed. Anyway, the importance of an early beginning of systemic treatment should always be remembered.

Authors+Show Affiliations

Division of Maxillofacial Surgery, Head and Neck Department, San Giovanni Battista Hospital, University of Turin, Turin, Italy. paolo.boffano@gmail.comNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

21772196

Citation

Boffano, Paolo, et al. "Pathologic Mandibular Fracture as the Presenting Manifestation of Multiple Myeloma." The Journal of Craniofacial Surgery, vol. 22, no. 4, 2011, pp. 1312-5.
Boffano P, Viterbo S, Barreca A, et al. Pathologic mandibular fracture as the presenting manifestation of multiple myeloma. J Craniofac Surg. 2011;22(4):1312-5.
Boffano, P., Viterbo, S., Barreca, A., & Berrone, S. (2011). Pathologic mandibular fracture as the presenting manifestation of multiple myeloma. The Journal of Craniofacial Surgery, 22(4), 1312-5. https://doi.org/10.1097/SCS.0b013e31821c6cbe
Boffano P, et al. Pathologic Mandibular Fracture as the Presenting Manifestation of Multiple Myeloma. J Craniofac Surg. 2011;22(4):1312-5. PubMed PMID: 21772196.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pathologic mandibular fracture as the presenting manifestation of multiple myeloma. AU - Boffano,Paolo, AU - Viterbo,Stefano, AU - Barreca,Antonella, AU - Berrone,Sid, PY - 2011/7/21/entrez PY - 2011/7/21/pubmed PY - 2011/12/30/medline SP - 1312 EP - 5 JF - The Journal of craniofacial surgery JO - J Craniofac Surg VL - 22 IS - 4 N2 - The authors report on the management of a patient who presented with a pathologic mandibular fracture as the initial presenting sign of multiple myeloma. The patient underwent surgical resection of the mandibular area involved by the pathologic fracture and osteolytic lesion. Then, he was prescribed combined thalidomide, melphalan, and prednisone for systemic treatment. The patient tolerated his treatment well and is currently being followed up on outpatient basis. The treatment of a mandibular pathologic fracture associated with a solitary multiple myeloma lesion should include a segmental resection of the mandibular bone that is involved by the lesion. An appropriate reconstruction can be immediately performed or delayed. Anyway, the importance of an early beginning of systemic treatment should always be remembered. SN - 1536-3732 UR - https://www.unboundmedicine.com/medline/citation/21772196/Pathologic_mandibular_fracture_as_the_presenting_manifestation_of_multiple_myeloma_ L2 - http://dx.doi.org/10.1097/SCS.0b013e31821c6cbe DB - PRIME DP - Unbound Medicine ER -