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A flow-injection mass spectrometry fingerprinting method for authentication and quality assessment of Scutellaria lateriflora-based dietary supplements.
Anal Bioanal Chem. 2011 Sep; 401(5):1577-84.AB

Abstract

Scutellaria lateriflora, commonly known as skullcap, is used as an ingredient in numerous herbal products. However, it has been occasionally adulterated/contaminated with Teucrium canadense and/or Teucrium chamaedrys, commonly known as germander, due to the morphological similarities between the two genera. The latter contains hepatotoxic diterpenes. Despite the potential hepatotoxicity introduced by germander contamination, analytical methodologies for the authentication and quality assessment of S. lateriflora-based dietary supplements have not been reported. In this study, a flow-injection/mass spectrometry fingerprinting method in combination with principal component analysis was used to survey S. lateriflora-based dietary supplements sold in the USA.

Authors+Show Affiliations

Food Composition and Methods Development Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, US Department of Agriculture, Beltsville, MD 20705, USA.No affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

21773734

Citation

Sun, Jianghao, and Pei Chen. "A Flow-injection Mass Spectrometry Fingerprinting Method for Authentication and Quality Assessment of Scutellaria Lateriflora-based Dietary Supplements." Analytical and Bioanalytical Chemistry, vol. 401, no. 5, 2011, pp. 1577-84.
Sun J, Chen P. A flow-injection mass spectrometry fingerprinting method for authentication and quality assessment of Scutellaria lateriflora-based dietary supplements. Anal Bioanal Chem. 2011;401(5):1577-84.
Sun, J., & Chen, P. (2011). A flow-injection mass spectrometry fingerprinting method for authentication and quality assessment of Scutellaria lateriflora-based dietary supplements. Analytical and Bioanalytical Chemistry, 401(5), 1577-84. https://doi.org/10.1007/s00216-011-5246-2
Sun J, Chen P. A Flow-injection Mass Spectrometry Fingerprinting Method for Authentication and Quality Assessment of Scutellaria Lateriflora-based Dietary Supplements. Anal Bioanal Chem. 2011;401(5):1577-84. PubMed PMID: 21773734.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A flow-injection mass spectrometry fingerprinting method for authentication and quality assessment of Scutellaria lateriflora-based dietary supplements. AU - Sun,Jianghao, AU - Chen,Pei, Y1 - 2011/07/20/ PY - 2011/05/20/received PY - 2011/07/06/accepted PY - 2011/07/05/revised PY - 2011/7/21/entrez PY - 2011/7/21/pubmed PY - 2011/12/14/medline SP - 1577 EP - 84 JF - Analytical and bioanalytical chemistry JO - Anal Bioanal Chem VL - 401 IS - 5 N2 - Scutellaria lateriflora, commonly known as skullcap, is used as an ingredient in numerous herbal products. However, it has been occasionally adulterated/contaminated with Teucrium canadense and/or Teucrium chamaedrys, commonly known as germander, due to the morphological similarities between the two genera. The latter contains hepatotoxic diterpenes. Despite the potential hepatotoxicity introduced by germander contamination, analytical methodologies for the authentication and quality assessment of S. lateriflora-based dietary supplements have not been reported. In this study, a flow-injection/mass spectrometry fingerprinting method in combination with principal component analysis was used to survey S. lateriflora-based dietary supplements sold in the USA. SN - 1618-2650 UR - https://www.unboundmedicine.com/medline/citation/21773734/A_flow_injection_mass_spectrometry_fingerprinting_method_for_authentication_and_quality_assessment_of_Scutellaria_lateriflora_based_dietary_supplements_ L2 - https://dx.doi.org/10.1007/s00216-011-5246-2 DB - PRIME DP - Unbound Medicine ER -