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Correlation between spectral-domain optical coherence tomography findings and visual outcome after primary rhegmatogenous retinal detachment repair.
Retina. 2012 Jan; 32(1):43-53.R

Abstract

PURPOSE

To correlate the postoperative visual outcome with the spectral-domain optical coherence tomography (SD-OCT) findings in the fovea after successful rhegmatogenous retinal detachment repair. Cross-sectional, observational study.

METHODS

Thirty-five patients with preoperative macula-on rhegmatogenous retinal detachment (12 eyes) and macula-off rhegmatogenous retinal detachment (23 eyes) who underwent scleral buckling surgery for primary rhegmatogenous retinal detachment were recruited. Early Treatment Diabetic Retinopathy Study best-corrected visual acuity measurement, microperimetry, and SD-OCT examination were performed on the same day. Foveal center retinal thickness, central 1-mm subfield thickness, and outer nuclear layer thickness were measured using SD-OCT. The presence or absence of epiretinal membrane, intraretinal fluid, and subretinal fluid was assessed. The status of the external limiting membrane, inner/outer segment junction, and intermediate line was also evaluated and judged as disrupted or complete. The correlations between SD-OCT findings and either postoperative best-corrected visual acuity or retinal sensitivities for central 12° were analyzed.

RESULTS

The outer nuclear layer thickness was the only significant SD-OCT retinal measurement strongly correlated with both postoperative best-corrected visual acuity (r = 0.61; P < 0.001) and retinal sensitivities for central 12° (r = 0.53; P = 0.001). Among the SD-OCT imaging findings, status of the external limiting membrane, inner/outer segment junction, and intermediate line and the presence of intraretinal fluid showed a significantly high correlation either with best-corrected visual acuity outcome (r = -0.60; P < 0.001, r = -0.63; P < 0.001, r = -0.66; P < 0.001, and r = -0.50; P = 0.002, respectively) or with postoperative retinal sensitivities (r = -0.59; P < 0.001, r = -0.61; P < 0.001, r = -0.66; P < 0.001, r = -0.50; P = 0.002, respectively). Multivariate analysis showed that the outer nuclear layer thickness and the status of the intermediate line were the most important predictors of visual outcome (P < 0.001 and P < 0.001, respectively).

CONCLUSION

This study showed that not only the status of the external limiting membrane and the inner/outer segment junction but also the integrity of the intermediate line and the outer nuclear layer thickness changes may be important predictors of postoperative visual outcome after anatomically successful rhegmatogenous retinal detachment repair.

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Authors+Show Affiliations

Gharbiya M
Department of Ophthalmology, University of Rome La Sapienza, Rome, Italy. magda.gharbiya@tiscali.it
Grandinetti F
No affiliation info available
Scavella V
No affiliation info available
Cecere M
No affiliation info available
Esposito M
No affiliation info available
Segnalini A
No affiliation info available
Gabrieli CB
No affiliation info available

MeSH

AdultAgedAged, 80 and overCross-Sectional StudiesEpiretinal MembraneFemaleFovea CentralisHumansMaleMiddle AgedPhotoreceptor Cells, VertebratePostoperative CareRetinal DetachmentScleral BucklingTomography, Optical CoherenceVisual AcuityYoung Adult

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21778929

Citation

Gharbiya, Magda, et al. "Correlation Between Spectral-domain Optical Coherence Tomography Findings and Visual Outcome After Primary Rhegmatogenous Retinal Detachment Repair." Retina (Philadelphia, Pa.), vol. 32, no. 1, 2012, pp. 43-53.
Gharbiya M, Grandinetti F, Scavella V, et al. Correlation between spectral-domain optical coherence tomography findings and visual outcome after primary rhegmatogenous retinal detachment repair. Retina. 2012;32(1):43-53.
Gharbiya, M., Grandinetti, F., Scavella, V., Cecere, M., Esposito, M., Segnalini, A., & Gabrieli, C. B. (2012). Correlation between spectral-domain optical coherence tomography findings and visual outcome after primary rhegmatogenous retinal detachment repair. Retina (Philadelphia, Pa.), 32(1), 43-53. https://doi.org/10.1097/IAE.0b013e3182180114
Gharbiya M, et al. Correlation Between Spectral-domain Optical Coherence Tomography Findings and Visual Outcome After Primary Rhegmatogenous Retinal Detachment Repair. Retina. 2012;32(1):43-53. PubMed PMID: 21778929.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Correlation between spectral-domain optical coherence tomography findings and visual outcome after primary rhegmatogenous retinal detachment repair. AU - Gharbiya,Magda, AU - Grandinetti,Francesca, AU - Scavella,Vittorio, AU - Cecere,Michela, AU - Esposito,Mariacristina, AU - Segnalini,Alessandro, AU - Gabrieli,Corrado Balacco, PY - 2011/7/23/entrez PY - 2011/7/23/pubmed PY - 2012/3/13/medline SP - 43 EP - 53 JF - Retina (Philadelphia, Pa.) JO - Retina VL - 32 IS - 1 N2 - PURPOSE: To correlate the postoperative visual outcome with the spectral-domain optical coherence tomography (SD-OCT) findings in the fovea after successful rhegmatogenous retinal detachment repair. Cross-sectional, observational study. METHODS: Thirty-five patients with preoperative macula-on rhegmatogenous retinal detachment (12 eyes) and macula-off rhegmatogenous retinal detachment (23 eyes) who underwent scleral buckling surgery for primary rhegmatogenous retinal detachment were recruited. Early Treatment Diabetic Retinopathy Study best-corrected visual acuity measurement, microperimetry, and SD-OCT examination were performed on the same day. Foveal center retinal thickness, central 1-mm subfield thickness, and outer nuclear layer thickness were measured using SD-OCT. The presence or absence of epiretinal membrane, intraretinal fluid, and subretinal fluid was assessed. The status of the external limiting membrane, inner/outer segment junction, and intermediate line was also evaluated and judged as disrupted or complete. The correlations between SD-OCT findings and either postoperative best-corrected visual acuity or retinal sensitivities for central 12° were analyzed. RESULTS: The outer nuclear layer thickness was the only significant SD-OCT retinal measurement strongly correlated with both postoperative best-corrected visual acuity (r = 0.61; P < 0.001) and retinal sensitivities for central 12° (r = 0.53; P = 0.001). Among the SD-OCT imaging findings, status of the external limiting membrane, inner/outer segment junction, and intermediate line and the presence of intraretinal fluid showed a significantly high correlation either with best-corrected visual acuity outcome (r = -0.60; P < 0.001, r = -0.63; P < 0.001, r = -0.66; P < 0.001, and r = -0.50; P = 0.002, respectively) or with postoperative retinal sensitivities (r = -0.59; P < 0.001, r = -0.61; P < 0.001, r = -0.66; P < 0.001, r = -0.50; P = 0.002, respectively). Multivariate analysis showed that the outer nuclear layer thickness and the status of the intermediate line were the most important predictors of visual outcome (P < 0.001 and P < 0.001, respectively). CONCLUSION: This study showed that not only the status of the external limiting membrane and the inner/outer segment junction but also the integrity of the intermediate line and the outer nuclear layer thickness changes may be important predictors of postoperative visual outcome after anatomically successful rhegmatogenous retinal detachment repair. SN - 1539-2864 UR - https://www.unboundmedicine.com/medline/citation/21778929/Correlation_between_spectral_domain_optical_coherence_tomography_findings_and_visual_outcome_after_primary_rhegmatogenous_retinal_detachment_repair_ L2 - https://doi.org/10.1097/IAE.0b013e3182180114 DB - PRIME DP - Unbound Medicine ER -