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Combined effect of silica dust exposure and tobacco smoking on the prevalence of respiratory impairments among gold miners.
Scand J Work Environ Health 1990; 16(6):411-22SJ

Abstract

The combined effect of underground gold mining dust with a high content of free silica and tobacco smoking on the prevalence of respiratory impairment was examined among 2209 South African gold miners and 483 nonminers. The subjects were grouped as having normal function; minimal, moderate or marked obstruction; marked obstruction with restriction; or pure restriction on the basis of their lung function profiles. Each profile group was compared with the normal group for exposure prevalences, and additive and multiplicative relative risk models were applied to test for departure from the additivity of individual effects. Departure from additivity was found to increase progressively with the severity of obstructive impairment. The results indicated that approximately 94% of the cases with the most severe respiratory impairment (N = 191) could have been prevented through the elimination of tobacco smoking. In conclusion, tobacco smoking was found to potentiate the effect of dust on respiratory impairments.

Authors+Show Affiliations

Epidemiology Research Unit, Medical Bureau for Occupational Diseases, Johannesburg, South Africa.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

2178280

Citation

Hnizdo, E, et al. "Combined Effect of Silica Dust Exposure and Tobacco Smoking On the Prevalence of Respiratory Impairments Among Gold Miners." Scandinavian Journal of Work, Environment & Health, vol. 16, no. 6, 1990, pp. 411-22.
Hnizdo E, Baskind E, Sluis-Cremer GK. Combined effect of silica dust exposure and tobacco smoking on the prevalence of respiratory impairments among gold miners. Scand J Work Environ Health. 1990;16(6):411-22.
Hnizdo, E., Baskind, E., & Sluis-Cremer, G. K. (1990). Combined effect of silica dust exposure and tobacco smoking on the prevalence of respiratory impairments among gold miners. Scandinavian Journal of Work, Environment & Health, 16(6), pp. 411-22.
Hnizdo E, Baskind E, Sluis-Cremer GK. Combined Effect of Silica Dust Exposure and Tobacco Smoking On the Prevalence of Respiratory Impairments Among Gold Miners. Scand J Work Environ Health. 1990;16(6):411-22. PubMed PMID: 2178280.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Combined effect of silica dust exposure and tobacco smoking on the prevalence of respiratory impairments among gold miners. AU - Hnizdo,E, AU - Baskind,E, AU - Sluis-Cremer,G K, PY - 1990/12/1/pubmed PY - 1990/12/1/medline PY - 1990/12/1/entrez SP - 411 EP - 22 JF - Scandinavian journal of work, environment & health JO - Scand J Work Environ Health VL - 16 IS - 6 N2 - The combined effect of underground gold mining dust with a high content of free silica and tobacco smoking on the prevalence of respiratory impairment was examined among 2209 South African gold miners and 483 nonminers. The subjects were grouped as having normal function; minimal, moderate or marked obstruction; marked obstruction with restriction; or pure restriction on the basis of their lung function profiles. Each profile group was compared with the normal group for exposure prevalences, and additive and multiplicative relative risk models were applied to test for departure from the additivity of individual effects. Departure from additivity was found to increase progressively with the severity of obstructive impairment. The results indicated that approximately 94% of the cases with the most severe respiratory impairment (N = 191) could have been prevented through the elimination of tobacco smoking. In conclusion, tobacco smoking was found to potentiate the effect of dust on respiratory impairments. SN - 0355-3140 UR - https://www.unboundmedicine.com/medline/citation/2178280/Combined_effect_of_silica_dust_exposure_and_tobacco_smoking_on_the_prevalence_of_respiratory_impairments_among_gold_miners_ L2 - http://www.sjweh.fi/show_abstract.php?abstract_id=1768 DB - PRIME DP - Unbound Medicine ER -