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Modified percutaneous transhepatic variceal embolization with 2-octylcyanoacrylate for bleeding gastric varices: long-term follow-up outcomes.
AJR Am J Roentgenol. 2011 Aug; 197(2):502-9.AA

Abstract

OBJECTIVE

The objective of our study was to evaluate the long-term efficacy and safety of a modified percutaneous transhepatic variceal embolization procedure with 2-octylcyanoacrylate (2-OCA) in the treatment of gastric variceal bleeding.

MATERIALS AND METHODS

From January 2003 to December 2008, 71 patients with a history of gastric variceal bleeding underwent modified percutaneous transhepatic variceal embolization with 2-OCA in our hospital: 12 patients with acute gastric variceal bleeding underwent emergency obliteration and the remaining 59 patients with recent variceal bleeding underwent modified percutaneous transhepatic variceal embolization as a secondary prophylaxis. The initial hemostasis rate, rebleeding rate, survival rate, and complications were evaluated.

RESULTS

Complete obliteration--that is, all the gastric varices and their feeding veins were obliterated--was achieved after the percutaneous transhepatic variceal embolization procedure in 67 patients (94.4%). Acute variceal bleeding was arrested after the procedure in all 12 patients (100%). The mean follow-up period was 24.2 ± 12.4 (SD) months (range, 6-62 months). During the follow-up period, the cumulative probability of remaining free of gastric variceal rebleeding in patients with complete obliteration was 100%, 88.2%, and 88.2% at 1, 3, and 5 years after the procedure, respectively. Follow-up CT revealed that the modified percutaneous transhepatic variceal embolization procedure with 2-OCA can achieve long-lasting obliteration in the entire varices and in all the feeding veins. The cumulative survival rates at 1, 3, and 5 years after the procedure were 96.9%, 68.9%, and 53.7%. No severe complications occurred after the procedure.

CONCLUSION

The modified percutaneous transhepatic variceal embolization with 2-OCA is considered to be an effective and safe method for the extensive and permanent obliteration of both gastric varices and their feeding veins.

Authors+Show Affiliations

Department of Gastroenterology, Provincial Hospital Affiliated to Shandong University, 324 Jingwu Weiqi Rd, Jinan 250021, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21785101

Citation

Tian, Xiangguo, et al. "Modified Percutaneous Transhepatic Variceal Embolization With 2-octylcyanoacrylate for Bleeding Gastric Varices: Long-term Follow-up Outcomes." AJR. American Journal of Roentgenology, vol. 197, no. 2, 2011, pp. 502-9.
Tian X, Wang Q, Zhang C, et al. Modified percutaneous transhepatic variceal embolization with 2-octylcyanoacrylate for bleeding gastric varices: long-term follow-up outcomes. AJR Am J Roentgenol. 2011;197(2):502-9.
Tian, X., Wang, Q., Zhang, C., Liu, F., Cui, Y., Liu, F., & Liu, J. (2011). Modified percutaneous transhepatic variceal embolization with 2-octylcyanoacrylate for bleeding gastric varices: long-term follow-up outcomes. AJR. American Journal of Roentgenology, 197(2), 502-9. https://doi.org/10.2214/AJR.10.6005
Tian X, et al. Modified Percutaneous Transhepatic Variceal Embolization With 2-octylcyanoacrylate for Bleeding Gastric Varices: Long-term Follow-up Outcomes. AJR Am J Roentgenol. 2011;197(2):502-9. PubMed PMID: 21785101.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Modified percutaneous transhepatic variceal embolization with 2-octylcyanoacrylate for bleeding gastric varices: long-term follow-up outcomes. AU - Tian,Xiangguo, AU - Wang,Qizhi, AU - Zhang,Chunqing, AU - Liu,Fuli, AU - Cui,Yi, AU - Liu,Feng, AU - Liu,Jiyong, PY - 2011/7/26/entrez PY - 2011/7/26/pubmed PY - 2011/9/29/medline SP - 502 EP - 9 JF - AJR. American journal of roentgenology JO - AJR Am J Roentgenol VL - 197 IS - 2 N2 - OBJECTIVE: The objective of our study was to evaluate the long-term efficacy and safety of a modified percutaneous transhepatic variceal embolization procedure with 2-octylcyanoacrylate (2-OCA) in the treatment of gastric variceal bleeding. MATERIALS AND METHODS: From January 2003 to December 2008, 71 patients with a history of gastric variceal bleeding underwent modified percutaneous transhepatic variceal embolization with 2-OCA in our hospital: 12 patients with acute gastric variceal bleeding underwent emergency obliteration and the remaining 59 patients with recent variceal bleeding underwent modified percutaneous transhepatic variceal embolization as a secondary prophylaxis. The initial hemostasis rate, rebleeding rate, survival rate, and complications were evaluated. RESULTS: Complete obliteration--that is, all the gastric varices and their feeding veins were obliterated--was achieved after the percutaneous transhepatic variceal embolization procedure in 67 patients (94.4%). Acute variceal bleeding was arrested after the procedure in all 12 patients (100%). The mean follow-up period was 24.2 ± 12.4 (SD) months (range, 6-62 months). During the follow-up period, the cumulative probability of remaining free of gastric variceal rebleeding in patients with complete obliteration was 100%, 88.2%, and 88.2% at 1, 3, and 5 years after the procedure, respectively. Follow-up CT revealed that the modified percutaneous transhepatic variceal embolization procedure with 2-OCA can achieve long-lasting obliteration in the entire varices and in all the feeding veins. The cumulative survival rates at 1, 3, and 5 years after the procedure were 96.9%, 68.9%, and 53.7%. No severe complications occurred after the procedure. CONCLUSION: The modified percutaneous transhepatic variceal embolization with 2-OCA is considered to be an effective and safe method for the extensive and permanent obliteration of both gastric varices and their feeding veins. SN - 1546-3141 UR - https://www.unboundmedicine.com/medline/citation/21785101/Modified_percutaneous_transhepatic_variceal_embolization_with_2_octylcyanoacrylate_for_bleeding_gastric_varices:_long_term_follow_up_outcomes_ L2 - https://www.ajronline.org/doi/10.2214/AJR.10.6005 DB - PRIME DP - Unbound Medicine ER -