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A diagnostic challenge: acute generalized exanthematous pustulosis or pustular psoriasis due to terbinafine.
Clin Exp Dermatol. 2012 Jan; 37(1):24-7.CE

Abstract

A 72-year-old man developed a generalized erythematous pustular eruption 11 weeks after commencing terbinafine. Clinically and histologically, the appearance was that of acute generalized exanthematous pustulosis (AGEP), and the disease was managed with topical preparations. Initial improvement was marred by relapse of acute pustulosis, now more in keeping with terbinafine-induced pustular psoriasis (PP), which was successfully treated with acitretin. This case highlights the difficulty of differentiating between AGEP and PP.

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Authors+Show Affiliations

Duckworth L
Birmingham Skin Centre, City Hospital, Birmingham,UK.
Maheshwari MB
No affiliation info available
Thomson MA
No affiliation info available

MeSH

Acute Generalized Exanthematous PustulosisAgedAntifungal AgentsDiagnosis, DifferentialDrug EruptionsHumansMaleNaphthalenesPsoriasisSkin Diseases, VesiculobullousTerbinafine

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

21790726

Citation

Duckworth, L, et al. "A Diagnostic Challenge: Acute Generalized Exanthematous Pustulosis or Pustular Psoriasis Due to Terbinafine." Clinical and Experimental Dermatology, vol. 37, no. 1, 2012, pp. 24-7.
Duckworth L, Maheshwari MB, Thomson MA. A diagnostic challenge: acute generalized exanthematous pustulosis or pustular psoriasis due to terbinafine. Clin Exp Dermatol. 2012;37(1):24-7.
Duckworth, L., Maheshwari, M. B., & Thomson, M. A. (2012). A diagnostic challenge: acute generalized exanthematous pustulosis or pustular psoriasis due to terbinafine. Clinical and Experimental Dermatology, 37(1), 24-7. https://doi.org/10.1111/j.1365-2230.2011.04129.x
Duckworth L, Maheshwari MB, Thomson MA. A Diagnostic Challenge: Acute Generalized Exanthematous Pustulosis or Pustular Psoriasis Due to Terbinafine. Clin Exp Dermatol. 2012;37(1):24-7. PubMed PMID: 21790726.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A diagnostic challenge: acute generalized exanthematous pustulosis or pustular psoriasis due to terbinafine. AU - Duckworth,L, AU - Maheshwari,M B, AU - Thomson,M A, Y1 - 2011/07/25/ PY - 2011/7/28/entrez PY - 2011/7/28/pubmed PY - 2012/2/15/medline SP - 24 EP - 7 JF - Clinical and experimental dermatology JO - Clin Exp Dermatol VL - 37 IS - 1 N2 - A 72-year-old man developed a generalized erythematous pustular eruption 11 weeks after commencing terbinafine. Clinically and histologically, the appearance was that of acute generalized exanthematous pustulosis (AGEP), and the disease was managed with topical preparations. Initial improvement was marred by relapse of acute pustulosis, now more in keeping with terbinafine-induced pustular psoriasis (PP), which was successfully treated with acitretin. This case highlights the difficulty of differentiating between AGEP and PP. SN - 1365-2230 UR - https://www.unboundmedicine.com/medline/citation/21790726/A_diagnostic_challenge:_acute_generalized_exanthematous_pustulosis_or_pustular_psoriasis_due_to_terbinafine_ L2 - https://doi.org/10.1111/j.1365-2230.2011.04129.x DB - PRIME DP - Unbound Medicine ER -