Tags

Type your tag names separated by a space and hit enter

Optical coherence tomography: a new tool to assess nail disease in psoriasis?
Dermatology. 2011; 222(4):311-3.D

Abstract

BACKGROUND

Nail disease is a characteristic manifestation of the psoriatic disease spectrum but is poorly understood.

OBJECTIVE

Given the intrinsically high spatial resolution imaging capabilities of optical coherence tomography (OCT), we assessed its value in psoriatic nail disease compared to high-resolution ultrasonography (US).

METHODS

All fingernails in a psoriatic arthritis patient with nail changes were scanned with OCT, and findings were compared with high-resolution US.

RESULTS

US showed loss of trilaminar appearance in all nails, resulting in the nail plate being visualized as a single hyperechoic layer with inhomogeneous thickness. The OCT images showed much higher-resolution changes with prominent thickening in the ventral plate at the nail bed which was grossly inhomogeneous, 'eroded' and irregularly fused with the underlying epidermis, which correlated with the clinical observation of subungal hyperakeratosis.

CONCLUSION

OCT has considerable potential for the evaluation of psoriatic nail disease and may be superior to US.

Authors+Show Affiliations

NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals Trust, Leeds, UK. drsibelaydin@gmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

21791896

Citation

Aydin, Sibel Zehra, et al. "Optical Coherence Tomography: a New Tool to Assess Nail Disease in Psoriasis?" Dermatology (Basel, Switzerland), vol. 222, no. 4, 2011, pp. 311-3.
Aydin SZ, Ash Z, Del Galdo F, et al. Optical coherence tomography: a new tool to assess nail disease in psoriasis? Dermatology (Basel). 2011;222(4):311-3.
Aydin, S. Z., Ash, Z., Del Galdo, F., Marzo-Ortega, H., Wakefield, R. J., Emery, P., & McGonagle, D. (2011). Optical coherence tomography: a new tool to assess nail disease in psoriasis? Dermatology (Basel, Switzerland), 222(4), 311-3. https://doi.org/10.1159/000329434
Aydin SZ, et al. Optical Coherence Tomography: a New Tool to Assess Nail Disease in Psoriasis. Dermatology (Basel). 2011;222(4):311-3. PubMed PMID: 21791896.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Optical coherence tomography: a new tool to assess nail disease in psoriasis? AU - Aydin,Sibel Zehra, AU - Ash,Zoe, AU - Del Galdo,Francesco, AU - Marzo-Ortega,Helena, AU - Wakefield,Richard J, AU - Emery,Paul, AU - McGonagle,Dennis, Y1 - 2011/07/25/ PY - 2011/01/12/received PY - 2011/05/03/accepted PY - 2011/7/28/entrez PY - 2011/7/28/pubmed PY - 2012/1/20/medline SP - 311 EP - 3 JF - Dermatology (Basel, Switzerland) JO - Dermatology (Basel) VL - 222 IS - 4 N2 - BACKGROUND: Nail disease is a characteristic manifestation of the psoriatic disease spectrum but is poorly understood. OBJECTIVE: Given the intrinsically high spatial resolution imaging capabilities of optical coherence tomography (OCT), we assessed its value in psoriatic nail disease compared to high-resolution ultrasonography (US). METHODS: All fingernails in a psoriatic arthritis patient with nail changes were scanned with OCT, and findings were compared with high-resolution US. RESULTS: US showed loss of trilaminar appearance in all nails, resulting in the nail plate being visualized as a single hyperechoic layer with inhomogeneous thickness. The OCT images showed much higher-resolution changes with prominent thickening in the ventral plate at the nail bed which was grossly inhomogeneous, 'eroded' and irregularly fused with the underlying epidermis, which correlated with the clinical observation of subungal hyperakeratosis. CONCLUSION: OCT has considerable potential for the evaluation of psoriatic nail disease and may be superior to US. SN - 1421-9832 UR - https://www.unboundmedicine.com/medline/citation/21791896/Optical_coherence_tomography:_a_new_tool_to_assess_nail_disease_in_psoriasis L2 - https://www.karger.com?DOI=10.1159/000329434 DB - PRIME DP - Unbound Medicine ER -