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Evaluation to the antioxidant activity of total flavonoids extract from persimmon (Diospyros kaki L.) leaves.
Food Chem Toxicol. 2011 Oct; 49(10):2689-96.FC

Abstract

Persimmon leaves are commonly consumed as beverages, but are also used as a popular folk medicine in China. The purpose of this work is to assess the antioxidant activity of an extract of total flavonoids from persimmon leaves (TFPL). The effect of TFPL on total antioxidant activity, reducing power, 1,1-diphenyl-2-picrylhydrazyl (DPPH()) radical scavenging, superoxide anion (()O(2)(-)) radical scavenging, hydroxyl (OH()) radical scavenging and metal chelating activities was examined. We found that TFPL possesses considerable amounts of flavonoids (192μg catechin equivalent/g of extract). The effect of this extract in total antioxidant activity, scavenging activity of superoxide anion and hydroxyl radical, reducing power and iron chelating activity was significantly better than that of rutin. However, the effect of TFPL in free radical scavenging of DPPH() was significantly not as good as than rutin. In addition, TFPL significantly decreased the level of reactive oxygen species (ROS) and malondialdehyde (MDA), while increasing the activity of catalase (CAT), superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in MC3T3-E1 cells in a dose-dependent manner. In conclusion, TFPL possess potent antioxidant and free radical scavenging activities. These antioxidant activities could contribute, at least in part, to the traditionally claimed therapeutic benefits of persimmon leaves.

Authors+Show Affiliations

Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, PR China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

21802475

Citation

Sun, Lijun, et al. "Evaluation to the Antioxidant Activity of Total Flavonoids Extract From Persimmon (Diospyros Kaki L.) Leaves." Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association, vol. 49, no. 10, 2011, pp. 2689-96.
Sun L, Zhang J, Lu X, et al. Evaluation to the antioxidant activity of total flavonoids extract from persimmon (Diospyros kaki L.) leaves. Food Chem Toxicol. 2011;49(10):2689-96.
Sun, L., Zhang, J., Lu, X., Zhang, L., & Zhang, Y. (2011). Evaluation to the antioxidant activity of total flavonoids extract from persimmon (Diospyros kaki L.) leaves. Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association, 49(10), 2689-96. https://doi.org/10.1016/j.fct.2011.07.042
Sun L, et al. Evaluation to the Antioxidant Activity of Total Flavonoids Extract From Persimmon (Diospyros Kaki L.) Leaves. Food Chem Toxicol. 2011;49(10):2689-96. PubMed PMID: 21802475.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation to the antioxidant activity of total flavonoids extract from persimmon (Diospyros kaki L.) leaves. AU - Sun,Lijun, AU - Zhang,Jianbao, AU - Lu,Xiaoyun, AU - Zhang,Liyu, AU - Zhang,Yali, Y1 - 2011/07/23/ PY - 2011/03/18/received PY - 2011/07/13/revised PY - 2011/07/14/accepted PY - 2011/8/2/entrez PY - 2011/8/2/pubmed PY - 2012/2/23/medline SP - 2689 EP - 96 JF - Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association JO - Food Chem Toxicol VL - 49 IS - 10 N2 - Persimmon leaves are commonly consumed as beverages, but are also used as a popular folk medicine in China. The purpose of this work is to assess the antioxidant activity of an extract of total flavonoids from persimmon leaves (TFPL). The effect of TFPL on total antioxidant activity, reducing power, 1,1-diphenyl-2-picrylhydrazyl (DPPH()) radical scavenging, superoxide anion (()O(2)(-)) radical scavenging, hydroxyl (OH()) radical scavenging and metal chelating activities was examined. We found that TFPL possesses considerable amounts of flavonoids (192μg catechin equivalent/g of extract). The effect of this extract in total antioxidant activity, scavenging activity of superoxide anion and hydroxyl radical, reducing power and iron chelating activity was significantly better than that of rutin. However, the effect of TFPL in free radical scavenging of DPPH() was significantly not as good as than rutin. In addition, TFPL significantly decreased the level of reactive oxygen species (ROS) and malondialdehyde (MDA), while increasing the activity of catalase (CAT), superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in MC3T3-E1 cells in a dose-dependent manner. In conclusion, TFPL possess potent antioxidant and free radical scavenging activities. These antioxidant activities could contribute, at least in part, to the traditionally claimed therapeutic benefits of persimmon leaves. SN - 1873-6351 UR - https://www.unboundmedicine.com/medline/citation/21802475/Evaluation_to_the_antioxidant_activity_of_total_flavonoids_extract_from_persimmon__Diospyros_kaki_L___leaves_ DB - PRIME DP - Unbound Medicine ER -