Tags

Type your tag names separated by a space and hit enter

[Reduction in 28 days and 6 months of acute myocardial infarction mortality from 1995 to 2005. Data from PRIAMHO I, II and MASCARA registries].
Rev Esp Cardiol. 2011 Nov; 64(11):972-80.RE

Abstract

INTRODUCTION AND OBJECTIVES

To determine whether mortality from acute myocardial infarction has reduced in Spain and the possibly related therapeutic factors.

METHODS

Nine thousand, nine hundred and forty-nine patients with ST-segment elevation myocardial infarction admitted to the Coronary Care Unit were identified from PRIAMHO I, II and MASCARA registries performed in 1995, 2000 and 2005, with a 6 month follow-up.

RESULTS

From 1995 to 2005 patients were increasingly more likely to have hypertension, hyperlipidemia and anterior infarction, but age of onset and the proportion of females did not increase. Twenty-eight-day mortality rates were 12.6%, 12.3% and 6% in 1995, 2000 and 2005 respectively, and 15.3%, 14.6% and 9.4% at 6 months (both P-trend <.001). Multivariate analysis was performed and the adjusted odds ratio for 28-day mortality for an infarction occuring in 2005 (compared with 1995) was 0.62 (95% confidence interval: 0.44-0.88) whereas the adjusted hazard ratio for mortality at 6 months was 0.40 (95% confidence interval: 0.24-0.67). Other variables independently associated with lower mortality at 28 days were: reperfusion therapy, and the use of anti-thrombotic treatment, beta-blockers and angiotensin-converting enzyme inhibitors. The 28-day-6-month period had an independent protective effect on the following therapies: coronary reperfusion, and prescription of antiplatelet agents, beta-blockers and lipid lowering drugs upon discharge.

CONCLUSIONS

Twenty-eight-day and six-month mortality rates fell among patients with ST-elevation myocardial infarction in Spain from 1995 to 2005. The possibly related therapeutic factors were the following: more frequent reperfusion therapy and increased use of anti-thrombotic drugs, beta-blockers, angiotensin-converting enzyme inhibitors and lipid lowering drugs.

Authors+Show Affiliations

Servicio de Cardiología, Hospital Txagorritxu, José Atxotegi, s/n, 01009 Vitoria-Gasteiz, Álava, España.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

spa

PubMed ID

21803474

Citation

Arós, Fernando, et al. "[Reduction in 28 Days and 6 Months of Acute Myocardial Infarction Mortality From 1995 to 2005. Data From PRIAMHO I, II and MASCARA Registries]." Revista Espanola De Cardiologia, vol. 64, no. 11, 2011, pp. 972-80.
Arós F, Heras M, Vila J, et al. [Reduction in 28 days and 6 months of acute myocardial infarction mortality from 1995 to 2005. Data from PRIAMHO I, II and MASCARA registries]. Rev Esp Cardiol. 2011;64(11):972-80.
Arós, F., Heras, M., Vila, J., Sanz, H., Ferreira-González, I., Permanyer-Miralda, G., Cuñat, J., López-Bescós, L., Cabadés, A., Loma-Osorio, A., & Marrugat, J. (2011). [Reduction in 28 days and 6 months of acute myocardial infarction mortality from 1995 to 2005. Data from PRIAMHO I, II and MASCARA registries]. Revista Espanola De Cardiologia, 64(11), 972-80. https://doi.org/10.1016/j.recesp.2011.05.011
Arós F, et al. [Reduction in 28 Days and 6 Months of Acute Myocardial Infarction Mortality From 1995 to 2005. Data From PRIAMHO I, II and MASCARA Registries]. Rev Esp Cardiol. 2011;64(11):972-80. PubMed PMID: 21803474.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Reduction in 28 days and 6 months of acute myocardial infarction mortality from 1995 to 2005. Data from PRIAMHO I, II and MASCARA registries]. AU - Arós,Fernando, AU - Heras,Magda, AU - Vila,Joan, AU - Sanz,Héctor, AU - Ferreira-González,Ignacio, AU - Permanyer-Miralda,Gaietà, AU - Cuñat,José, AU - López-Bescós,Lorenzo, AU - Cabadés,Adolfo, AU - Loma-Osorio,Angel, AU - Marrugat,Jaume, AU - ,, Y1 - 2011/07/30/ PY - 2010/11/16/received PY - 2011/05/03/accepted PY - 2011/8/2/entrez PY - 2011/8/2/pubmed PY - 2012/3/1/medline SP - 972 EP - 80 JF - Revista espanola de cardiologia JO - Rev Esp Cardiol VL - 64 IS - 11 N2 - INTRODUCTION AND OBJECTIVES: To determine whether mortality from acute myocardial infarction has reduced in Spain and the possibly related therapeutic factors. METHODS: Nine thousand, nine hundred and forty-nine patients with ST-segment elevation myocardial infarction admitted to the Coronary Care Unit were identified from PRIAMHO I, II and MASCARA registries performed in 1995, 2000 and 2005, with a 6 month follow-up. RESULTS: From 1995 to 2005 patients were increasingly more likely to have hypertension, hyperlipidemia and anterior infarction, but age of onset and the proportion of females did not increase. Twenty-eight-day mortality rates were 12.6%, 12.3% and 6% in 1995, 2000 and 2005 respectively, and 15.3%, 14.6% and 9.4% at 6 months (both P-trend <.001). Multivariate analysis was performed and the adjusted odds ratio for 28-day mortality for an infarction occuring in 2005 (compared with 1995) was 0.62 (95% confidence interval: 0.44-0.88) whereas the adjusted hazard ratio for mortality at 6 months was 0.40 (95% confidence interval: 0.24-0.67). Other variables independently associated with lower mortality at 28 days were: reperfusion therapy, and the use of anti-thrombotic treatment, beta-blockers and angiotensin-converting enzyme inhibitors. The 28-day-6-month period had an independent protective effect on the following therapies: coronary reperfusion, and prescription of antiplatelet agents, beta-blockers and lipid lowering drugs upon discharge. CONCLUSIONS: Twenty-eight-day and six-month mortality rates fell among patients with ST-elevation myocardial infarction in Spain from 1995 to 2005. The possibly related therapeutic factors were the following: more frequent reperfusion therapy and increased use of anti-thrombotic drugs, beta-blockers, angiotensin-converting enzyme inhibitors and lipid lowering drugs. SN - 1579-2242 UR - https://www.unboundmedicine.com/medline/citation/21803474/[Reduction_in_28_days_and_6_months_of_acute_myocardial_infarction_mortality_from_1995_to_2005__Data_from_PRIAMHO_I_II_and_MASCARA_registries]_ L2 - http://www.revespcardiol.org/en/linksolver/ft/pii/S0300-8932(11)00523-9 DB - PRIME DP - Unbound Medicine ER -