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Antimicrobial properties, antioxidant activity and bioactive compounds from six wild edible mushrooms of western ghats of Karnataka, India.
Pharmacognosy Res. 2010 Mar; 2(2):107-12.PR

Abstract

Methanolic extracts of 6 wild edible mushrooms isolated from the Western Ghats of Karnataka were used in this study. Among the isolates (Lycoperdon perlatum, Cantharellus cibarius, Clavaria vermiculris, Ramaria formosa, Marasmius oreades, Pleurotus pulmonarius), only 4 showed satisfactory results. Quantitative analysis of bioactive components revealed that total phenols are the major bioactive component found in extracts of isolates expressed as mg of GAE per gram of fruit body, which ranged from 3.20 ± 0.05 mg/mL to 6.25 ± 0.08 mg/mL. Average concentration of flavonoid ranged from 0.40 ± 0.052 mg/mL to 2.54 ± 0.08 mg/mL; followed by very small concentration of ascorbic acid (range, 0.06 ± 0.01 mg/mL to 0.16 ± 0.01 mg/mL) in all the isolates. All the isolates showed high phenol and flavonoid content, but ascorbic acid content was found in traces. Antioxidant efficiency by inhibitory concentration on 1,1-Diphenly-2-picrylhydrazyl (DPPH) was found significant when compared to standard antioxidant like Buthylated hydroxyanisol (BHA). The concentration (IC(50)) ranged from 0.94 ± 0.27 mg/mL to 7.57 ± 0.21 mg/mL. Determination of antimicrobial activity profile of all the isolates tested against a panel of standard pathogenic bacteria and fungi indicated that the concentrations of bioactive components directly influence the antimicrobial capability of the isolates. Agar diffusion assay showed considerable activity against all bacteria. Minimum inhibitory concentration values of the extracts of 4 isolates showed that they are also active even in least concentrations. These results are discussed in relation to therapeutic value of the studied mushrooms.

Authors+Show Affiliations

Mycology Laboratory, Department of Botany, Karnatak University, Dharwad 580 003, Karnataka, India.No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

21808550

Citation

Ramesh, Ch, and Manohar G. Pattar. "Antimicrobial Properties, Antioxidant Activity and Bioactive Compounds From Six Wild Edible Mushrooms of Western Ghats of Karnataka, India." Pharmacognosy Research, vol. 2, no. 2, 2010, pp. 107-12.
Ramesh Ch, Pattar MG. Antimicrobial properties, antioxidant activity and bioactive compounds from six wild edible mushrooms of western ghats of Karnataka, India. Pharmacognosy Res. 2010;2(2):107-12.
Ramesh, C. h., & Pattar, M. G. (2010). Antimicrobial properties, antioxidant activity and bioactive compounds from six wild edible mushrooms of western ghats of Karnataka, India. Pharmacognosy Research, 2(2), 107-12. https://doi.org/10.4103/0974-8490.62953
Ramesh Ch, Pattar MG. Antimicrobial Properties, Antioxidant Activity and Bioactive Compounds From Six Wild Edible Mushrooms of Western Ghats of Karnataka, India. Pharmacognosy Res. 2010;2(2):107-12. PubMed PMID: 21808550.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antimicrobial properties, antioxidant activity and bioactive compounds from six wild edible mushrooms of western ghats of Karnataka, India. AU - Ramesh,Ch, AU - Pattar,Manohar G, PY - 2009/12/24/received PY - 2009/12/27/revised PY - 2010/05/04/accepted PY - 2011/8/3/entrez PY - 2010/3/1/pubmed PY - 2010/3/1/medline KW - Agar diffusion assay KW - DPPH mushrooms KW - Western Ghats KW - antioxidant KW - bioactive KW - in-vitro SP - 107 EP - 12 JF - Pharmacognosy research JO - Pharmacognosy Res VL - 2 IS - 2 N2 - Methanolic extracts of 6 wild edible mushrooms isolated from the Western Ghats of Karnataka were used in this study. Among the isolates (Lycoperdon perlatum, Cantharellus cibarius, Clavaria vermiculris, Ramaria formosa, Marasmius oreades, Pleurotus pulmonarius), only 4 showed satisfactory results. Quantitative analysis of bioactive components revealed that total phenols are the major bioactive component found in extracts of isolates expressed as mg of GAE per gram of fruit body, which ranged from 3.20 ± 0.05 mg/mL to 6.25 ± 0.08 mg/mL. Average concentration of flavonoid ranged from 0.40 ± 0.052 mg/mL to 2.54 ± 0.08 mg/mL; followed by very small concentration of ascorbic acid (range, 0.06 ± 0.01 mg/mL to 0.16 ± 0.01 mg/mL) in all the isolates. All the isolates showed high phenol and flavonoid content, but ascorbic acid content was found in traces. Antioxidant efficiency by inhibitory concentration on 1,1-Diphenly-2-picrylhydrazyl (DPPH) was found significant when compared to standard antioxidant like Buthylated hydroxyanisol (BHA). The concentration (IC(50)) ranged from 0.94 ± 0.27 mg/mL to 7.57 ± 0.21 mg/mL. Determination of antimicrobial activity profile of all the isolates tested against a panel of standard pathogenic bacteria and fungi indicated that the concentrations of bioactive components directly influence the antimicrobial capability of the isolates. Agar diffusion assay showed considerable activity against all bacteria. Minimum inhibitory concentration values of the extracts of 4 isolates showed that they are also active even in least concentrations. These results are discussed in relation to therapeutic value of the studied mushrooms. SN - 0974-8490 UR - https://www.unboundmedicine.com/medline/citation/21808550/Antimicrobial_properties_antioxidant_activity_and_bioactive_compounds_from_six_wild_edible_mushrooms_of_western_ghats_of_Karnataka_India_ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21808550/ DB - PRIME DP - Unbound Medicine ER -
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